(data stored in ACNUC9543 zone)

SWISSPROT: Q8IAR5_PLAF7

ID   Q8IAR5_PLAF7            Unreviewed;       870 AA.
AC   Q8IAR5;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   08-MAY-2019, entry version 91.
DE   SubName: Full=Serine protease DegP {ECO:0000313|EMBL:CAD51295.1};
DE            EC=3.4.21.- {ECO:0000313|EMBL:CAD51295.1};
GN   ORFNames=PF3D7_0807700 {ECO:0000313|EMBL:CAD51295.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD51295.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA   Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S.,
RA   Chan M.S., Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S.,
RA   Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B.,
RA   Martin D.M., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A.,
RA   McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C.,
RA   Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W.,
RA   Fraser C.M., Barrell B.;
RT   "Genome sequence of the human malaria parasite Plasmodium
RT   falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C.,
RA   Chillingworth T., Christodoulou Z., Clark L., Clark R., Corton C.,
RA   Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J.,
RA   Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z.,
RA   Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P.,
RA   Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A.,
RA   Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N.,
RA   Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L.,
RA   Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E.,
RA   Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M.,
RA   Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K.,
RA   Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AL844507; CAD51295.1; -; Genomic_DNA.
DR   RefSeq; XP_001349446.1; XM_001349410.1.
DR   IntAct; Q8IAR5; 6.
DR   MINT; Q8IAR5; -.
DR   MEROPS; S01.B87; -.
DR   EnsemblProtists; CAD51295; CAD51295; PF3D7_0807700.
DR   GeneDB; PF3D7_0807700.1:pep; -.
DR   GeneID; 2655249; -.
DR   KEGG; pfa:PF3D7_0807700; -.
DR   EuPathDB; PlasmoDB:PF3D7_0807700; -.
DR   HOGENOM; HOG000283926; -.
DR   InParanoid; Q8IAR5; -.
DR   OMA; VAYSTRI; -.
DR   PhylomeDB; Q8IAR5; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0005829; C:cytosol; IDA:GeneDB.
DR   GO; GO:0044164; C:host cell cytosol; IDA:GeneDB.
DR   GO; GO:0020002; C:host cell plasma membrane; IDA:GeneDB.
DR   GO; GO:0020003; C:symbiont-containing vacuole; IDA:GeneDB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IDA:GeneDB.
DR   GO; GO:0006979; P:response to oxidative stress; IGI:GeneDB.
DR   GO; GO:0009266; P:response to temperature stimulus; IGI:GeneDB.
DR   InterPro; IPR041517; DEGP_PDZ.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR001940; Peptidase_S1C.
DR   Pfam; PF17815; PDZ_3; 1.
DR   PRINTS; PR00834; PROTEASES2C.
DR   SUPFAM; SSF50494; SSF50494; 1.
PE   4: Predicted;
DR   PRODOM; Q8IAR5.
DR   SWISS-2DPAGE; Q8IAR5.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001450};
KW   Hydrolase {ECO:0000313|EMBL:CAD51295.1};
KW   Protease {ECO:0000313|EMBL:CAD51295.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     29       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        30    870       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5004308142.
FT   DOMAIN      700    867       PDZ_3. {ECO:0000259|Pfam:PF17815}.
SQ   SEQUENCE   870 AA;  101494 MW;  50A25DD84EC772D6 CRC64;
     MDIIFCTPTY CKIMLMIIML ISLRTRCDTN NFLNCSVEKE EGEEEIISTN LKRINDDMNI
     LGRILNDERN IKITDIVEML QNEYDDKKKK KKKKKYIYRK KKSNNKINEI NSVQHFNVKE
     NILNEKKKNP LNDNFKNPKL RKHSPNNKKN KNKIGQIKFH IVGYDKKKIT KYLTPSMISS
     IQKRLMNKNK KTNVNVNMSN GRVLPFFPKE YFLHSSTHEK KDKMATKKNN KEESIINERL
     LENLENISLS RTIKDIRGEE GNERKVKEED NNIKEEGNSF KKYFKGVVKL YVDITEPNLE
     MIWQNYPPKS ITGSGFIIEG HLIITNAHNI SYSTRILIRK HGNSGKYEAK ILYVAHDVDI
     AILTTDDKTF FDDVYALHFG ALPSLKDEII TIGYPAGGDK LSVTEGIVSR IDVQYYKHSN
     YKFLLTQIDA PLNPGNSGGP ALVRGKVVGI CFQSYKVSNN ISYIIPSTII SHFLLDIHKN
     KDYTGYAFLG VKYEPLENPS LREALGLEEM ERKKIIKKNV GILITEVFEG HMSKQDDKYH
     DMDNKHHNVG DTHHNVGDTH HNVGDDHTDN LQGDTDYCTY ILNSNIITSD KKNIYSDKKK
     KKIYSDNNNN NNNFNYYYNM HGEDEQSCYG LKKNDIILRV DGKDINNDGS VILRDNETVG
     FQHLFNEKFI NDLCIIKIVR NKKIKSVMVK LYKVKYLLNQ HNWDKRNKYF IYGGIVFSIL
     TRSLYVYTQN PEINKLMLYN NFKKKSKDEI VVLKNILPTK ITTGYYYTDS IVLRVNNIKV
     KNLKHLIELI EMTKYTNRLM YLKNNKHTLQ SYINYYNTKI TSLNINTIIH ILILTTSGQK
     VPIVLNKRDV EKYNEEIKKI YSITRDRYVY
//

If you have problems or comments...

PBIL Back to PBIL home page