(data stored in ACNUC1104 zone)

SWISSPROT: DIM6_STRCO

ID   DIM6_STRCO              Reviewed;         177 AA.
AC   Q02058;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   08-MAY-2019, entry version 103.
DE   RecName: Full=Actinorhodin polyketide dimerase;
DE            EC=1.-.-.-;
DE   AltName: Full=actI ORF6;
GN   Name=actVB; OrderedLocusNames=SCO5092; ORFNames=SCBAC28G1.18;
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145;
RX   PubMed=1527048;
RA   Fernandez-Moreno M.A., Martinez E., Boto L., Hopwood D.A.,
RA   Malpartida F.;
RT   "Nucleotide sequence and deduced functions of a set of cotranscribed
RT   genes of Streptomyces coelicolor A3(2) including the polyketide
RT   synthase for the antibiotic actinorhodin.";
RL   J. Biol. Chem. 267:19278-19290(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145;
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H.,
RA   Harper D., Bateman A., Brown S., Chandra G., Chen C.W., Collins M.,
RA   Cronin A., Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S.,
RA   Huang C.-H., Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S.,
RA   Rabbinowitsch E., Rajandream M.A., Rutherford K.M., Rutter S.,
RA   Seeger K., Saunders D., Sharp S., Squares R., Squares S., Taylor K.,
RA   Warren T., Wietzorrek A., Woodward J.R., Barrell B.G., Parkhill J.,
RA   Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces
RT   coelicolor A3(2).";
RL   Nature 417:141-147(2002).
CC   -!- PATHWAY: Antibiotic biosynthesis; actinorhodin biosynthesis.
CC   -!- SIMILARITY: To S.pristinaespiralis SnaC. {ECO:0000305}.
DR   EMBL; X63449; CAA45048.1; -; Genomic_DNA.
DR   EMBL; AL939122; CAC44205.1; -; Genomic_DNA.
DR   PIR; S25845; S25845.
DR   RefSeq; NP_629242.1; NC_003888.3.
DR   RefSeq; WP_003973886.1; NC_003888.3.
DR   SMR; Q02058; -.
DR   STRING; 100226.SCO5092; -.
DR   PRIDE; Q02058; -.
DR   EnsemblBacteria; CAC44205; CAC44205; CAC44205.
DR   GeneID; 1100533; -.
DR   KEGG; sco:SCO5092; -.
DR   PATRIC; fig|100226.15.peg.5172; -.
DR   eggNOG; ENOG4105MXW; Bacteria.
DR   eggNOG; COG1853; LUCA.
DR   HOGENOM; HOG000115783; -.
DR   InParanoid; Q02058; -.
DR   KO; K14631; -.
DR   OMA; ALMYENS; -.
DR   PhylomeDB; Q02058; -.
DR   UniPathway; UPA00173; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0016646; F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor; IBA:GO_Central.
DR   GO; GO:0042602; F:riboflavin reductase (NADPH) activity; IBA:GO_Central.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006208; P:pyrimidine nucleobase catabolic process; IBA:GO_Central.
DR   Gene3D; 2.30.110.10; -; 1.
DR   InterPro; IPR002563; Flavin_Rdtase-like_dom.
DR   InterPro; IPR012349; Split_barrel_FMN-bd.
DR   Pfam; PF01613; Flavin_Reduct; 1.
DR   SMART; SM00903; Flavin_Reduct; 1.
PE   4: Predicted;
DR   PRODOM; Q02058.
DR   SWISS-2DPAGE; Q02058.
KW   Antibiotic biosynthesis; Complete proteome; Oxidoreductase;
KW   Reference proteome.
FT   CHAIN         1    177       Actinorhodin polyketide dimerase.
FT                                /FTId=PRO_0000079899.
SQ   SEQUENCE   177 AA;  18393 MW;  D3749EF33F2BB3C6 CRC64;
     MAADQGMLRD AMARVPAGVA LVTAHDRGGV PHGFTASSFV SVSMEPPLAL VCLARTANSF
     PVFDSCGEFA VSVLREDHTD LAMRFARKSA DKFAGGEFVR TARGATVLDG AVAVVECTVH
     ERYPAGDHII LLGEVQSVHV EEKGVPAVYV DRRFAALCSA AGACPSATGR GVPAHAG
//

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