(data stored in ACNUC1104 zone)

SWISSPROT: Q9EWF1_STRCO

ID   Q9EWF1_STRCO            Unreviewed;       346 AA.
AC   Q9EWF1;
DT   01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2001, sequence version 1.
DT   08-MAY-2019, entry version 115.
DE   SubName: Full=Putative dehydrogenase {ECO:0000313|EMBL:CAD30931.1};
GN   OrderedLocusNames=SCO4945 {ECO:0000313|EMBL:CAD30931.1};
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226 {ECO:0000313|Proteomes:UP000001973};
RN   [1] {ECO:0000313|EMBL:CAD30931.1, ECO:0000313|Proteomes:UP000001973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145
RC   {ECO:0000313|Proteomes:UP000001973};
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H.,
RA   Harper D., Bateman A., Brown S., Chandra G., Chen C.W., Collins M.,
RA   Cronin A., Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S.,
RA   Huang C.H., Kieser T., Larke L., Murphy L., Oliver K., O'Neil S.,
RA   Rabbinowitsch E., Rajandream M.A., Rutherford K., Rutter S.,
RA   Seeger K., Saunders D., Sharp S., Squares R., Squares S., Taylor K.,
RA   Warren T., Wietzorrek A., Woodward J., Barrell B.G., Parkhill J.,
RA   Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces
RT   coelicolor A3(2).";
RL   Nature 417:141-147(2002).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|RuleBase:RU361277}.
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DR   EMBL; AL939122; CAD30931.1; -; Genomic_DNA.
DR   RefSeq; NP_629097.1; NC_003888.3.
DR   RefSeq; WP_003974028.1; NC_003888.3.
DR   STRING; 100226.SCO4945; -.
DR   PRIDE; Q9EWF1; -.
DR   EnsemblBacteria; CAD30931; CAD30931; CAD30931.
DR   GeneID; 1100386; -.
DR   KEGG; sco:SCO4945; -.
DR   PATRIC; fig|100226.15.peg.5025; -.
DR   eggNOG; ENOG4105DQ4; Bacteria.
DR   eggNOG; COG1064; LUCA.
DR   HOGENOM; HOG000294667; -.
DR   InParanoid; Q9EWF1; -.
DR   KO; K13979; -.
DR   OMA; YRFSIDM; -.
DR   PhylomeDB; Q9EWF1; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IBA:GO_Central.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   InterPro; IPR013149; ADH_C.
DR   InterPro; IPR013154; ADH_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; SSF50129; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q9EWF1.
DR   SWISS-2DPAGE; Q9EWF1.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001973};
KW   Metal-binding {ECO:0000256|RuleBase:RU361277};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001973};
KW   Zinc {ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN       14    341       PKS_ER. {ECO:0000259|SMART:SM00829}.
SQ   SEQUENCE   346 AA;  36494 MW;  6705F599F4696CC4 CRC64;
     MTTVAAYAAP AAKAPLERTT IERREVREHD VLIDIKFAGI CHSDIHQARE GWGEAIFPMV
     PGHEIAGIVS EVGPGVTRFK VGDRVGVGCM VDSCRECENC KAGREQYCTS GNTGTYNAVG
     RDGEVTYGGY SEKVVVDENF VLGIPEGIAL DEAAPLLCAG ITTYSPLKRW NAGPGKKVAV
     VGLGGLGHMA VKLAHALGAE VTVLSQSLRK KDDGLKLGAD HYYATSDPAT FEELSGTFDL
     IVSTVSAPLD LGAYLGLLKT EGTLANVGAP EEPVSLNLFA LLGGGKSLSG SMIGGIAETQ
     EMLDFCAEHG IGAEIELIAA SEINEAYERV LSSDVRYRFV IDTATI
//

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