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ID Q8IAX3_PLAF7 Unreviewed; 1419 AA.
AC Q8IAX3;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 08-MAY-2019, entry version 111.
DE SubName: Full=ABC transporter F family member 1, putative {ECO:0000313|EMBL:CAD51237.1};
GN ORFNames=PF3D7_0813700 {ECO:0000313|EMBL:CAD51237.1};
OS Plasmodium falciparum (isolate 3D7).
OC Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD51237.1, ECO:0000313|Proteomes:UP000001450};
RN [1] {ECO:0000313|Proteomes:UP000001450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX PubMed=12368864; DOI=10.1038/nature01097;
RA Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S.,
RA Chan M.S., Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S.,
RA Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B.,
RA Martin D.M., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A.,
RA McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C.,
RA Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W.,
RA Fraser C.M., Barrell B.;
RT "Genome sequence of the human malaria parasite Plasmodium
RT falciparum.";
RL Nature 419:498-511(2002).
RN [2] {ECO:0000313|Proteomes:UP000001450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX PubMed=12368867; DOI=10.1038/nature01095;
RA Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA Buckee C.O., Burrows C., Cherevach I., Chillingworth C.,
RA Chillingworth T., Christodoulou Z., Clark L., Clark R., Corton C.,
RA Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J.,
RA Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z.,
RA Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P.,
RA Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A.,
RA Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N.,
RA Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L.,
RA Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E.,
RA Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M.,
RA Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K.,
RA Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL Nature 419:527-531(2002).
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DR EMBL; AL844507; CAD51237.1; -; Genomic_DNA.
DR RefSeq; XP_001349388.1; XM_001349352.1.
DR IntAct; Q8IAX3; 2.
DR EnsemblProtists; CAD51237; CAD51237; PF3D7_0813700.
DR GeneDB; PF3D7_0813700.1:pep; -.
DR GeneID; 2655277; -.
DR KEGG; pfa:PF3D7_0813700; -.
DR EuPathDB; PlasmoDB:PF3D7_0813700; -.
DR HOGENOM; HOG000280939; -.
DR InParanoid; Q8IAX3; -.
DR KO; K15073; -.
DR OMA; SECVGLI; -.
DR BioCyc; PLASMO:PF08_0078-MONOMER; -.
DR Proteomes; UP000001450; Chromosome 8.
DR GO; GO:0020011; C:apicoplast; IEA:GeneDB.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 3.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
DR PRODOM; Q8IAX3.
DR SWISS-2DPAGE; Q8IAX3.
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00434};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Complete proteome {ECO:0000313|Proteomes:UP000001450};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00434};
KW Reference proteome {ECO:0000313|Proteomes:UP000001450};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1 20 {ECO:0000256|SAM:SignalP}.
FT CHAIN 21 1419 {ECO:0000256|SAM:SignalP}.
FT /FTId=PRO_5004308150.
FT DOMAIN 267 696 ABC transporter. {ECO:0000259|PROSITE:
FT PS50893}.
FT DOMAIN 971 1277 ABC transporter. {ECO:0000259|PROSITE:
FT PS50893}.
FT NP_BIND 299 306 ATP. {ECO:0000256|PROSITE-ProRule:
FT PRU00434}.
FT NP_BIND 1008 1015 ATP. {ECO:0000256|PROSITE-ProRule:
FT PRU00434}.
FT COILED 732 763 {ECO:0000256|SAM:Coils}.
FT COILED 861 901 {ECO:0000256|SAM:Coils}.
FT COILED 1145 1165 {ECO:0000256|SAM:Coils}.
FT COILED 1327 1347 {ECO:0000256|SAM:Coils}.
FT COILED 1363 1383 {ECO:0000256|SAM:Coils}.
SQ SEQUENCE 1419 AA; 170108 MW; 7E481EDAA8E3A0A8 CRC64;
MFLELYFYLI LCCYISFNSS LQVKKNNQYF LNSSYNRKGT SRPSRRKKNS FINKLFLAEH
VNTKKSTFRC YQQCKHKKNV ESGNDYMCDG VKKKRKKSGN NKKSDICHYD EDEEGIIAKP
YYDDYHRENR NDIQYDINED NNYEESDEDE LEEDEYEEEL EEDEYDEESD QDEYDEESDQ
DEYDEESDQD EYDEESDQDG YDEESNEDDL DEHLKERLMK RKSFYSKLFN IDDNEDKFNV
LSPKYNMNIY NILEKNYDQN EENQIVLTIK NLNYEINNRK LITNLNLQLN KTECIGLIGN
NGCGKTTLLN LIYENSDNKL KSFTLNNNIK KKEDAVSLNK FNLNTLSSSV KKNDFTLLYK
ILSYMKNNGI ELSNLPTLIQ NKTIHNILQE DNKDENNHNN NNNNNNNNKN NELFYKNEVF
YFKQNIHLLE NNNLTIFEKV LKFYDNTLEK YEILNYIEDN FGKYEKYDTI KIYGLKDNKR
NDEIEKRNHD ITKEDIKNDS SDIFITELNK NDQKLLKKSC MSSNQFNNVD TYGASNVLKN
NEEDFLKSEY FKLILKLYMH EKENIYKEIN NIKMNFNKYV NILNLKNFLN VKLCHLSNGY
IIRVYLLLLL LSKSKLLLID EINNNLDIFN IFFIMNIFKY SLKYKKLAII LATHDFFLVS
KLCNRILDFN KISGYDVDLS NMALLKKINK NNNHDDQDYG IYMDDMTNNR TNERKSNLTY
FKGNYTDYLN NMKILFENRK KKKEELKKIL DQINSVISKS KKKKKNEFIQ PFVKKKEEEL
KLYQNINSIL FDTKLDYQYL YYNLIYSNKK NTDTKARGKE KEKEKEKTMV TNLTFTNTQK
KNMDTEREDE INEKVDYESY SSDTNENVEE KEKNEKQKQQ QQQQKQQQQQ KQQQQKQTEQ
NVPEQNVPEQ KEQVDNNYDD DEDIKKFVYN KFNDVEGNMN KNILIDMSKK IKNNELIETG
EKYGTNNMPL YEFENFSFYF LNKNNKKKYI FKNMNLNINS GENVLLLGKN GIGKSTLFKI
LTNKYNFVLK EKENKLKEKK SIYVYGDNDD IMDTNFSNII NETNIENIKK NYNFEGTINC
NFKNVLLTYF EQNMIKKLNA EINDYFKNLV EKVNYEPISF YNSYNKNDDM ISNENFCFYI
LNKTKLLYNE KIDNIEEKIN KLLKIFFIDS NTSIKDKSGG EKVRILFLSL FLKKSNLLLL
DEINNNLDIY LKNLLLNFLN YIYQGSYILT THDFYIIKNL NNIHKIIYIF DYQNIFTFYN
VQDFIENFYN FILNSFNLCN AELKDHEYIQ KKRDKARLHN YSNYLNSQNI LQSNHLVQNN
IHLSSPYDTK KNDLINSEEN IDQLNNSANY QKYLYDNYDY EILQFLKKQF EKDNNERKNY
EQINIQEEIF QKKKINKKNF GGKGTSGKIK IKNWKRWKK
//
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