(data stored in ACNUC9543 zone)

SWISSPROT: Q8IB14_PLAF7

ID   Q8IB14_PLAF7            Unreviewed;        99 AA.
AC   Q8IB14;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   11-DEC-2019, entry version 115.
DE   SubName: Full=High mobility group protein B2 {ECO:0000313|EMBL:CAD51195.1};
GN   ORFNames=PF3D7_0817900 {ECO:0000313|EMBL:CAD51195.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD51195.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA   Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA   Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA   Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA   Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA   Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA   Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA   Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA   Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA   Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA   Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
RN   [3] {ECO:0000213|PDB:2MRC}
RP   STRUCTURE BY NMR OF 17-99.
RA   Tang C., Barnwal R., Varani G.;
RT   "NMR Structure and 1H, 13C and 15N Chemical Shift Assignments for High
RT   mobility group protein from Plasmodium falciparum 3D7.";
RL   Submitted (JUL-2014) to the PDB data bank.
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DR   EMBL; AL844507; CAD51195.1; -; Genomic_DNA.
DR   RefSeq; XP_001349346.1; XM_001349310.2.
DR   PDB; 2MRC; NMR; -; A=17-99.
DR   PDBsum; 2MRC; -.
DR   SMR; Q8IB14; -.
DR   IntAct; Q8IB14; 2.
DR   PRIDE; Q8IB14; -.
DR   EnsemblProtists; CAD51195; CAD51195; PF3D7_0817900.
DR   GeneDB; PF3D7_0817900.1:pep; -.
DR   GeneID; 2655422; -.
DR   KEGG; pfa:PF3D7_0817900; -.
DR   EuPathDB; PlasmoDB:PF3D7_0817900; -.
DR   HOGENOM; HOG000197861; -.
DR   InParanoid; Q8IB14; -.
DR   OMA; KRWETIS; -.
DR   PhylomeDB; Q8IB14; -.
DR   BioCyc; PLASMO:MAL8P1.72-MONOMER; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0005694; C:chromosome; IDA:GeneDB.
DR   GO; GO:0005829; C:cytosol; IDA:GeneDB.
DR   GO; GO:0000790; C:nuclear chromatin; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IDA:GeneDB.
DR   GO; GO:0008301; F:DNA binding, bending; IDA:GeneDB.
DR   GO; GO:0002720; P:positive regulation of cytokine production involved in immune response; IDA:GeneDB.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   GO; GO:0006359; P:regulation of transcription by RNA polymerase III; ISS:GeneDB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:GeneDB.
DR   Gene3D; 1.10.30.10; -; 1.
DR   InterPro; IPR009071; HMG_box_dom.
DR   InterPro; IPR036910; HMG_box_dom_sf.
DR   Pfam; PF00505; HMG_box; 1.
DR   SMART; SM00398; HMG; 1.
DR   SUPFAM; SSF47095; SSF47095; 1.
DR   PROSITE; PS50118; HMG_BOX_2; 1.
PE   1: Evidence at protein level;
DR   PRODOM; Q8IB14.
DR   SWISS-2DPAGE; Q8IB14.
KW   3D-structure {ECO:0000213|PDB:2MRC}; Coiled coil {ECO:0000256|SAM:Coils};
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00267,
KW   ECO:0000256|SAAS:SAAS00879239};
KW   Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT   DOMAIN          24..94
FT                   /note="HMG box"
FT                   /evidence="ECO:0000259|PROSITE:PS50118"
FT   DNA_BIND        24..94
FT                   /note="HMG box"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          76..99
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        8..22
FT                   /note="Basic"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   99 AA;  11535 MW;  B5E3F00B533E9163 CRC64;
     MASKSQKKVL KKQNKKKKKD PLAPKRALSA YMFYVKDKRL EIIKEKPELA KDVAQVGKLI
     GEAWGQLSPA QKAPYEKKAQ LDKVRYSKEI EEYRKKNQE
//

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