(data stored in ACNUC9543 zone)

SWISSPROT: Q8IBC3_PLAF7

ID   Q8IBC3_PLAF7            Unreviewed;       272 AA.
AC   Q8IBC3;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   11-DEC-2019, entry version 84.
DE   RecName: Full=Prohibitin {ECO:0000256|RuleBase:RU366048};
GN   ORFNames=PF3D7_0829200 {ECO:0000313|EMBL:CAD51083.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD51083.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA   Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA   Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA   Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA   Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA   Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA   Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA   Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA   Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA   Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA   Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000256|RuleBase:RU366048}.
CC   -!- SIMILARITY: Belongs to the prohibitin family.
CC       {ECO:0000256|RuleBase:RU366048}.
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DR   EMBL; AL844507; CAD51083.1; -; Genomic_DNA.
DR   RefSeq; XP_001349234.1; XM_001349198.1.
DR   SMR; Q8IBC3; -.
DR   PRIDE; Q8IBC3; -.
DR   EnsemblProtists; CAD51083; CAD51083; PF3D7_0829200.
DR   GeneDB; PF3D7_0829200.1:pep; -.
DR   GeneID; 2655455; -.
DR   KEGG; pfa:PF3D7_0829200; -.
DR   EuPathDB; PlasmoDB:PF3D7_0829200; -.
DR   HOGENOM; HOG000205692; -.
DR   InParanoid; Q8IBC3; -.
DR   KO; K17080; -.
DR   OMA; RTRIRDN; -.
DR   PhylomeDB; Q8IBC3; -.
DR   BioCyc; PLASMO:PF08_0006-MONOMER; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042127; P:regulation of cell population proliferation; ISS:GeneDB.
DR   CDD; cd03401; SPFH_prohibitin; 1.
DR   InterPro; IPR001107; Band_7.
DR   InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR   InterPro; IPR000163; Prohibitin.
DR   PANTHER; PTHR23222; PTHR23222; 1.
DR   Pfam; PF01145; Band_7; 1.
DR   PRINTS; PR00679; PROHIBITIN.
DR   SMART; SM00244; PHB; 1.
DR   SUPFAM; SSF117892; SSF117892; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q8IBC3.
DR   SWISS-2DPAGE; Q8IBC3.
KW   Membrane {ECO:0000256|RuleBase:RU366048};
KW   Mitochondrion {ECO:0000256|RuleBase:RU366048};
KW   Mitochondrion inner membrane {ECO:0000256|RuleBase:RU366048};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT   DOMAIN          25..186
FT                   /note="PHB"
FT                   /evidence="ECO:0000259|SMART:SM00244"
SQ   SEQUENCE   272 AA;  30558 MW;  F9A5F55AC12D1B76 CRC64;
     MERILSSIGK LSVVAGGLSL IPYTFIYDVD GGERCVMFNR FGGVSENTFG EGSHFYVPWF
     QTPYIYDIKM KPKVINTTTG TRDLQIVTIS LRLLFRPHTQ HLPYLHSTLG PDYDERVLPS
     IGNEVLKAVV AKYNAESLLT QRDKISKEIR ESITARAKHF NILLDDVAIT HLSYGKEFAK
     AIEDKQVAQQ ESERVKFIVA KTEQEKIAAV IKAQGEAEAA KLISSAVKEY GKSLIEIRKL
     EAAKEIAENL SKSKNVTYFP SNSNILLNPR DF
//

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