(data stored in ACNUC7421 zone)

SWISSPROT: GERKB_BACSU

ID   GERKB_BACSU             Reviewed;         373 AA.
AC   P49940;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   11-DEC-2019, entry version 106.
DE   RecName: Full=Spore germination protein KB;
GN   Name=gerKB; OrderedLocusNames=BSU03720;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RA   Irie R., Fujita Y.Y.F., Kobayasi M.;
RT   "Nucleotide sequence and gene organization of the gerK spore germinating
RT   locus of Bacillus subtilis 168.";
RL   Submitted (NOV-1995) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=8969502; DOI=10.1099/13500872-142-11-3047;
RA   Yamane K., Kumano M., Kurita K.;
RT   "The 25 degrees-36 degrees region of the Bacillus subtilis chromosome:
RT   determination of the sequence of a 146 kb segment and identification of 113
RT   genes.";
RL   Microbiology 142:3047-3056(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- FUNCTION: Involved in the germination response to the combination of
CC       glucose, fructose, L-asparagine, and KCl.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC       superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.
CC       {ECO:0000305}.
DR   EMBL; D78187; BAA11256.1; -; Genomic_DNA.
DR   EMBL; D50453; BAA09004.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12180.1; -; Genomic_DNA.
DR   PIR; I39860; I39860.
DR   RefSeq; NP_388254.1; NC_000964.3.
DR   RefSeq; WP_003234509.1; NZ_JNCM01000031.1.
DR   STRING; 224308.BSU03720; -.
DR   TCDB; 2.A.3.9.3; the amino acid-polyamine-organocation (apc) family.
DR   PaxDb; P49940; -.
DR   PRIDE; P49940; -.
DR   EnsemblBacteria; CAB12180; CAB12180; BSU03720.
DR   GeneID; 938282; -.
DR   KEGG; bsu:BSU03720; -.
DR   PATRIC; fig|224308.179.peg.392; -.
DR   HOGENOM; HOG000246428; -.
DR   InParanoid; P49940; -.
DR   KO; K06296; -.
DR   OMA; YILYFAY; -.
DR   PhylomeDB; P49940; -.
DR   BioCyc; BSUB:BSU03720-MONOMER; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009847; P:spore germination; IEA:InterPro.
DR   InterPro; IPR004761; Spore_GerAB.
DR   PANTHER; PTHR34975; PTHR34975; 1.
DR   Pfam; PF03845; Spore_permease; 1.
DR   TIGRFAMs; TIGR00912; 2A0309; 1.
PE   3: Inferred from homology;
DR   PRODOM; P49940.
DR   SWISS-2DPAGE; P49940.
KW   Cell membrane; Germination; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..373
FT                   /note="Spore germination protein KB"
FT                   /id="PRO_0000087464"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        105..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        219..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        269..289
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        306..326
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        338..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   373 AA;  41770 MW;  6B97E3A520DC98BF CRC64;
     MEKARISIRQ LFVMIIIFEL GSSLLITPGS MAGRDAWIAV LLGCAIGLFL FYLYQGIYQC
     YPNSSPKEYM DDMLGTKLSW LFSFLYILYF AYIAARVLRD FGEMLLTFAY HDTPIIIVNA
     LLMVVSIYAV RKGIEVLARA AELLFGAMYL LGAIGLVLII VSGTIDPHNL KPVLANGISP
     VLHSVFTQTM YVPFGEVVLF VMIFPNLNDR KDVKKMGMIA MAISGLIVAL TVAINISVLD
     VDLTLRSQFP LLSTIQTIKV EEFLDRLDVF FMLALIIGGF FKVSLYLYAT VVGTSTLFKE
     KNPSQLAYPM GLGILILSIT IATNFSEHLN EGLNVVPLYI HLPFQLLFPL FLFIVAVWKK
     KRREKSKGEE AKK
//

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