(data stored in ACNUC1104 zone)

SWISSPROT: UBIC_BORPA

ID   UBIC_BORPA              Reviewed;         190 AA.
AC   Q7WAC9;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   08-MAY-2019, entry version 73.
DE   RecName: Full=Probable chorismate pyruvate-lyase {ECO:0000255|HAMAP-Rule:MF_01632};
DE            Short=CL {ECO:0000255|HAMAP-Rule:MF_01632};
DE            Short=CPL {ECO:0000255|HAMAP-Rule:MF_01632};
DE            EC=4.1.3.40 {ECO:0000255|HAMAP-Rule:MF_01632};
GN   Name=ubiC {ECO:0000255|HAMAP-Rule:MF_01632};
GN   OrderedLocusNames=BPP1450;
OS   Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=257311;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12822 / ATCC BAA-587 / NCTC 13253;
RX   PubMed=12910271; DOI=10.1038/ng1227;
RA   Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R.,
RA   Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L.,
RA   Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A.,
RA   Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I.,
RA   Chillingworth T., Collins M., Cronin A., Davis P., Doggett J.,
RA   Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K.,
RA   Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C.,
RA   Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K.,
RA   Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K.,
RA   Unwin L., Whitehead S., Barrell B.G., Maskell D.J.;
RT   "Comparative analysis of the genome sequences of Bordetella pertussis,
RT   Bordetella parapertussis and Bordetella bronchiseptica.";
RL   Nat. Genet. 35:32-40(2003).
CC   -!- FUNCTION: Removes the pyruvyl group from chorismate, with
CC       concomitant aromatization of the ring, to provide 4-
CC       hydroxybenzoate (4HB) for the ubiquinone pathway.
CC       {ECO:0000255|HAMAP-Rule:MF_01632}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=chorismate = 4-hydroxybenzoate + pyruvate;
CC         Xref=Rhea:RHEA:16505, ChEBI:CHEBI:15361, ChEBI:CHEBI:17879,
CC         ChEBI:CHEBI:29748; EC=4.1.3.40; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_01632};
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_01632}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01632}.
CC   -!- SIMILARITY: Belongs to the UbiC family. {ECO:0000255|HAMAP-
CC       Rule:MF_01632}.
DR   EMBL; BX640427; CAE36752.1; -; Genomic_DNA.
DR   RefSeq; WP_010926548.1; NC_002928.3.
DR   EnsemblBacteria; CAE36752; CAE36752; BPP1450.
DR   KEGG; bpa:BPP1450; -.
DR   HOGENOM; HOG000137785; -.
DR   KO; K03181; -.
DR   OMA; ELWGRRS; -.
DR   BioCyc; BPAR257311:G1GSY-1490-MONOMER; -.
DR   UniPathway; UPA00232; -.
DR   Proteomes; UP000001421; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008813; F:chorismate lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042866; P:pyruvate biosynthetic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.1410.10; -; 1.
DR   HAMAP; MF_01632; UbiC; 1.
DR   InterPro; IPR007440; Chorismate--pyruvate_lyase.
DR   InterPro; IPR028978; Chorismate_lyase_/UTRA_dom_sf.
DR   PANTHER; PTHR38683; PTHR38683; 1.
DR   Pfam; PF04345; Chor_lyase; 1.
DR   SUPFAM; SSF64288; SSF64288; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q7WAC9.
DR   SWISS-2DPAGE; Q7WAC9.
KW   Complete proteome; Cytoplasm; Lyase; Pyruvate;
KW   Ubiquinone biosynthesis.
FT   CHAIN         1    190       Probable chorismate pyruvate-lyase.
FT                                /FTId=PRO_0000255901.
FT   BINDING      74     74       Substrate. {ECO:0000255|HAMAP-
FT                                Rule:MF_01632}.
FT   BINDING     112    112       Substrate; via amide nitrogen.
FT                                {ECO:0000255|HAMAP-Rule:MF_01632}.
FT   BINDING     173    173       Substrate. {ECO:0000255|HAMAP-
FT                                Rule:MF_01632}.
SQ   SEQUENCE   190 AA;  20877 MW;  9ADE578C94FC2234 CRC64;
     MTTPIPLARG WLPAAPSTLD PLRKYWLFRP GALTAGLRQL GHVRLRVLAE YPTGAPRDEA
     DGMRIAAQSP VWVREVLMSI DGVDSVVARS LTPLRASHGV WQGMRRLLTR PLADMLYHDP
     GIHRSVFVCR RLAAGVPFHA TAIARAPAGG PEPALWARRS AFWRAGQPLL VAECFLPAFW
     SLARAPVAPR
//

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