(data stored in ACNUC1104 zone)

SWISSPROT: Q7WA32_BORPA

ID   Q7WA32_BORPA            Unreviewed;       348 AA.
AC   Q7WA32;
DT   01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2003, sequence version 1.
DT   08-MAY-2019, entry version 70.
DE   RecName: Full=Endolytic murein transglycosylase {ECO:0000256|HAMAP-Rule:MF_02065};
DE            EC=4.2.2.- {ECO:0000256|HAMAP-Rule:MF_02065};
DE   AltName: Full=Peptidoglycan polymerization terminase {ECO:0000256|HAMAP-Rule:MF_02065};
GN   Name=mltG {ECO:0000256|HAMAP-Rule:MF_02065};
GN   OrderedLocusNames=BPP1558 {ECO:0000313|EMBL:CAE36860.1};
OS   Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=257311 {ECO:0000313|Proteomes:UP000001421};
RN   [1] {ECO:0000313|Proteomes:UP000001421}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12822 / ATCC BAA-587 / NCTC 13253
RC   {ECO:0000313|Proteomes:UP000001421};
RX   PubMed=12910271; DOI=10.1038/ng1227;
RA   Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.,
RA   Harris D.E., Holden M.T., Churcher C.M., Bentley S.D., Mungall K.L.,
RA   Cerdeno-Tarraga A.M., Temple L., James K., Harris B., Quail M.A.,
RA   Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I.,
RA   Chillingworth T., Collins M., Cronin A., Davis P., Doggett J.,
RA   Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K.,
RA   Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C.,
RA   Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K.,
RA   Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K.,
RA   Unwin L., Whitehead S., Barrell B.G., Maskell D.J.;
RT   "Comparative analysis of the genome sequences of Bordetella pertussis,
RT   Bordetella parapertussis and Bordetella bronchiseptica.";
RL   Nat. Genet. 35:32-40(2003).
CC   -!- FUNCTION: Functions as a peptidoglycan terminase that cleaves
CC       nascent peptidoglycan strands endolytically to terminate their
CC       elongation. {ECO:0000256|HAMAP-Rule:MF_02065}.
CC   -!- SIMILARITY: Belongs to the transglycosylase MltG family.
CC       {ECO:0000256|HAMAP-Rule:MF_02065}.
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DR   EMBL; BX640427; CAE36860.1; -; Genomic_DNA.
DR   EnsemblBacteria; CAE36860; CAE36860; BPP1558.
DR   KEGG; bpa:BPP1558; -.
DR   HOGENOM; HOG000050562; -.
DR   KO; K07082; -.
DR   OMA; LVEGWTF; -.
DR   BioCyc; BPAR257311:G1GSY-1598-MONOMER; -.
DR   Proteomes; UP000001421; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008932; F:lytic endotransglycosylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR   GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-UniRule.
DR   CDD; cd08010; yceG_like; 1.
DR   HAMAP; MF_02065; MltG; 1.
DR   InterPro; IPR003770; YceG.
DR   PANTHER; PTHR30518; PTHR30518; 1.
DR   Pfam; PF02618; YceG; 1.
DR   TIGRFAMs; TIGR00247; TIGR00247; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q7WA32.
DR   SWISS-2DPAGE; Q7WA32.
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_02065};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_02065};
KW   Cell wall biogenesis/degradation {ECO:0000256|HAMAP-Rule:MF_02065};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001421};
KW   Lyase {ECO:0000256|HAMAP-Rule:MF_02065};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_02065};
KW   Transmembrane {ECO:0000256|HAMAP-Rule:MF_02065};
KW   Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_02065}.
FT   SITE        223    223       Important for catalytic activity.
FT                                {ECO:0000256|HAMAP-Rule:MF_02065}.
SQ   SEQUENCE   348 AA;  39126 MW;  A853CFB0FDD32C23 CRC64;
     MRTLMRKRIR FYFLLLVLVA LLGAALAAGG AWTWMHRPVA LKSDRIDFVV DPGSTPRAIA
     RTLNQAGVAV WEPGFVWMAR LSELDKQIKA GGYQAIDGDS PWQLLQRLAR GDMSQRQITF
     LEGWMFRQMR QALREHPDVK QTLGETSDEA LMERLGSTVT HPEGMFFPDT YVFTPGSTDF
     DILRRAYQEG QRILESTWAK RQDGLPVGTP YEALILASIV EKETGHGPER ARVAGVFANR
     LRIGMLLQTD PTVIYGMGEA YQGRIRKRDL QTDTPWNTYT RPGLPPTPIA APGRAALLAA
     VQPERHKYLF FVSRGNGTSE FSVNLNDHNR NVSRYILGQG QPQQGSQQ
//

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