(data stored in SCRATCH zone)

SWISSPROT: Q8IAR6_PLAF7

ID   Q8IAR6_PLAF7            Unreviewed;       481 AA.
AC   Q8IAR6;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   11-DEC-2019, entry version 93.
DE   SubName: Full=26S proteasome regulatory subunit RPN10, putative {ECO:0000313|EMBL:CAD51294.1};
GN   ORFNames=PF3D7_0807800 {ECO:0000313|EMBL:CAD51294.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD51294.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA   Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA   Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA   Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA   Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA   Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA   Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA   Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA   Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA   Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA   Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL844507; CAD51294.1; -; Genomic_DNA.
DR   RefSeq; XP_001349445.1; XM_001349409.1.
DR   SMR; Q8IAR6; -.
DR   IntAct; Q8IAR6; 2.
DR   PRIDE; Q8IAR6; -.
DR   EnsemblProtists; CAD51294; CAD51294; PF3D7_0807800.
DR   GeneDB; PF3D7_0807800.1:pep; -.
DR   GeneID; 2655309; -.
DR   KEGG; pfa:PF3D7_0807800; -.
DR   EuPathDB; PlasmoDB:PF3D7_0807800; -.
DR   HOGENOM; HOG000283925; -.
DR   InParanoid; Q8IAR6; -.
DR   KO; K03029; -.
DR   OMA; DYNRNED; -.
DR   Reactome; R-PFA-1236978; Cross-presentation of soluble exogenous antigens (endosomes).
DR   Reactome; R-PFA-382556; ABC-family proteins mediated transport.
DR   Reactome; R-PFA-450408; AUF1 (hnRNP D0) binds and destabilizes mRNA.
DR   Reactome; R-PFA-5687128; MAPK6/MAPK4 signaling.
DR   Reactome; R-PFA-5689603; UCH proteinases.
DR   Reactome; R-PFA-5689880; Ub-specific processing proteases.
DR   Reactome; R-PFA-68949; Orc1 removal from chromatin.
DR   Reactome; R-PFA-69017; CDK-mediated phosphorylation and removal of Cdc6.
DR   Reactome; R-PFA-983168; Antigen processing: Ubiquitination & Proteasome degradation.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0008540; C:proteasome regulatory particle, base subcomplex; IBA:GO_Central.
DR   GO; GO:0031593; F:polyubiquitin modification-dependent protein binding; IBA:GO_Central.
DR   GO; GO:0043248; P:proteasome assembly; IBA:GO_Central.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   Gene3D; 3.40.50.410; -; 1.
DR   InterPro; IPR014624; 26S_protsm_s5a.
DR   InterPro; IPR027040; Proteasome_su_Rpn10.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR10223:SF0; PTHR10223:SF0; 1.
DR   Pfam; PF13519; VWA_2; 1.
DR   PIRSF; PIRSF036805; 26S_protsm_s5a; 1.
DR   SUPFAM; SSF53300; SSF53300; 1.
PE   4: Predicted;
DR   PRODOM; Q8IAR6.
DR   SWISS-2DPAGE; Q8IAR6.
KW   Proteasome {ECO:0000313|EMBL:CAD51294.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT   DOMAIN          7..115
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|Pfam:PF13519"
FT   REGION          279..354
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        284..354
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   481 AA;  55067 MW;  B65AE4015AC76177 CRC64;
     MSNIEATIIC IDNSDYNRNE DIVPNRFLSQ IDCVNVLCCN KTSLHYKNNI GILMMAGDKI
     KVKVSLTNDI GQLLSCIHDI KLDGTCDIIR SLLIAQLALK HRVDKNLDQK IILFIGSPFH
     VNEKQLINTG KQLKKNNISV DIISFGNIDK NRDKLMMLFE SVNNNDNCRF IECPEYENNL
     SKFVLNSFLN NNDFNIGNIQ DDDQLLNAMQ LSLEESQHMD KNLNTTNNIN TGSNHHTNNI
     TTNNNDLPTI EEIENMKDID NELKEALILS LREYTEKNKL ENKDTTSNNN NNNNESNNNN
     NESNNNNNES NNNNNESNNN NNESNNNNNE SNNNNNESNN NNNGNTCGNN NNNSLNFYKK
     DDNFALVNES YKNNFDKNDE NKLETSKEKK ENESYEKVFK IDKEENMEDT SKDIINEHIY
     KDIQHNDENN NVINQGEEKE QSASSLIQDP SYISNILGKI NPNVNVFDKK EGDSDKEKNK
     E
//

If you have problems or comments...

PBIL Back to PBIL home page