(data stored in ACNUC7421 zone)

SWISSPROT: DLYKI_BACSU

ID   DLYKI_BACSU             Reviewed;         167 AA.
AC   P96578;
DT   11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   11-DEC-2019, entry version 95.
DE   RecName: Full=Probable D-lyxose ketol-isomerase;
DE            EC=5.3.1.15;
GN   Name=ydaE; OrderedLocusNames=BSU04200;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RA   Kasahara Y., Nakai S., Lee S., Sadaie Y., Ogasawara N.;
RT   "A 148 kbp sequence of the region between 35 and 47 degree of the Bacillus
RT   subtilis genome.";
RL   Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-lyxose = D-xylulose; Xref=Rhea:RHEA:14201,
CC         ChEBI:CHEBI:16789, ChEBI:CHEBI:17140; EC=5.3.1.15;
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the D-lyxose ketol-isomerase family.
CC       {ECO:0000305}.
DR   EMBL; AB001488; BAA19258.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12227.1; -; Genomic_DNA.
DR   PIR; E69768; E69768.
DR   RefSeq; NP_388301.1; NC_000964.3.
DR   RefSeq; WP_003234400.1; NZ_JNCM01000031.1.
DR   PDB; 2Y0O; X-ray; 1.23 A; A=1-167.
DR   PDBsum; 2Y0O; -.
DR   SMR; P96578; -.
DR   STRING; 224308.BSU04200; -.
DR   PaxDb; P96578; -.
DR   PRIDE; P96578; -.
DR   EnsemblBacteria; CAB12227; CAB12227; BSU04200.
DR   GeneID; 938182; -.
DR   KEGG; bsu:BSU04200; -.
DR   PATRIC; fig|224308.179.peg.446; -.
DR   eggNOG; COG3822; LUCA.
DR   HOGENOM; HOG000008745; -.
DR   InParanoid; P96578; -.
DR   KO; K09988; -.
DR   OMA; TFRCRWG; -.
DR   BioCyc; BSUB:BSU04200-MONOMER; -.
DR   BRENDA; 5.3.1.15; 658.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0047828; F:D-lyxose ketol-isomerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR011051; RmlC_Cupin_sf.
DR   SUPFAM; SSF51182; SSF51182; 1.
PE   1: Evidence at protein level;
DR   PRODOM; P96578.
DR   SWISS-2DPAGE; P96578.
KW   3D-structure; Carbohydrate metabolism; Isomerase; Manganese; Metal-binding;
KW   Reference proteome.
FT   CHAIN           1..167
FT                   /note="Probable D-lyxose ketol-isomerase"
FT                   /id="PRO_0000049486"
FT   HELIX           5..14
FT                   /evidence="ECO:0000244|PDB:2Y0O"
FT   HELIX           21..24
FT                   /evidence="ECO:0000244|PDB:2Y0O"
FT   STRAND          28..30
FT                   /evidence="ECO:0000244|PDB:2Y0O"
FT   TURN            37..39
FT                   /evidence="ECO:0000244|PDB:2Y0O"
FT   STRAND          42..49
FT                   /evidence="ECO:0000244|PDB:2Y0O"
FT   STRAND          51..60
FT                   /evidence="ECO:0000244|PDB:2Y0O"
FT   STRAND          65..70
FT                   /evidence="ECO:0000244|PDB:2Y0O"
FT   STRAND          82..98
FT                   /evidence="ECO:0000244|PDB:2Y0O"
FT   HELIX           109..114
FT                   /evidence="ECO:0000244|PDB:2Y0O"
FT   STRAND          119..123
FT                   /evidence="ECO:0000244|PDB:2Y0O"
FT   STRAND          128..131
FT                   /evidence="ECO:0000244|PDB:2Y0O"
FT   STRAND          137..153
FT                   /evidence="ECO:0000244|PDB:2Y0O"
FT   HELIX           157..159
FT                   /evidence="ECO:0000244|PDB:2Y0O"
FT   STRAND          161..164
FT                   /evidence="ECO:0000244|PDB:2Y0O"
SQ   SEQUENCE   167 AA;  19252 MW;  16154473125D5CBD CRC64;
     MGITKEEVNS YYQKAGIVLT DEEVDQIQLM DYGLGKERKV GLQLFVYVNT DRYCSKELVL
     FPGQTCPEHR HPPVDGQEGK QETFRCRYGK VYLYVEGEKT PLPKVLPPQE DREHYTVWHE
     IELEPGGQYT IPPNTKHWFQ AGEEGAVVTE MSSTSTDKHD IFTDPRI
//

If you have problems or comments...

PBIL Back to PBIL home page