(data stored in ACNUC7421 zone)

SWISSPROT: YCBU_BACSU

ID   YCBU_BACSU              Reviewed;         370 AA.
AC   P42253; O34388;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 3.
DT   11-DEC-2019, entry version 119.
DE   RecName: Full=Uncharacterized aminotransferase YcbU;
DE            EC=2.6.1.-;
GN   Name=ycbU; OrderedLocusNames=BSU02660;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9274031; DOI=10.1099/00221287-143-8-2775;
RA   Kumano M., Tamakoshi A., Yamane K.;
RT   "A 32 kb nucleotide sequence from the region of the lincomycin-resistance
RT   gene (22 degrees-25 degrees) of the Bacillus subtilis chromosome and
RT   identification of the site of the lin-2 mutation.";
RL   Microbiology 143:2775-2782(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   SEQUENCE REVISION TO 92.
RX   PubMed=19383706; DOI=10.1099/mic.0.027839-0;
RA   Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A.,
RA   Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.;
RT   "From a consortium sequence to a unified sequence: the Bacillus subtilis
RT   168 reference genome a decade later.";
RL   Microbiology 155:1758-1775(2009).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-319.
RC   STRAIN=168;
RX   PubMed=7704254; DOI=10.1099/13500872-141-2-269;
RA   Ogawa K., Akagawa E., Nakamura K., Yamane K.;
RT   "Determination of a 21548 bp nucleotide sequence around the 24 degrees
RT   region of the Bacillus subtilis chromosome.";
RL   Microbiology 141:269-275(1995).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-147.
RC   STRAIN=168;
RX   PubMed=1353026; DOI=10.1016/0014-5793(92)80656-2;
RA   Awade A., Cleuziat P., Gonzales T., Robert-Baudouy J.;
RT   "Characterization of the pcp gene encoding the pyrrolidone carboxyl
RT   peptidase of Bacillus subtilis.";
RL   FEBS Lett. 305:67-73(1992).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the class-V pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=X66034; Type=Frameshift; Evidence={ECO:0000305};
DR   EMBL; AB000617; BAA22227.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12060.2; -; Genomic_DNA.
DR   EMBL; D30808; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; X66034; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; E69754; E69754.
DR   RefSeq; NP_388148.2; NC_000964.3.
DR   RefSeq; WP_003246392.1; NZ_JNCM01000030.1.
DR   SMR; P42253; -.
DR   STRING; 224308.BSU02660; -.
DR   PaxDb; P42253; -.
DR   PRIDE; P42253; -.
DR   EnsemblBacteria; CAB12060; CAB12060; BSU02660.
DR   GeneID; 938393; -.
DR   KEGG; bsu:BSU02660; -.
DR   PATRIC; fig|224308.179.peg.276; -.
DR   eggNOG; ENOG4107EPV; Bacteria.
DR   eggNOG; COG0520; LUCA.
DR   HOGENOM; HOG000017511; -.
DR   InParanoid; P42253; -.
DR   OMA; RVSPHIY; -.
DR   PhylomeDB; P42253; -.
DR   BioCyc; BSUB:BSU02660-MONOMER; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.640.10; -; 1.
DR   Gene3D; 3.90.1150.10; -; 1.
DR   InterPro; IPR000192; Aminotrans_V_dom.
DR   InterPro; IPR020578; Aminotrans_V_PyrdxlP_BS.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_dom1.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   Pfam; PF00266; Aminotran_5; 1.
DR   SUPFAM; SSF53383; SSF53383; 1.
DR   PROSITE; PS00595; AA_TRANSFER_CLASS_5; 1.
PE   3: Inferred from homology;
DR   PRODOM; P42253.
DR   SWISS-2DPAGE; P42253.
KW   Aminotransferase; Pyridoxal phosphate; Reference proteome; Transferase.
FT   CHAIN           1..370
FT                   /note="Uncharacterized aminotransferase YcbU"
FT                   /id="PRO_0000001305"
FT   MOD_RES         207
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000250"
FT   CONFLICT        92
FT                   /note="S -> Y (in Ref. 1; BAA22227 and 4; D30808)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        133
FT                   /note="L -> V (in Ref. 5; X66034)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        319
FT                   /note="D -> I (in Ref. 4; D30808)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   370 AA;  40734 MW;  E04B1E5EB6C7DC30 CRC64;
     MEHLPEQYRQ LFPTLQTHTM LASCSQSALA EPVSRAIQDY YDSLLYKGTN WKEAIEKTEF
     ARNEFAKLIG AEPDEVAIVP SVSDALVSVA SSLTAFGKKH VVYTDMDFPA VPHVWQAHSD
     YTVSVIPSID GVLPLEQYET HISDETVLTC VPHVHYRDGY VQDIKAIAEI SQRKGSLLFV
     DAYQSAGHIP IDVKEWGVDM LAAGTRKYLL GIPGVAFLYV RKELADALKP KASAWFGRES
     GFDGAYAKVA RRFQTGTPAF ISVYAAAAAL SLLNHIGVSH IRDHVKTICA DAVQYAAEKG
     LQLAAAQGGI QPGMVAIRDE RASETAGLLK KKKVICAPRE NVIRLAPHFY NTKEEMRHAI
     DEIAAKTIHK
//

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