(data stored in ACNUC7421 zone)

SWISSPROT: YCBK_BACSU

ID   YCBK_BACSU              Reviewed;         312 AA.
AC   P42243;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   11-DEC-2019, entry version 112.
DE   RecName: Full=Uncharacterized transporter YcbK;
GN   Name=ycbK; OrderedLocusNames=BSU02540;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=7704254; DOI=10.1099/13500872-141-2-269;
RA   Ogawa K., Akagawa E., Nakamura K., Yamane K.;
RT   "Determination of a 21548 bp nucleotide sequence around the 24 degrees
RT   region of the Bacillus subtilis chromosome.";
RL   Microbiology 141:269-275(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the EamA transporter family. {ECO:0000305}.
DR   EMBL; D30808; BAA06475.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12048.1; -; Genomic_DNA.
DR   PIR; E69753; E69753.
DR   RefSeq; NP_388136.1; NC_000964.3.
DR   RefSeq; WP_003246325.1; NZ_JNCM01000030.1.
DR   STRING; 224308.BSU02540; -.
DR   TCDB; 2.A.7.3.74; the drug/metabolite transporter (dmt) superfamily.
DR   PaxDb; P42243; -.
DR   PRIDE; P42243; -.
DR   EnsemblBacteria; CAB12048; CAB12048; BSU02540.
DR   GeneID; 938405; -.
DR   KEGG; bsu:BSU02540; -.
DR   PATRIC; fig|224308.179.peg.262; -.
DR   eggNOG; ENOG4106UX7; Bacteria.
DR   eggNOG; ENOG410XSC7; LUCA.
DR   HOGENOM; HOG000140812; -.
DR   InParanoid; P42243; -.
DR   OMA; YRMLFAL; -.
DR   PhylomeDB; P42243; -.
DR   BioCyc; BSUB:BSU02540-MONOMER; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000620; EamA_dom.
DR   Pfam; PF00892; EamA; 2.
PE   3: Inferred from homology;
DR   PRODOM; P42243.
DR   SWISS-2DPAGE; P42243.
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..312
FT                   /note="Uncharacterized transporter YcbK"
FT                   /id="PRO_0000108178"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        105..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        198..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        229..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        260..280
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        283..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          173..303
FT                   /note="EamA"
SQ   SEQUENCE   312 AA;  33969 MW;  33CDD6F0BCFAFCEC CRC64;
     MRAEEQSKIR EAAAGTIFLL IGTVCFASKS IWIKWAYQMG AEPDAVLLYR QLLAVPLFWL
     IFLIYRPPMP DGKKKGDLWK ACGAGVFCFF LSPLLDFIGL NHVSAMVERI LLMSYPLFVF
     GFTACRDRKM SSIQDLFAVL AVMFGLFLAL GGWNAELFQA NMIGAVFILL SSAVYAGYLV
     LSGHLVHQIG GIRLNAYGMT AAGAAMMLYT GIKSAAGMNT PMAAYPLSMY GLFAVIAVVT
     TVIPFVLMLE GIKRIGAQRA AAISMAGPIL TIFYGALFLG ERLGLIQVIG CGGVFFVITG
     MEYRKLKTGK KE
//

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