(data stored in SCRATCH zone)

SWISSPROT: Q8IAN4_PLAF7

ID   Q8IAN4_PLAF7            Unreviewed;      1239 AA.
AC   Q8IAN4;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   11-DEC-2019, entry version 104.
DE   SubName: Full=DNA repair and recombination protein RAD54, putative {ECO:0000313|EMBL:CAD51329.1};
DE            EC=3.6.4.12 {ECO:0000313|EMBL:CAD51329.1};
GN   ORFNames=PF3D7_0803400 {ECO:0000313|EMBL:CAD51329.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD51329.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA   Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA   Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA   Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA   Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA   Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA   Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA   Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA   Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA   Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA   Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
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DR   EMBL; AL844507; CAD51329.1; -; Genomic_DNA.
DR   RefSeq; XP_001349480.1; XM_001349444.1.
DR   IntAct; Q8IAN4; 2.
DR   PRIDE; Q8IAN4; -.
DR   EnsemblProtists; CAD51329; CAD51329; PF3D7_0803400.
DR   GeneDB; PF3D7_0803400.1:pep; -.
DR   GeneID; 2655325; -.
DR   KEGG; pfa:PF3D7_0803400; -.
DR   EuPathDB; PlasmoDB:PF3D7_0803400; -.
DR   HOGENOM; HOG000204521; -.
DR   InParanoid; Q8IAN4; -.
DR   KO; K10875; -.
DR   OMA; PFAVTNI; -.
DR   PhylomeDB; Q8IAN4; -.
DR   BioCyc; PLASMO:PF08_0126-MONOMER; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003684; F:damaged DNA binding; ISS:GeneDB.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:UniProtKB-EC.
DR   GO; GO:0015616; F:DNA translocase activity; IBA:GO_Central.
DR   GO; GO:0006310; P:DNA recombination; ISS:GeneDB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; ISS:GeneDB.
DR   GO; GO:0045003; P:double-strand break repair via synthesis-dependent strand annealing; IBA:GO_Central.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IBA:GO_Central.
DR   Gene3D; 3.40.50.10810; -; 1.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038718; SNF2-like_sf.
DR   InterPro; IPR000330; SNF2_N.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00176; SNF2_N; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
DR   PRODOM; Q8IAN4.
DR   SWISS-2DPAGE; Q8IAN4.
KW   Hydrolase {ECO:0000313|EMBL:CAD51329.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT   DOMAIN          150..321
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          614..770
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          495..532
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          816..851
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          935..1104
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1116..1239
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..22
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        821..846
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        955..976
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        977..1033
FT                   /note="Acidic"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1034..1104
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1116..1155
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1156..1221
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1223..1239
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1239 AA;  143045 MW;  C51C493A0A8E66AA CRC64;
     MRKYNGNVKR SRDDEYEENE NVNGERTSIT LVRATLLPIL SIGKNEKTTL FHPFKNPLPG
     FVSDKTLYLK KTLGVKVRRT GWINLMKNSI PRRSDETEEQ EKIEEVIKKH EPLILYKDEN
     DKIEVDPILA QYLREHQREG VQFVFECLMN IKDDKISGCI LADDMGLGKT LQSITVLYTL
     LKQGFHKKCA VRRCLILCPA SLINNWNDEI SKWIPNRCNV TCVNDNAKEK IVSKLEGFKY
     DIQSTVLICS YECFRINNEF LDKSSIDMII CDEAHRLKND KTKTYTSIYN LTAKKRLLLS
     GTPIQNDLGE FYALISLCNP DLFDDINLFR KKFANPILIG RDKDATEKEQ EIASERLTEL
     SNITNKFILR RTNNLLSKVL PVKYLINIFI KLNPIQEALY VLFLKDKKIL KNDNTNNKVN
     VLINIKKLEK ICNHPLLLNV NDIKEIGQVT LWKLIEDVIF EMQTNMKICN RGNKRDNKND
     SKSGCVLKVD KSMSSISNNN MKNGNDMNNT NNNTNNNTNN NTNNNTNNNI NSNINNNINN
     NINSNINNNI NSNMNNNTNL RCGSRGNQND ASGYVGNKRK PIELDYNKPV KRIIEECKRD
     IYRSYYNFSC KFLLLHFLLK NIKQNTNDKV VIVSNYTQTL DYMEILCKEN MYKFVRLDGG
     INIKKRHKVI NDFTHSADIF IFLLSSKSGG CGINLISSNR LILLDPDWNP ANDKQALARV
     WREGQKKICY IYRLFCTGTI DEKVYQRQIS KDGLSNMIVT TTNLSKDQMS DENVKKLFNY
     KMNTVSETHD NIECNRCNLN GVSPNIHKVA HVDSINKNKS KGKNDNNNNN NNNNSNSNGN
     GNNYKSDDDK NYIDGEHFAE QLEDFEEDDV NTWAHHQNID TVPDNILIKA VKDAEEYKKN
     DMNSMPLLQK LTHDFVTFTM SCKIEYRDDL IKQKSEQAKM REKGASQTNG KSMKEMKLES
     QDGKKGKGHK NGKREEDEDE DEFDGDEEDN DEEDEFDDDD DEEEEENDDD NDEEDEFVDE
     EEDDRDESNE SDDDVQEVGV HSGLDKIKNK KMENIIESDR DEPSDACRKK LNELVQYQRE
     RKKREEEFLN KKREPLSDDD KEKVVCLKEE KSNIKGNIKS NTNNNTNNNT NNITNNITNN
     NINGSASTST RHDNNIENNN MKKEEEANYG NNSHNKNKNE EKIKNGKDEP SKRITRNMSH
     RSLVELLSQD EDSKESLTMS EDIEEMSAEN VSTDSSYFI
//

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