(data stored in SCRATCH zone)

SWISSPROT: GLCU_BACSU

ID   GLCU_BACSU              Reviewed;         287 AA.
AC   P40420; P94429;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 2.
DT   11-DEC-2019, entry version 119.
DE   RecName: Full=Glucose uptake protein GlcU;
GN   Name=glcU; Synonyms=ycxE; OrderedLocusNames=BSU03920;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=8969502; DOI=10.1099/13500872-142-11-3047;
RA   Yamane K., Kumano M., Kurita K.;
RT   "The 25 degrees-36 degrees region of the Bacillus subtilis chromosome:
RT   determination of the sequence of a 146 kb segment and identification of 113
RT   genes.";
RL   Microbiology 142:3047-3056(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-9.
RX   PubMed=3141376; DOI=10.1128/jb.170.11.5086-5092.1988;
RA   Rather P.N., Moran C.P. Jr.;
RT   "Compartment-specific transcription in Bacillus subtilis: identification of
RT   the promoter for gdh.";
RL   J. Bacteriol. 170:5086-5092(1988).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 272-287.
RX   PubMed=3082854; DOI=10.1128/jb.166.1.238-243.1986;
RA   Lampel K.A., Uratani B., Chaudhry G.R., Ramaley R.F., Rudikoff S.;
RT   "Characterization of the developmentally regulated Bacillus subtilis
RT   glucose dehydrogenase gene.";
RL   J. Bacteriol. 166:238-243(1986).
RN   [5]
RP   FUNCTION.
RX   PubMed=10438764;
RA   Fiegler H., Bassias J., Jankovic I., Brueckner R.;
RT   "Identification of a gene in Staphylococcus xylosus encoding a novel
RT   glucose uptake protein.";
RL   J. Bacteriol. 181:4929-4936(1999).
CC   -!- FUNCTION: Involved in the uptake of glucose.
CC       {ECO:0000269|PubMed:10438764}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: Expressed during sporulation.
CC   -!- SIMILARITY: Belongs to the GRP transporter (TC 2.A.7.5) family.
CC       {ECO:0000305}.
DR   EMBL; D50453; BAA09023.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12200.1; -; Genomic_DNA.
DR   EMBL; M23547; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; M12276; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; G69766; G69766.
DR   RefSeq; NP_388274.1; NC_000964.3.
DR   RefSeq; WP_003234455.1; NZ_JNCM01000031.1.
DR   STRING; 224308.BSU03920; -.
DR   TCDB; 2.A.7.5.4; the drug/metabolite transporter (dmt) superfamily.
DR   PaxDb; P40420; -.
DR   PRIDE; P40420; -.
DR   EnsemblBacteria; CAB12200; CAB12200; BSU03920.
DR   GeneID; 938268; -.
DR   KEGG; bsu:BSU03920; -.
DR   PATRIC; fig|224308.179.peg.415; -.
DR   eggNOG; COG4975; LUCA.
DR   HOGENOM; HOG000198172; -.
DR   InParanoid; P40420; -.
DR   KO; K05340; -.
DR   OMA; VNTKMGG; -.
DR   PhylomeDB; P40420; -.
DR   BioCyc; BSUB:BSU03920-MONOMER; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   InterPro; IPR010651; Sugar_transport.
DR   PANTHER; PTHR16119; PTHR16119; 1.
DR   Pfam; PF06800; Sugar_transport; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; P40420.
DR   SWISS-2DPAGE; P40420.
KW   Cell membrane; Membrane; Reference proteome; Sporulation; Sugar transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..287
FT                   /note="Glucose uptake protein GlcU"
FT                   /id="PRO_0000213623"
FT   TRANSMEM        4..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        38..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        110..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        153..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        180..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        210..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        232..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        261..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   287 AA;  30892 MW;  E0FF3B0B47EBC56A CRC64;
     MDLLLALLPA LFWGSIVLFN VKLGGGPYSQ TLGTTIGALI VSIVIYFFVQ PVLSLRIFIV
     GIVSGLFWSL GQANQLKSIQ LMGVSKTMPI STGMQLVSTS LFGVIVFREW STPIAITLGV
     LALIFIIVGI ILTSLEDKND KKEGEPSNLK KGILILLVST LGYLVYVVVA RLFNVSGWSA
     LLPQAIGMVV GGLVLTYRHK PFNKYAIRNI LPGLIWAGGN MFLFISQPRV GVATSFSLSQ
     MGIVISTLGG IFILREKKTK RQLIAIAIGI ILIIAAAVFL GIAKTNS
//

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