(data stored in ACNUC9543 zone)

SWISSPROT: Q8IBA2_PLAF7

ID   Q8IBA2_PLAF7            Unreviewed;      1289 AA.
AC   Q8IBA2;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   08-MAY-2019, entry version 105.
DE   SubName: Full=ATP-dependent RNA helicase DBP10, putative {ECO:0000313|EMBL:CAD51105.1};
DE            EC=3.6.3.- {ECO:0000313|EMBL:CAD51105.1};
GN   ORFNames=PF3D7_0827000 {ECO:0000313|EMBL:CAD51105.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD51105.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA   Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S.,
RA   Chan M.S., Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S.,
RA   Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B.,
RA   Martin D.M., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A.,
RA   McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C.,
RA   Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W.,
RA   Fraser C.M., Barrell B.;
RT   "Genome sequence of the human malaria parasite Plasmodium
RT   falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C.,
RA   Chillingworth T., Christodoulou Z., Clark L., Clark R., Corton C.,
RA   Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J.,
RA   Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z.,
RA   Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P.,
RA   Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A.,
RA   Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N.,
RA   Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L.,
RA   Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E.,
RA   Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M.,
RA   Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K.,
RA   Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AL844507; CAD51105.1; -; Genomic_DNA.
DR   RefSeq; XP_001349256.1; XM_001349220.1.
DR   SMR; Q8IBA2; -.
DR   IntAct; Q8IBA2; 1.
DR   EnsemblProtists; CAD51105; CAD51105; PF3D7_0827000.
DR   GeneDB; PF3D7_0827000.1:pep; -.
DR   GeneID; 2655364; -.
DR   KEGG; pfa:PF3D7_0827000; -.
DR   EuPathDB; PlasmoDB:PF3D7_0827000; -.
DR   HOGENOM; HOG000282591; -.
DR   InParanoid; Q8IBA2; -.
DR   KO; K14808; -.
DR   OMA; DNYCGDN; -.
DR   BioCyc; PLASMO:MAL8P1.19-MONOMER; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd00079; HELICc; 1.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR   InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS51195; Q_MOTIF; 1.
PE   4: Predicted;
DR   PRODOM; Q8IBA2.
DR   SWISS-2DPAGE; Q8IBA2.
KW   ATP-binding {ECO:0000313|EMBL:CAD51105.1};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001450};
KW   Helicase {ECO:0000313|EMBL:CAD51105.1};
KW   Hydrolase {ECO:0000313|EMBL:CAD51105.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:CAD51105.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT   DOMAIN      159    188       Q_MOTIF. {ECO:0000259|PROSITE:PS51195}.
FT   DOMAIN      191    365       Helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51192}.
FT   DOMAIN      392    547       Helicase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51194}.
FT   COILED      882    913       {ECO:0000256|SAM:Coils}.
FT   COILED      976   1004       {ECO:0000256|SAM:Coils}.
FT   MOTIF       159    188       Q motif. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00552}.
SQ   SEQUENCE   1289 AA;  151105 MW;  2E4139A8B3CA3FB5 CRC64;
     MKNKKKLFGP SSSNNTKSNK KKINKSKNKS KSKKNEKNEK RINIKKNNGL KKSKEDVSKR
     KDIDLLQNNK KKNILIKTNK NISKNKNGTK RYQWLFSDKD KKKEKVEESD LNNYSSSCSY
     DDKKKEKKKF VLYKKKKNKS NNNSNNSNNK KKKKKVILNS FQQLGLSENM CRSIASNLKY
     NKPTNIQKLC ITKILHRRDV ICISKTGSGK SLVYLCTLID ILKEHNKYYG IRGLIILPTK
     ELVIQIYKLC KKICKNYFHL NINIIIGGVS IIKQFDILNQ NLDILLCTPG RLSFLLQETK
     LSLEKVEILI IDEADRLLEL NYYNDMNVIY KSLNNTSKQT ILVSATLPTN VENYFKLKLN
     NPDVLFLTSD NTINEKVHLH FLFCRSYEKY ALLLRLILIF KKKKLGKTMI FFCTKYHILF
     FSNILKHFKI HHSILYGNSD TSFRFEQINN FTKNEHIQFL LVTDVASRGI NITSVQNVIN
     YNLPFSPKLF IHRIGRACRT DISGYGISLL TYQDILYAYE ICFFIGKKLK FFKKEKSVLD
     NDMEDISSKG FTSKGMDIEA NTVVNEMSNV TNMNNDNDNK CGDNECGDNK CGDNECGDNK
     CGDNKCGDNY CGDNYCGDNY CGDNECVDKV YYGDDKNKRD KSYTCSHKNN TNDIVYMGCV
     PHLNDYIEYI EDLKKRDTEL MSLNKSILAS YKLYYSMRPK VSKYVSTKCI NKINKIGGLY
     KLSLYNHPHW IYENERCLPE DMRSTNENTT HEFLENEKEM DYTNDCVNNN NNNNNNNNNN
     NNNNDNNDGD VYMCNDQLND EVDILFNNLI NYISHNNNNN NISNENITND LVQNEIKSDD
     QENDTTEIQN NEHYEESNIE NVNANYDYSK NKLISIIHNF ENKNSNNKIK TISDELKQKL
     NQLKEKNERY KSRRNYVLSN DVNEFMDTLT YQISDEEDEN ADIKNIPEMW KKIFLHSQGN
     NNSTSMNIND PSEHYMENKK KLSKRALKKL KKNENNDSNE FNNNNNINNN DNVNNIKNIS
     FDDVLRIINE KKMKNDMRYN NTSTLDIKNP GFDLPPDETE ELNKQRFVKK QIWDKKKRKF
     VLTEIDTFQT DEFGIKKKVN KNKDDKTNSI TNLYEKWVKS TKKRIKNVGE LEDENDIIPK
     TKLNKNKNKN KKGKKNKNQN KYNNDISDNN DNNSENEEKQ YNINMLKLMH PEISEALSKN
     NKLTKKQQRI YKKYISGKYI NATTQKDTNT LHNTAKQRKK QLQNRLRTDK KFRTKYLKIK
     KKKFENKMKR KHNLSSARER SLIILKNKK
//

If you have problems or comments...

PBIL Back to PBIL home page