(data stored in SCRATCH zone)

SWISSPROT: GS39_BACSU

ID   GS39_BACSU              Reviewed;         286 AA.
AC   P80873; P96577;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   11-DEC-2019, entry version 115.
DE   RecName: Full=General stress protein 39;
DE            Short=GSP39;
DE            EC=1.-.-.-;
GN   Name=ydaD; OrderedLocusNames=BSU04190;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RA   Kasahara Y., Nakai S., Lee S., Sadaie Y., Ogasawara N.;
RT   "A 148 kbp sequence of the region between 35 and 47 degree of the Bacillus
RT   subtilis genome.";
RL   Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   PROTEIN SEQUENCE OF 2-30.
RC   STRAIN=168 / IS58;
RX   PubMed=9298659; DOI=10.1002/elps.1150180820;
RA   Antelmann H., Bernhardt J., Schmid R., Mach H., Voelker U., Hecker M.;
RT   "First steps from a two-dimensional protein index towards a response-
RT   regulation map for Bacillus subtilis.";
RL   Electrophoresis 18:1451-1463(1997).
CC   -!- INDUCTION: By heat shock, salt stress, oxidative stress, glucose
CC       limitation and oxygen limitation.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
DR   EMBL; AB001488; BAA19257.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12226.1; -; Genomic_DNA.
DR   PIR; D69768; D69768.
DR   RefSeq; NP_388300.1; NC_000964.3.
DR   RefSeq; WP_003246648.1; NZ_JNCM01000031.1.
DR   SMR; P80873; -.
DR   STRING; 224308.BSU04190; -.
DR   PaxDb; P80873; -.
DR   PRIDE; P80873; -.
DR   EnsemblBacteria; CAB12226; CAB12226; BSU04190.
DR   GeneID; 938251; -.
DR   KEGG; bsu:BSU04190; -.
DR   PATRIC; fig|224308.179.peg.445; -.
DR   eggNOG; ENOG4105CYX; Bacteria.
DR   eggNOG; ENOG410XNUN; LUCA.
DR   InParanoid; P80873; -.
DR   OMA; NIYAPFW; -.
DR   PhylomeDB; P80873; -.
DR   BioCyc; BSUB:BSU04190-MONOMER; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR002347; SDR_fam.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   1: Evidence at protein level;
DR   PRODOM; P80873.
DR   SWISS-2DPAGE; P80873.
KW   Direct protein sequencing; Oxidoreductase; Reference proteome;
KW   Stress response.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:9298659"
FT   CHAIN           2..286
FT                   /note="General stress protein 39"
FT                   /id="PRO_0000054842"
FT   NP_BIND         46..70
FT                   /note="NAD or NADP"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        191
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10001"
FT   BINDING         178
FT                   /note="Substrate"
FT                   /evidence="ECO:0000250"
FT   CONFLICT        22
FT                   /note="E -> G (in Ref. 3; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        27
FT                   /note="P -> K (in Ref. 3; AA sequence)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   286 AA;  31082 MW;  79ADB93C323F810F CRC64;
     MANYPKELPA QTQSRQPGIE SEMNPSPVYE YEDYKGADKL KGKVALITGG DSGIGRAVSV
     AYAKEGADIA IVYKDEHEDA EETKKRVEQE GVKCLLIAGD VGEEEFCNEA VEKTVKELGG
     LDILVNNAGE QHPKESIKDI TSEQLHRTFK TNFYSQFYLT KKAIDYLKPG SAIINTTSIN
     PYVGNPTLID YTATKGAINA FTRTMAQALV KDGIRVNAVA PGPIWTPLIP ATFPEETVAQ
     FGQDTPMGRP GQPVEHVGCY VLLASDESSY MTGQTLHVNG GNFVTT
//

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