(data stored in SCRATCH zone)

SWISSPROT: Q8IAY0_PLAF7

ID   Q8IAY0_PLAF7            Unreviewed;       679 AA.
AC   Q8IAY0;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   11-DEC-2019, entry version 84.
DE   SubName: Full=Phospholipase DDHD1, putative {ECO:0000313|EMBL:CAD51230.1};
DE            EC=3.1.1.32 {ECO:0000313|EMBL:CAD51230.1};
GN   ORFNames=PF3D7_0814400 {ECO:0000313|EMBL:CAD51230.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD51230.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA   Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA   Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA   Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA   Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA   Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA   Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA   Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA   Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA   Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA   Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
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DR   EMBL; AL844507; CAD51230.1; -; Genomic_DNA.
DR   RefSeq; XP_001349381.1; XM_001349345.1.
DR   EnsemblProtists; CAD51230; CAD51230; PF3D7_0814400.
DR   GeneDB; PF3D7_0814400.1:pep; -.
DR   GeneID; 2655442; -.
DR   KEGG; pfa:PF3D7_0814400; -.
DR   EuPathDB; PlasmoDB:PF3D7_0814400; -.
DR   HOGENOM; HOG000280936; -.
DR   InParanoid; Q8IAY0; -.
DR   OMA; INFYEEE; -.
DR   Reactome; R-PFA-1483166; Synthesis of PA.
DR   Reactome; R-PFA-1483226; Synthesis of PI.
DR   Reactome; R-PFA-204005; COPII-mediated vesicle transport.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0052740; F:1-acyl-2-lysophosphatidylserine acylhydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0052739; F:phosphatidylserine 1-acylhydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008970; F:phospholipase A1 activity; IEA:UniProtKB-EC.
DR   GO; GO:0004620; F:phospholipase activity; IBA:GO_Central.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR004177; DDHD_dom.
DR   Pfam; PF02862; DDHD; 1.
DR   SMART; SM01127; DDHD; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
DR   PROSITE; PS51043; DDHD; 1.
PE   4: Predicted;
DR   PRODOM; Q8IAY0.
DR   SWISS-2DPAGE; Q8IAY0.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrolase {ECO:0000313|EMBL:CAD51230.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT   DOMAIN          222..607
FT                   /note="DDHD"
FT                   /evidence="ECO:0000259|PROSITE:PS51043"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          369..389
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   679 AA;  80761 MW;  4D7E9DC644083EF0 CRC64;
     MSNHTVKVED DDDENNEDTE KKVQSSFFFF KKQEKNVNRK FVKNTKDNDI NFYEDKPILD
     DKINKVDYII LIIHGIGSNE ELIINQCEDL KNSFKIVKKM WFFDYPFNIH FHIFNWKKYI
     IDAQIHVFNR ININTMAETR KIINLSAGDI ICFLHPRYGD YIMLNLYNDI NKTLESLKND
     SSGRFKYSKV CLLGYSLGSA MAYEILHNVK VRISESNLKY NLKSKIHYLF MLGSPLSALL
     SLYKPEYIND GLKLNNGLKF YNIFHGFDPV AFRIEPLIYP GIKNIPEPVL INYWRNNGAR
     YWFEWDKNMQ NAKLAIVQNL NDFTSAITNG FYKFLGKNEN NDEDQSTLNK NICYNKCESK
     DINIFLLKVK ENQRKIALQK KKIHRYNKKN NITYKENVAE KKNAHYNSIH NINDNNICDN
     ICDNICENIC DNICDNIRDN IRDNMRDNIR DNICDHHLND ISYNDEDSQD TYFGHEKYKR
     KYDHNDEQKK EGTYYSKEEN SSYIDSTKSI CASQDSNSEY SFFDHELSDN SNNLYEENRR
     NYDDHNKKRE SICNSNNIND ALNIRYDYQL QEFIMEHYIY PLAVAKSHFN YFIIKDISFF
     ILKELIHHKN ISLSYEEYLT KIEKEYNSKA LNEKDNIKKE KYFKVAIKAT KTLEEFKKYE
     KNIQAMSDPF NMKNFKNLI
//

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