(data stored in ACNUC9543 zone)

SWISSPROT: Q8IAP0_PLAF7

ID   Q8IAP0_PLAF7            Unreviewed;       740 AA.
AC   Q8IAP0;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   08-MAY-2019, entry version 102.
DE   SubName: Full=Methionine aminopeptidase 1c, putative {ECO:0000313|EMBL:CAD51322.1};
DE            EC=3.4.11.18 {ECO:0000313|EMBL:CAD51322.1};
GN   ORFNames=PF3D7_0804400 {ECO:0000313|EMBL:CAD51322.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD51322.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA   Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S.,
RA   Chan M.S., Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S.,
RA   Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B.,
RA   Martin D.M., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A.,
RA   McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C.,
RA   Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W.,
RA   Fraser C.M., Barrell B.;
RT   "Genome sequence of the human malaria parasite Plasmodium
RT   falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C.,
RA   Chillingworth T., Christodoulou Z., Clark L., Clark R., Corton C.,
RA   Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J.,
RA   Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z.,
RA   Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P.,
RA   Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A.,
RA   Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N.,
RA   Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L.,
RA   Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E.,
RA   Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M.,
RA   Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K.,
RA   Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
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DR   EMBL; AL844507; CAD51322.1; -; Genomic_DNA.
DR   RefSeq; XP_001349473.1; XM_001349437.1.
DR   SMR; Q8IAP0; -.
DR   MEROPS; M24.A13; -.
DR   EnsemblProtists; CAD51322; CAD51322; PF3D7_0804400.
DR   GeneDB; PF3D7_0804400.1:pep; -.
DR   GeneID; 2655407; -.
DR   KEGG; pfa:PF3D7_0804400; -.
DR   EuPathDB; PlasmoDB:PF3D7_0804400; -.
DR   HOGENOM; HOG000284481; -.
DR   InParanoid; Q8IAP0; -.
DR   KO; K01265; -.
DR   OMA; NLVFTIE; -.
DR   PhylomeDB; Q8IAP0; -.
DR   BioCyc; PLASMO:MAL8P1.140-MONOMER; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008235; F:metalloexopeptidase activity; ISS:GeneDB.
DR   GO; GO:0006508; P:proteolysis; ISS:GeneDB.
DR   InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR   InterPro; IPR000994; Pept_M24.
DR   InterPro; IPR001714; Pept_M24_MAP.
DR   Pfam; PF00557; Peptidase_M24; 2.
DR   PRINTS; PR00599; MAPEPTIDASE.
DR   SUPFAM; SSF55920; SSF55920; 2.
PE   4: Predicted;
DR   PRODOM; Q8IAP0.
DR   SWISS-2DPAGE; Q8IAP0.
KW   Aminopeptidase {ECO:0000313|EMBL:CAD51322.1};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001450};
KW   Hydrolase {ECO:0000313|EMBL:CAD51322.1};
KW   Protease {ECO:0000313|EMBL:CAD51322.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    740       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5004310950.
FT   DOMAIN      273    388       Peptidase_M24. {ECO:0000259|Pfam:
FT                                PF00557}.
FT   DOMAIN      595    717       Peptidase_M24. {ECO:0000259|Pfam:
FT                                PF00557}.
FT   COILED      100    120       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   740 AA;  88179 MW;  44CEFD60A0E1EEF1 CRC64;
     MNISIFFFLF LYSGSICAIH LWRHSEWRGR NVLGGGKCRN NDNMLWLDLI KKNKKVNKKK
     NKNNNNNIIS SSCCCCCCCC IYNDKYCFLF VNKKIDNNYK RIKKKEKHNC KKRLKSLNNE
     GGFSNTYHND VKKNTLDYCE ERLPSYHRYI DNLKTRKIIH PSIRIRNLDK KFMKCKESYN
     KLYSHLKEND LFENFSYVGR QKKGILSPTY RLPKYIERPN YHKTGIPIYV PYDKEKKNNK
     TNSDHNNKYD HYNCNYDYNY YDNIKSDKDI QIIKENCKFA RELMDDVSYI ICEGITTNDI
     DIYILNKCIN NGFYPSPLNY HNFPKSSCIS INEILCHGIP DNNLLYLNDV VKIDISLFRN
     GYHADMCESF IVPKLSKNEK KKRKKFYDFI YLNNSFKTKY TKYILKYHYD LTKNKVVRRG
     KSFVTKKIKY AAPNSKEQND DLCNNDFDDN TTNVMNTSQK YCFNDIYEDK IPSHTNMHTN
     MHTNTQTHTN MHTHTHNRNN SYYPNNQMHN NEKNTFNMSN NVLQQEDDEL EYFHKYYDQK
     IIFNKENNEI YEDIQKFIYQ KSLNKTIGKK RFDFFDNTKM STNDIKNFMY QKNLDLIKTA
     YECTMAGISV CKDGTPFNKI AEAMDNYIKQ VNKKNNKTYS IVPHLCGHNI GKNFHEEPYI
     IHTLNNDQRK MCSNMVFTIE PIISESSTNF ILWPDNWTIS NTKYHFSAQF EHTILIQKNG
     AQILTDKRDI SPKYLWQQIN
//

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