(data stored in ACNUC9435 zone)

SWISSPROT: YOPD_YERPS

ID   YOPD_YERPS              Reviewed;         306 AA.
AC   Q06131; Q663L2;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 2.
DT   11-DEC-2019, entry version 95.
DE   RecName: Full=Protein YopD;
GN   Name=yopD; OrderedLocusNames=pYV0054;
OS   Yersinia pseudotuberculosis serotype I (strain IP32953).
OG   Plasmid pIB1, and Plasmid pYV.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=273123;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PARTIAL PROTEIN SEQUENCE.
RC   STRAIN=YPIII / Serotype O:3; PLASMID=pIB1;
RX   PubMed=8418066;
RA   Haakansson S., Bergman T., Vanooteghem J.-C., Cornelis G., Wolf-Watz H.;
RT   "YopB and YopD constitute a novel class of Yersinia Yop proteins.";
RL   Infect. Immun. 61:71-80(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IP32953; PLASMID=pYV;
RX   PubMed=15358858; DOI=10.1073/pnas.0404012101;
RA   Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O.,
RA   Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L.,
RA   Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C.,
RA   Simonet M., Chenal-Francisque V., Souza B., Dacheux D., Elliott J.M.,
RA   Derbise A., Hauser L.J., Garcia E.;
RT   "Insights into the evolution of Yersinia pestis through whole-genome
RT   comparison with Yersinia pseudotuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004).
CC   -!- FUNCTION: Interacts with the target membrane to form channel structures
CC       involved either in translocation of YopE into the cytoplasmic space of
CC       the target cell or in the cytotoxic effect of the YopE protein.
DR   EMBL; L06215; AAA72322.1; -; Genomic_DNA.
DR   EMBL; BX936399; CAF25397.1; -; Genomic_DNA.
DR   RefSeq; WP_002212987.1; NZ_CP009711.1.
DR   PDB; 1KDL; NMR; -; A=278-300.
DR   PDB; 1OOS; Model; -; B=278-300.
DR   PDBsum; 1KDL; -.
DR   PDBsum; 1OOS; -.
DR   SMR; Q06131; -.
DR   TCDB; 1.C.36.2.1; the bacterial type iii-target cell pore (iiitcp) family.
DR   PRIDE; Q06131; -.
DR   EnsemblBacteria; CAF25397; CAF25397; pYV0054.
DR   KEGG; yps:pYV0054; -.
DR   HOGENOM; HOG000219599; -.
DR   KO; K23476; -.
DR   OMA; DEMRHGA; -.
DR   EvolutionaryTrace; Q06131; -.
DR   Proteomes; UP000001011; Plasmid pYV.
DR   InterPro; IPR008898; YopD-like.
DR   Pfam; PF05844; YopD; 1.
PE   1: Evidence at protein level;
DR   PRODOM; Q06131.
DR   SWISS-2DPAGE; Q06131.
KW   3D-structure; Direct protein sequencing; Plasmid.
FT   CHAIN           1..306
FT                   /note="Protein YopD"
FT                   /id="PRO_0000066364"
FT   CONFLICT        183
FT                   /note="S -> G (in Ref. 1; AAA72322)"
FT                   /evidence="ECO:0000305"
FT   HELIX           280..291
FT                   /evidence="ECO:0000244|PDB:1KDL"
FT   TURN            292..295
FT                   /evidence="ECO:0000244|PDB:1KDL"
SQ   SEQUENCE   306 AA;  33387 MW;  4C0F0E9BCA215DA2 CRC64;
     MTINIKTDSP IITTGSQLDA ITTETVKQSG EIKKTEDTRH EAQAIKSSEA SLSRSQVPEL
     IKPSQGINVA LLSKSQGDLN GTLSILLLLL ELARKAREMG LQQRDIENKA TITAQKEQVA
     EMVSGAKLMI AMAVVSGIMA ATSTVASAFS IAKEVKIVKQ EQILNSNIAG REQLIDTKMQ
     QMSNIGDKAV SREDIGRIWK PEQVADQNKL ALLDKEFRMT DSKANAFNAA TQPLGQMANS
     AIQVHQGYSQ AEVKEKEVNA SIAANEKQKA EEAMNYNDNF MKDVLRLIEQ YVSSHTHAMK
     AAFGVV
//

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