(data stored in ACNUC9543 zone)

SWISSPROT: Q8IAN7_PLAF7

ID   Q8IAN7_PLAF7            Unreviewed;       452 AA.
AC   Q8IAN7;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   08-MAY-2019, entry version 113.
DE   RecName: Full=Tubulin gamma chain {ECO:0000256|RuleBase:RU000352};
GN   ORFNames=PF3D7_0803700 {ECO:0000313|EMBL:CAD51326.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD51326.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA   Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S.,
RA   Chan M.S., Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S.,
RA   Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B.,
RA   Martin D.M., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A.,
RA   McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C.,
RA   Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W.,
RA   Fraser C.M., Barrell B.;
RT   "Genome sequence of the human malaria parasite Plasmodium
RT   falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C.,
RA   Chillingworth T., Christodoulou Z., Clark L., Clark R., Corton C.,
RA   Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J.,
RA   Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z.,
RA   Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P.,
RA   Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A.,
RA   Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N.,
RA   Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L.,
RA   Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E.,
RA   Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M.,
RA   Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K.,
RA   Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
CC   -!- FUNCTION: Tubulin is the major constituent of microtubules. The
CC       gamma chain is found at microtubule organizing centers (MTOC) such
CC       as the spindle poles or the centrosome.
CC       {ECO:0000256|RuleBase:RU000352}.
CC   -!- SIMILARITY: Belongs to the tubulin family.
CC       {ECO:0000256|RuleBase:RU000352, ECO:0000256|SAAS:SAAS00576975}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AL844507; CAD51326.1; -; Genomic_DNA.
DR   RefSeq; XP_001349477.1; XM_001349441.1.
DR   SMR; Q8IAN7; -.
DR   IntAct; Q8IAN7; 1.
DR   PRIDE; Q8IAN7; -.
DR   EnsemblProtists; CAD51326; CAD51326; PF3D7_0803700.
DR   GeneDB; PF3D7_0803700.1:pep; -.
DR   GeneID; 2655324; -.
DR   KEGG; pfa:PF3D7_0803700; -.
DR   EuPathDB; PlasmoDB:PF3D7_0803700; -.
DR   HOGENOM; HOG000165714; -.
DR   InParanoid; Q8IAN7; -.
DR   KO; K10389; -.
DR   OMA; EGFMLMH; -.
DR   PhylomeDB; Q8IAN7; -.
DR   BioCyc; PLASMO:PF08_0125-MONOMER; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0005813; C:centrosome; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0000930; C:gamma-tubulin complex; IBA:GO_Central.
DR   GO; GO:0005874; C:microtubule; IBA:GO_Central.
DR   GO; GO:0005815; C:microtubule organizing center; ISS:GeneDB.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005819; C:spindle; IBA:GO_Central.
DR   GO; GO:0005525; F:GTP binding; IBA:GO_Central.
DR   GO; GO:0003924; F:GTPase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; ISS:GeneDB.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IEA:InterPro.
DR   GO; GO:0000212; P:meiotic spindle organization; IBA:GO_Central.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; ISS:GeneDB.
DR   GO; GO:0007020; P:microtubule nucleation; IBA:GO_Central.
DR   GO; GO:0007017; P:microtubule-based process; IBA:GO_Central.
DR   GO; GO:0000278; P:mitotic cell cycle; IBA:GO_Central.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IBA:GO_Central.
DR   GO; GO:0007052; P:mitotic spindle organization; IBA:GO_Central.
DR   CDD; cd02188; gamma_tubulin; 1.
DR   Gene3D; 1.10.287.600; -; 1.
DR   Gene3D; 3.30.1330.20; -; 1.
DR   Gene3D; 3.40.50.1440; -; 1.
DR   InterPro; IPR002454; Gamma_tubulin.
DR   InterPro; IPR008280; Tub_FtsZ_C.
DR   InterPro; IPR000217; Tubulin.
DR   InterPro; IPR018316; Tubulin/FtsZ_2-layer-sand-dom.
DR   InterPro; IPR037103; Tubulin/FtsZ_C_sf.
DR   InterPro; IPR036525; Tubulin/FtsZ_GTPase_sf.
DR   InterPro; IPR023123; Tubulin_C.
DR   InterPro; IPR017975; Tubulin_CS.
DR   InterPro; IPR003008; Tubulin_FtsZ_GTPase.
DR   PANTHER; PTHR11588; PTHR11588; 1.
DR   Pfam; PF00091; Tubulin; 1.
DR   Pfam; PF03953; Tubulin_C; 1.
DR   PRINTS; PR01164; GAMMATUBULIN.
DR   PRINTS; PR01161; TUBULIN.
DR   SMART; SM00864; Tubulin; 1.
DR   SMART; SM00865; Tubulin_C; 1.
DR   SUPFAM; SSF52490; SSF52490; 1.
DR   SUPFAM; SSF55307; SSF55307; 1.
DR   PROSITE; PS00227; TUBULIN; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q8IAN7.
DR   SWISS-2DPAGE; Q8IAN7.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001450};
KW   GTP-binding {ECO:0000256|RuleBase:RU000352,
KW   ECO:0000256|SAAS:SAAS00977278};
KW   Microtubule {ECO:0000256|RuleBase:RU000352,
KW   ECO:0000256|SAAS:SAAS00576796};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000352,
KW   ECO:0000256|SAAS:SAAS00977287};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT   DOMAIN       48    248       Tubulin. {ECO:0000259|SMART:SM00864}.
FT   DOMAIN      250    391       Tubulin_C. {ECO:0000259|SMART:SM00865}.
FT   COILED      424    444       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   452 AA;  51637 MW;  7CA2845F6456136D CRC64;
     MPREIITLQC GQCGNQIGVE FWKQLCNEHN IDQEGILKNN NFLNEDRKDI FFYQADDEHF
     IPRALLFDLE PRVINSIQTS EYRNLYNPEN MFISKEGGGA GNNWGCGYSQ GHKVEEEIID
     MIDREVDNSD NLEGFILSHS IAGGTGSGMG SYLLELLNDN YSKKMIQTFS VFPLLTNESS
     DVVVQPYNSI LTLKRLILST DSVVVIDNTS LNRIFVERLK LNNPTFQQTN TIISNVMSAS
     TTTLRYPGSM NNDMISLISS LIINPKCHFL ITSYTPITID KHISNVQKTT VLDVMKRLLH
     TKNIMVSAPV RRGMYISILN IIRGETDPTQ VHKGLQRIRD RKLVNFIKWN PASIQVTLAK
     QSPHVVSQHK VCGLMMANHT SISTLFERCV TQFDRLYKRR AFLENYKKES MFSSADGQGN
     FEEMESSKEI TQNLIDEYKS AERDDYFTNT YI
//

If you have problems or comments...

PBIL Back to PBIL home page