(data stored in ACNUC9435 zone)

SWISSPROT: LCRH_YERPS

ID   LCRH_YERPS              Reviewed;         168 AA.
AC   P23995; Q663L0;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   11-DEC-2019, entry version 107.
DE   RecName: Full=Low calcium response locus protein H;
GN   Name=lcrH; OrderedLocusNames=pYV0056;
OS   Yersinia pseudotuberculosis serotype I (strain IP32953).
OG   Plasmid pIB1, and Plasmid pYV.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=273123;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=YPIII / Serotype O:3; PLASMID=pIB1;
RX   PubMed=1705541; DOI=10.1128/jb.173.5.1607-1616.1991;
RA   Bergman T., Haakansson S., Forsberg A., Norlander L., Macellaro A.,
RA   Baeckman A., Boelin I., Wolf-Watz H.;
RT   "Analysis of the V antigen lcrGVH-yopBD operon of Yersinia
RT   pseudotuberculosis: evidence for a regulatory role of LcrH and LcrV.";
RL   J. Bacteriol. 173:1607-1616(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IP32953; PLASMID=pYV;
RX   PubMed=15358858; DOI=10.1073/pnas.0404012101;
RA   Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O.,
RA   Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L.,
RA   Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C.,
RA   Simonet M., Chenal-Francisque V., Souza B., Dacheux D., Elliott J.M.,
RA   Derbise A., Hauser L.J., Garcia E.;
RT   "Insights into the evolution of Yersinia pestis through whole-genome
RT   comparison with Yersinia pseudotuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004).
CC   -!- FUNCTION: Mediates the negative regulation of the lcrGVH operon by ATP
CC       or calcium. Acts as a modulator of the yop operon expression.
CC   -!- SIMILARITY: Belongs to the LcrH/SycD chaperone family. {ECO:0000305}.
DR   EMBL; M57893; AAA27646.1; -; Genomic_DNA.
DR   EMBL; BX936399; CAF25399.1; -; Genomic_DNA.
DR   PIR; C37314; C37314.
DR   RefSeq; WP_011117633.1; NZ_CP009711.1.
DR   PDB; 1OOL; Model; -; A=32-165.
DR   PDB; 1OOS; Model; -; A=1-168.
DR   PDBsum; 1OOL; -.
DR   PDBsum; 1OOS; -.
DR   SMR; P23995; -.
DR   EnsemblBacteria; CAF25399; CAF25399; pYV0056.
DR   GeneID; 39573343; -.
DR   KEGG; ypo:BZ17_4277; -.
DR   KEGG; yps:pYV0056; -.
DR   PATRIC; fig|273123.14.peg.4513; -.
DR   HOGENOM; HOG000219601; -.
DR   OMA; NEPRFPF; -.
DR   Proteomes; UP000001011; Plasmid pYV.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR005415; T3SS_Ca_resp_chp_LcrH/SycD.
DR   InterPro; IPR016379; T3SS_Ca_resp_chp_LcrH/SycD_sub.
DR   InterPro; IPR011716; TPR-3.
DR   InterPro; IPR013026; TPR-contain_dom.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF07720; TPR_3; 1.
DR   PIRSF; PIRSF003165; Chaperone_SicA; 1.
DR   PRINTS; PR01595; SYCDCHAPRONE.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   TIGRFAMs; TIGR02552; LcrH_SycD; 1.
DR   PROSITE; PS50293; TPR_REGION; 1.
PE   3: Inferred from homology;
DR   PRODOM; P23995.
DR   SWISS-2DPAGE; P23995.
KW   3D-structure; Chaperone; Plasmid.
FT   CHAIN           1..168
FT                   /note="Low calcium response locus protein H"
FT                   /id="PRO_0000206486"
SQ   SEQUENCE   168 AA;  19011 MW;  2CE06AF240EB0424 CRC64;
     MQQETTDTQE YQLAMESFLK GGGTIAMLNE ISSDTLEQLY SLAFNQYQSG KYEDAHKVFQ
     ALCVLDHYDS RFFLGLGACR QAMGQYDLAI HSYSYGAIMD IKEPRFPFHA AECLLQKGEL
     AEAESGLFLA QELIADKPEF KELSTRVSSM LEAIKLKKEM EHECVDNP
//

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