(data stored in ACNUC1104 zone)

SWISSPROT: Q7WAK4_BORPA

ID   Q7WAK4_BORPA            Unreviewed;       320 AA.
AC   Q7WAK4;
DT   01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2003, sequence version 1.
DT   08-MAY-2019, entry version 96.
DE   SubName: Full=Probable 3-hydroxybutyryl-CoA dehydrogenase {ECO:0000313|EMBL:CAE36674.1};
DE            EC=1.1.1.157 {ECO:0000313|EMBL:CAE36674.1};
GN   OrderedLocusNames=BPP1372 {ECO:0000313|EMBL:CAE36674.1};
OS   Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=257311 {ECO:0000313|Proteomes:UP000001421};
RN   [1] {ECO:0000313|Proteomes:UP000001421}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12822 / ATCC BAA-587 / NCTC 13253
RC   {ECO:0000313|Proteomes:UP000001421};
RX   PubMed=12910271; DOI=10.1038/ng1227;
RA   Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.,
RA   Harris D.E., Holden M.T., Churcher C.M., Bentley S.D., Mungall K.L.,
RA   Cerdeno-Tarraga A.M., Temple L., James K., Harris B., Quail M.A.,
RA   Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I.,
RA   Chillingworth T., Collins M., Cronin A., Davis P., Doggett J.,
RA   Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K.,
RA   Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C.,
RA   Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K.,
RA   Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K.,
RA   Unwin L., Whitehead S., Barrell B.G., Maskell D.J.;
RT   "Comparative analysis of the genome sequences of Bordetella pertussis,
RT   Bordetella parapertussis and Bordetella bronchiseptica.";
RL   Nat. Genet. 35:32-40(2003).
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DR   EMBL; BX640427; CAE36674.1; -; Genomic_DNA.
DR   RefSeq; WP_003812148.1; NC_002928.3.
DR   EnsemblBacteria; CAE36674; CAE36674; BPP1372.
DR   KEGG; bpa:BPP1372; -.
DR   HOGENOM; HOG000141498; -.
DR   KO; K00074; -.
DR   OMA; MAHPMGP; -.
DR   BioCyc; BPAR257311:G1GSY-1411-MONOMER; -.
DR   Proteomes; UP000001421; Chromosome.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0008691; F:3-hydroxybutyryl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.1040.10; -; 1.
DR   InterPro; IPR022694; 3-OHacyl-CoA_DH.
DR   InterPro; IPR006180; 3-OHacyl-CoA_DH_CS.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   PIRSF; PIRSF000105; HCDH; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00067; 3HCDH; 1.
PE   4: Predicted;
DR   PRODOM; Q7WAK4.
DR   SWISS-2DPAGE; Q7WAK4.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001421};
KW   Oxidoreductase {ECO:0000256|SAAS:SAAS00324627,
KW   ECO:0000313|EMBL:CAE36674.1}.
FT   DOMAIN       17    187       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      190    288       3HCDH. {ECO:0000259|Pfam:PF00725}.
FT   SITE        143    143       Important for catalytic activity.
FT                                {ECO:0000256|PIRSR:PIRSR000105-1}.
SQ   SEQUENCE   320 AA;  33699 MW;  8BEAD8A015AEB770 CRC64;
     MSSPDSALGR PGASHAVVIG GGTMGADVAV VLARALCRTT VVEPDAARAA ALPRRAADNL
     AQAGRAEGAA HIAVVPGLDA VEWDSVGLVI ECVPERLDIK QALFAELARR APAHAILASN
     SSSFPISAIG AGLPTRERML GLHFFMPAHL VPLVEVVLCE ASDPACADVL IAFMRRCGMV
     PVRVAQDLPG FLANRLQHAL SREAFDLIDR GIASPEDVDA AVRFGFGFRF LAAGPVMQRD
     HAGIDVHAAA GATMYPTFCN ADTPARCLTE RAADGRHGMK AGTGFYAWTP ETIAAERARY
     DRLLRAGLDL LGAELPEIQP
//

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