(data stored in ACNUC1104 zone)

SWISSPROT: Q9FBP4_STRCO

ID   Q9FBP4_STRCO            Unreviewed;       312 AA.
AC   Q9FBP4;
DT   01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2001, sequence version 1.
DT   11-DEC-2019, entry version 111.
DE   SubName: Full=Hydrogen peroxide sensing regulator {ECO:0000313|EMBL:CAC05878.1};
DE   SubName: Full=LysR family hydrogen peroxide-inducible transcriptional activator {ECO:0000313|EMBL:TYP12683.1};
GN   OrderedLocusNames=SCO5033 {ECO:0000313|EMBL:CAC05878.1};
GN   ORFNames=FHV98_108269 {ECO:0000313|EMBL:TYP12683.1};
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226 {ECO:0000313|Proteomes:UP000001973};
RN   [1] {ECO:0000313|EMBL:CAC05878.1, ECO:0000313|Proteomes:UP000001973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A3 {ECO:0000313|EMBL:CAC05878.1}, and ATCC BAA-471 / A3(2) /
RC   M145 {ECO:0000313|Proteomes:UP000001973};
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA   Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
RN   [2] {ECO:0000313|EMBL:TYP12683.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ICSSB 1010 {ECO:0000313|EMBL:TYP12683.1};
RA   Yuzawa S.;
RT   "Genome sequencing of Streptomyces strains engineered using actinophage
RT   integration system.";
RL   Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|SAAS:SAAS01096700}.
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DR   EMBL; AL939122; CAC05878.1; -; Genomic_DNA.
DR   EMBL; VNID01000008; TYP12683.1; -; Genomic_DNA.
DR   RefSeq; NP_629185.1; NC_003888.3.
DR   RefSeq; WP_003973944.1; NC_003888.3.
DR   STRING; 100226.SCO5033; -.
DR   EnsemblBacteria; CAC05878; CAC05878; CAC05878.
DR   GeneID; 1100474; -.
DR   KEGG; sco:SCO5033; -.
DR   PATRIC; fig|100226.15.peg.5111; -.
DR   eggNOG; ENOG4105C5Q; Bacteria.
DR   eggNOG; ENOG410XNR2; LUCA.
DR   HOGENOM; HOG000233514; -.
DR   InParanoid; Q9FBP4; -.
DR   KO; K04761; -.
DR   OMA; YLMPRMI; -.
DR   PhylomeDB; Q9FBP4; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0000986; F:bacterial-type cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q9FBP4.
DR   SWISS-2DPAGE; Q9FBP4.
KW   DNA-binding {ECO:0000256|SAAS:SAAS01096662};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001973};
KW   Transcription {ECO:0000256|SAAS:SAAS01096725};
KW   Transcription regulation {ECO:0000256|SAAS:SAAS01096646}.
FT   DOMAIN          8..65
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   312 AA;  33161 MW;  41C984C9DEFD44C6 CRC64;
     MSSKKRQPSL AQLRAFDAVA EHLHFRDAAA AIGMSQPALS GAVSALEEAL GVTLLERTTR
     KVLLSPAGAR LAVRTKAVLA EVGALVEEAE AVRAPFTGAL RLGVIPTVAP YLLPTVLRLV
     HERYPDLDLQ VHEEQTASLL EGLTTGRLDL LLLAVPLGVP GVTELPLFDE DFVLVTPLDH
     RLGGREGLER SVLRELKLLL LDEGHCLRDQ ALDICREAGR AGVPATTTAA GLSTLVQLVA
     GGLGVTLLPR TAVRVETSRS SQLLTASFTD PAPTRRIALA MRTGAARSAE YGELAAALRE
     AMADLPVRTV HD
//

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