(data stored in ACNUC9543 zone)

SWISSPROT: YPF15_PLAF7

ID   YPF15_PLAF7             Reviewed;        1033 AA.
AC   Q8IBB8;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   11-DEC-2019, entry version 66.
DE   RecName: Full=Uncharacterized protein MAL8P1.12 {ECO:0000312|EMBL:CAD51088.1};
GN   ORFNames=MAL8P1.12;
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7;
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000312|EMBL:CAD51088.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7;
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA   Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA   Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA   Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA   Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA   Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA   Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA   Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA   Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA   Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA   Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
RN   [3] {ECO:0000305}
RP   SYNTHESIS OF 860-914, AND POSSIBLE CANDIDATE MALARIA EPITOPE.
RX   PubMed=17653272; DOI=10.1371/journal.pone.0000645;
RA   Villard V., Agak G.W., Frank G., Jafarshad A., Servis C., Nebie I.,
RA   Sirima S.B., Felger I., Arevalo-Herrera M., Herrera S., Heitz F.,
RA   Baecker V., Druilhe P., Kajava A.V., Corradin G.;
RT   "Rapid identification of malaria vaccine candidates based on alpha-helical
RT   coiled coil protein motif.";
RL   PLoS ONE 2:E645-E645(2007).
CC   -!- BIOTECHNOLOGY: Possible candidate for an effective malaria vaccine as
CC       determined by epitope response in sera. {ECO:0000269|PubMed:17653272}.
DR   EMBL; AL844507; CAD51088.1; -; Genomic_DNA.
DR   RefSeq; XP_001349239.1; XM_001349203.1.
DR   SMR; Q8IBB8; -.
DR   BioGrid; 1210092; 1.
DR   IntAct; Q8IBB8; 1.
DR   PRIDE; Q8IBB8; -.
DR   EnsemblProtists; CAD51088; CAD51088; PF3D7_0828700.
DR   GeneDB; PF3D7_0828700.1:pep; -.
DR   GeneID; 2655240; -.
DR   KEGG; pfa:PF3D7_0828700; -.
DR   EuPathDB; PlasmoDB:PF3D7_0828700; -.
DR   HOGENOM; HOG000282575; -.
DR   InParanoid; Q8IBB8; -.
DR   KO; K23729; -.
DR   OMA; TQIKIKQ; -.
DR   PhylomeDB; Q8IBB8; -.
DR   BioCyc; PLASMO:MAL8P1.12-MONOMER; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0005930; C:axoneme; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; NAS:UniProtKB.
DR   GO; GO:0003341; P:cilium movement; IBA:GO_Central.
DR   GO; GO:0060285; P:cilium-dependent cell motility; IBA:GO_Central.
DR   GO; GO:0036159; P:inner dynein arm assembly; IBA:GO_Central.
DR   InterPro; IPR033290; CCDC39.
DR   PANTHER; PTHR18962; PTHR18962; 1.
PE   1: Evidence at protein level;
DR   PRODOM; Q8IBB8.
DR   SWISS-2DPAGE; Q8IBB8.
KW   Coiled coil; Merozoite; Reference proteome.
FT   CHAIN           1..1033
FT                   /note="Uncharacterized protein MAL8P1.12"
FT                   /id="PRO_0000388768"
FT   COILED          212..326
FT                   /evidence="ECO:0000255"
FT   COILED          405..582
FT                   /evidence="ECO:0000255"
FT   COILED          615..771
FT                   /evidence="ECO:0000255"
FT   COILED          797..1019
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        159..866
FT                   /note="Lys-rich"
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        861..983
FT                   /note="Asn-rich"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1033 AA;  123778 MW;  7BF0F2F91F2182FE CRC64;
     MSEESFDDTN KAFENEKDII LEKIVKDENN LNNCSNMINM DDVENMKKEL YVLHKKDEEI
     ENNVDCFSGD KYNVENVINL KKKKKKDEDT DSSYYKTTLD EVYDTSDIST DEMLSNYSSS
     EDNNNIEMNI INDFYLKDDN TYCLEWNSDI INVLSEEIKE KEKLLEDENK DICNMKSRFL
     KLEKYVNIKK KKIINIKKNI EEKRKIEFDE KEIFKCLQIK NDFLKKENKK IELEREKNNK
     KIIETQNNIT TCQKNIDDIK KELILKENEL NDFINKIKII QQEEYEIEKI KLSKDKEIQN
     VSYNLEKYNN EKIQQDKKYE QVKMNNMKFD IELKSIIQEY YDIKKDIKNI SNKYICIMDM
     IKCRDKTIYK FEKDYTKTIH KEKQLQNKCL HKQNLINTQK DKNIILNNQI KKIQFDINKI
     RKELNDKQMS YDKTIIDRDH LNKEYEYEIV EIKEKLQEEK KSLENTLQHL NETYITMSTN
     YEESKNEYEK EQVNNIEKND LIKSSEQILV QLQNKLQKLL DEIKSLDLEK FQLTQTLQVI
     KNDYITLEAD VLGTQIKIKQ IKSNIKKTEK ELERQKEMLY KFDFQTQVLT KKINMISGIS
     TFEKKKENQK KIILLEKELY KNEDIYNTLN NEMKRINIEI KNIKLYQNEL QEQKMNYKNL
     YEKLQLEIKS LESTINNEIK EKENIMLIEL NLKIELDKLK STFSKHVDNL NICKKEKKEN
     MNNAKLSEQD INAHMESLKV IIKNINDEIH KLNIQLYEKK NKSNNLQLKL NSIIICNQKN
     KDQKDICPNE NQHIYYKMKI DQDIINLKEQ LKKINEQIDK ENIETKNFQR TLDDIIQTNK
     EFNDNIKSID PQYKILLKKK NKLNKKWEQI NDHINNLETN INDYNKKIKE GDSQLNNIQL
     QCENIEQKIN KIKESNLKVE NNINDLFIKI ERASNQLKKN LAPTTNMMKL KNKQIKDDEN
     NLSNNNNNNN NNNNNINVNV NVNCEPVPLE KHIFKQIQME SLKEKLSLLM ECFKNNIDNV
     IMKEVFNLIE TAE
//

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