(data stored in ACNUC9435 zone)

SWISSPROT: YSCJ_YERPS

ID   YSCJ_YERPS              Reviewed;         244 AA.
AC   P69973; Q00926; Q663I0;
DT   04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   11-DEC-2019, entry version 75.
DE   RecName: Full=Yop proteins translocation lipoprotein J;
DE   AltName: Full=Lipoprotein YlpB;
DE   AltName: Full=Low calcium response locus protein KA;
DE   Flags: Precursor;
GN   Name=yscJ; Synonyms=lcrKA, ylpB; OrderedLocusNames=pYV0086;
OS   Yersinia pseudotuberculosis serotype I (strain IP32953).
OG   Plasmid pIB1, and Plasmid pYV.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=273123;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=YPIII / Serotype O:3; PLASMID=pIB1;
RX   PubMed=1577700; DOI=10.1128/jb.174.10.3355-3363.1992;
RA   Rimpilaeinen M., Forsberg A., Wolf-Watz H.;
RT   "A novel protein, LcrQ, involved in the low-calcium response of Yersinia
RT   pseudotuberculosis shows extensive homology to YopH.";
RL   J. Bacteriol. 174:3355-3363(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IP32953; PLASMID=pYV;
RX   PubMed=15358858; DOI=10.1073/pnas.0404012101;
RA   Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O.,
RA   Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L.,
RA   Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C.,
RA   Simonet M., Chenal-Francisque V., Souza B., Dacheux D., Elliott J.M.,
RA   Derbise A., Hauser L.J., Garcia E.;
RT   "Insights into the evolution of Yersinia pestis through whole-genome
RT   comparison with Yersinia pseudotuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004).
CC   -!- FUNCTION: Required for the export process of the Yop proteins.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Lipid-anchor.
CC   -!- INDUCTION: At 37 degrees Celsius in the absence of calcium.
CC   -!- SIMILARITY: Belongs to the YscJ lipoprotein family. {ECO:0000305}.
DR   EMBL; M83986; AAA27651.1; -; Genomic_DNA.
DR   EMBL; BX936399; CAF25429.1; -; Genomic_DNA.
DR   RefSeq; WP_002212912.1; NZ_CP009711.1.
DR   SMR; P69973; -.
DR   IntAct; P69973; 1.
DR   EnsemblBacteria; CAF25429; CAF25429; pYV0086.
DR   GeneID; 39573295; -.
DR   KEGG; yps:pYV0086; -.
DR   HOGENOM; HOG000214127; -.
DR   KO; K03222; -.
DR   OMA; YVYALSE; -.
DR   Proteomes; UP000001011; Plasmid pYV.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   InterPro; IPR003282; T3SS_HrcJ/YscJ.
DR   InterPro; IPR006182; YscJ_FliF.
DR   Pfam; PF01514; YscJ_FliF; 1.
DR   PRINTS; PR01338; TYPE3OMKPROT.
DR   TIGRFAMs; TIGR02544; III_secr_YscJ; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; P69973.
DR   SWISS-2DPAGE; P69973.
KW   Cell outer membrane; Lipoprotein; Membrane; Palmitate; Plasmid;
KW   Protein transport; Signal; Transmembrane; Transmembrane helix; Transport;
KW   Virulence.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000305"
FT   CHAIN           19..244
FT                   /note="Yop proteins translocation lipoprotein J"
FT                   /id="PRO_0000018232"
FT   TRANSMEM        218..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   LIPID           19
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           19
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   244 AA;  27042 MW;  8DDA9E712938D8BC CRC64;
     MKVKTSLSTL ILILFLTGCK VDLYTGISQK EGNEMLALLR QEGLSADKEP DKDGKIKLLV
     EESDVAQAID ILKRKGYPHE SFSTLQDVFP KDGLISSPIE ELARLNYAKA QEISRTLSEI
     DGVLVARVHV VLPEEQNNKG KKGVAASASV FIKHAADIQF DTYIPQIKQL VNNSIEGLAY
     DRISVILVPS VDVRQSSHLP RNTSILSIQV SEESKGHLIG LLSLLILLLP VTNLAQYFWL
     QRKK
//

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