(data stored in ACNUC1104 zone)

SWISSPROT: Q9EWG3_STRCO

ID   Q9EWG3_STRCO            Unreviewed;       409 AA.
AC   Q9EWG3;
DT   01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2001, sequence version 1.
DT   11-DEC-2019, entry version 102.
DE   SubName: Full=L-threonine ammonia-lyase {ECO:0000313|EMBL:TYP03682.1};
DE   SubName: Full=Putative amino acid deaminase {ECO:0000313|EMBL:CAD30948.1};
GN   OrderedLocusNames=SCO4962 {ECO:0000313|EMBL:CAD30948.1};
GN   ORFNames=FHV98_12743 {ECO:0000313|EMBL:TYP03682.1};
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226 {ECO:0000313|Proteomes:UP000001973};
RN   [1] {ECO:0000313|EMBL:CAD30948.1, ECO:0000313|Proteomes:UP000001973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A3 {ECO:0000313|EMBL:CAD30948.1}, and ATCC BAA-471 / A3(2) /
RC   M145 {ECO:0000313|Proteomes:UP000001973};
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA   Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
RN   [2] {ECO:0000313|EMBL:TYP03682.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ICSSB 1010 {ECO:0000313|EMBL:TYP03682.1};
RA   Yuzawa S.;
RT   "Genome sequencing of Streptomyces strains engineered using actinophage
RT   integration system.";
RL   Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AL939122; CAD30948.1; -; Genomic_DNA.
DR   EMBL; VNID01000027; TYP03682.1; -; Genomic_DNA.
DR   RefSeq; NP_629114.1; NC_003888.3.
DR   RefSeq; WP_011029975.1; NC_003888.3.
DR   STRING; 100226.SCO4962; -.
DR   EnsemblBacteria; CAD30948; CAD30948; CAD30948.
DR   GeneID; 1100403; -.
DR   KEGG; sco:SCO4962; -.
DR   PATRIC; fig|100226.15.peg.5042; -.
DR   eggNOG; ENOG4105C7B; Bacteria.
DR   eggNOG; COG1171; LUCA.
DR   HOGENOM; HOG000046972; -.
DR   InParanoid; Q9EWG3; -.
DR   KO; K01754; -.
DR   OMA; LIHPFDH; -.
DR   PhylomeDB; Q9EWG3; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0003941; F:L-serine ammonia-lyase activity; IBA:GO_Central.
DR   GO; GO:0004794; F:L-threonine ammonia-lyase activity; IBA:GO_Central.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006565; P:L-serine catabolic process; IBA:GO_Central.
DR   GO; GO:0006567; P:threonine catabolic process; IBA:GO_Central.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR001926; PLP-dep.
DR   InterPro; IPR000634; Ser/Thr_deHydtase_PyrdxlP-BS.
DR   InterPro; IPR005789; Thr_deHydtase_catblc.
DR   InterPro; IPR036052; Trypto_synt_PLP_dependent.
DR   Pfam; PF00291; PALP; 1.
DR   SUPFAM; SSF53686; SSF53686; 1.
DR   TIGRFAMs; TIGR01127; ilvA_1Cterm; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00165; DEHYDRATASE_SER_THR; 1.
PE   4: Predicted;
DR   PRODOM; Q9EWG3.
DR   SWISS-2DPAGE; Q9EWG3.
KW   Lyase {ECO:0000313|EMBL:TYP03682.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001973}.
FT   DOMAIN          336..409
FT                   /note="ACT"
FT                   /evidence="ECO:0000259|PROSITE:PS51671"
SQ   SEQUENCE   409 AA;  42280 MW;  9F21A40D3ECEA9B9 CRC64;
     MSYSTASCVA PVTLDDVRGA QKMLSGVARV TAMEGSRHLS QLVGSPVHLK CENLQRTGSF
     KLRGAYVRIA GLLPEQRAAG VVAASAGNHA QGVALASSLL GVRSTVFMPQ GAPLPKISAT
     RDYGAEVRLH GQVVDETLAA AQEYAERTGA VFIHPFDHPD VIAGQGTVGL EILEQCPEVR
     TVVVGIGGGG LAAGIAVAVK ALRPDVRIVG VQAEGAAAYP PSLAAGRPVA VQNPATMADG
     IKVGRPGDVP FGIVGELVDE VRTVSEDALS TALLLCLERA KLVVEPAGAS PVAALLSEPD
     AFEGPVVAVL SGGNVDPVLM QGVLRHGMAA QGRYLAVRLR LTDRPGALAT LLGVLSVVDA
     NVLDVSHVRT HPRLGLTEAE VELHLETKGP EHCTEVGRVL REAGYTVIA
//

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