(data stored in SCRATCH zone)

SWISSPROT: Q8IB33_PLAF7

ID   Q8IB33_PLAF7            Unreviewed;      1408 AA.
AC   Q8IB33;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   11-DEC-2019, entry version 95.
DE   RecName: Full=TPR_REGION domain-containing protein {ECO:0000259|PROSITE:PS50293};
GN   ORFNames=PF3D7_0819800 {ECO:0000313|EMBL:CAD51176.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD51176.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA   Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA   Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA   Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA   Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA   Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA   Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA   Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA   Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA   Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA   Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
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DR   EMBL; AL844507; CAD51176.1; -; Genomic_DNA.
DR   RefSeq; XP_001349327.1; XM_001349291.1.
DR   SMR; Q8IB33; -.
DR   EnsemblProtists; CAD51176; CAD51176; PF3D7_0819800.
DR   GeneDB; PF3D7_0819800.1:pep; -.
DR   GeneID; 2655343; -.
DR   KEGG; pfa:PF3D7_0819800; -.
DR   EuPathDB; PlasmoDB:PF3D7_0819800; -.
DR   HOGENOM; HOG000282652; -.
DR   InParanoid; Q8IB33; -.
DR   OMA; TIQFYKP; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR040163; RP1/RP1L1/DCX.
DR   InterPro; IPR013026; TPR-contain_dom.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR23005; PTHR23005; 9.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   PROSITE; PS50293; TPR_REGION; 1.
PE   4: Predicted;
DR   PRODOM; Q8IB33.
DR   SWISS-2DPAGE; Q8IB33.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT   DOMAIN          1241..1311
FT                   /note="TPR_REGION"
FT                   /evidence="ECO:0000259|PROSITE:PS50293"
FT   REGION          120..150
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          761..816
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1021..1074
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1089..1144
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          398..418
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          883..903
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          913..933
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          986..1006
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        761..813
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1089..1121
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1122..1139
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1408 AA;  170278 MW;  A64274BFAED5F349 CRC64;
     MEYKEKPEGP FFVSFYVTNF NSSDQSFSYK INIVDFYDNL YESNIINQNN FKQINFSNNY
     IQLNEEIFVK TNISDDNNFV LIGYENIKVF SFLHEQLIIS KNIIITYKYE DQKENVVNKN
     IDNEKNKKTK DNEKEGKNKK KKEKNKNNAK NEMEILENSI KKDIDINFNI TLNINSLVGH
     YCDRLNYNIM NVKIDGIYNI SSSIEEIVPK RNSLNFHMKL LDISLYNGIP IEDKENKKYN
     ITWNNNNIYK YRNIKEIEYI YKYLFYESFN VNGWIICFNE NKKTKDNVTS SIVDTLCATF
     EVNISDVILN KVVNAKYKLH HIKHLKKDIK NVKQSGNQCL DIFTNSYIQL TIQFYKPFLQ
     RKMLESPFAV NTVRPNLKKE IQIENDKKQK EDISNLFNRS VMEGIKFVND EIKQLRKEEQ
     IKIYQRSKEY FSFLNNLKEN PKYINLYNNM KDVMIKVTYN IINKKIYKHF NISEELCMDP
     SSDNDDMMDK DKKKKEKSDF ISEENINCIF VYLFNFMYES SNVIINNYFE KEDNIYKESI
     NDIKKYNNIN NLEYYLYNII IENVHLLKYE RNIPFIQAII LILYKKINYV YERNIKEKNI
     NDIFIQKGDN HIINIIENYT GYDDNNTLED NYIYKKKKIN EKKNVYSNNP ENNITSLINH
     ICTRNQSNFN SYLFDYIEHF KDIILHKHVI KEDEEIFKRN DHQEDILSVF NMEENKNIKI
     MFTDIIYMYS NVMLLKNNII NLKYDKERQI RKYREENEAN KINEENKENE KNEENKEDEK
     NEENKDEKNE ENKEDEKNEE NKEDEKNEEN NYYDDNHNYN FQVNFDYYDT YINSNIVDTS
     ISCLCTYIEL TNSENIESLF ILCLLYLNIH KYKESLKLAN YIINILQKRK ENEEEIKNKV
     QDKVQDNVED NVEDNVEDNV EDKIEEKLKE KEEEDHLNIN NLYIYSTLHN NHLNICENIC
     IYIKSLCYFF QRNYIYYYIN MCILLNENLN TLKECIEKNS NLYEEEKEKC FDSRKCNNKE
     SKKKEKKDIE KDHKEKKKGS KKKIKDENNE MKDIQNEEMD MKKNEMDKKK DQMDIKKNEV
     DIQNEEISIQ DEQICNQDEQ SQNTYNSDKN NNNYNKNVYD NTNISRRKDK SKENSSFKNV
     KSKSEISPCH TDNYILNYIE SSENKIPLKD KYMLLFIIYC LKYNIINIVM FIYENRRKLL
     TDMAINSHLF HHLTIKIFFS IKDYLRCTNL IEEKCEHLNN VDILYIYTQC LYKLKSYEKC
     IGYMEKYLNL CKYNNVRVKI YLQLNKIYFS LNRYSESKSM IKNSLQIYKT SYAYLNLAYY
     YLIKKKNFIY AYKILYKANE INIFNTKLWA YFTVVFLHLN MKMQADKSLN NFLKMNMYKK
     NLIIHMMETY KFYGYEKEEK YLLSFLKN
//

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