(data stored in ACNUC8465 zone)

SWISSPROT: SHE9_CANGA

ID   SHE9_CANGA              Reviewed;         405 AA.
AC   Q6FK33;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   30-AUG-2017, entry version 59.
DE   RecName: Full=Sensitive to high expression protein 9 homolog, mitochondrial;
DE   Flags: Precursor;
GN   Name=SHE9; OrderedLocusNames=CAGL0M01518g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 /
OS   NRRL Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S.,
RA   Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E.,
RA   Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V.,
RA   Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C.,
RA   Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A.,
RA   Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A.,
RA   Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R.,
RA   Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H.,
RA   Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O.,
RA   Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A.,
RA   Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B.,
RA   Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A.,
RA   Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA   Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for the maintenance of the structure of the
CC       mitochondrial inner membrane. Involved in mitochondrial
CC       morphology. Causes growth arrest when highly overexpressed (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homooligomer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SHE9 family. {ECO:0000305}.
DR   EMBL; CR380959; CAG62387.1; -; Genomic_DNA.
DR   RefSeq; XP_449411.1; XM_449411.1.
DR   SMR; Q6FK33; -.
DR   EnsemblFungi; CAG62387; CAG62387; CAGL0M01518g.
DR   KEGG; cgr:CAGL0M01518g; -.
DR   CGD; CAL0136279; SHE9.
DR   EuPathDB; FungiDB:CAGL0M01518g; -.
DR   eggNOG; ENOG410IEND; Eukaryota.
DR   eggNOG; ENOG4111HP4; LUCA.
DR   InParanoid; Q6FK33; -.
DR   KO; K17983; -.
DR   OrthoDB; EOG092C4PM4; -.
DR   Proteomes; UP000002428; Chromosome M.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007007; P:inner mitochondrial membrane organization; IEA:EnsemblFungi.
DR   InterPro; IPR008839; MDM33_fungi.
DR   Pfam; PF05546; She9_MDM33; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q6FK33.
DR   SWISS-2DPAGE; Q6FK33.
KW   Coiled coil; Complete proteome; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; Reference proteome; Transit peptide;
KW   Transmembrane; Transmembrane helix.
FT   TRANSIT       1      ?       Mitochondrion. {ECO:0000255}.
FT   CHAIN         ?    405       Sensitive to high expression protein 9
FT                                homolog, mitochondrial.
FT                                /FTId=PRO_0000351053.
FT   TOPO_DOM      ?    281       Mitochondrial matrix. {ECO:0000255}.
FT   TRANSMEM    282    302       Helical. {ECO:0000255}.
FT   TOPO_DOM    303    381       Mitochondrial intermembrane.
FT                                {ECO:0000255}.
FT   TRANSMEM    382    402       Helical. {ECO:0000255}.
FT   TOPO_DOM    403    405       Mitochondrial matrix. {ECO:0000255}.
FT   COILED       76    118       {ECO:0000255}.
FT   COILED      161    194       {ECO:0000255}.
FT   COILED      230    261       {ECO:0000255}.
FT   COILED      321    347       {ECO:0000255}.
SQ   SEQUENCE   405 AA;  47733 MW;  5D0C513CE0B2A61F CRC64;
     MYSYRYLRPV SRSGRAILIQ RQAYLRNITF THFRCEENKS SASKRPTGNA LNTKLNELNG
     SLNNLWNKFL EGRGVFQHHA KNIRKSIQEA NKKIAEQEKE SKDAKINYKK DELTNEEIKD
     LPSERELHRK KWSRKLEFYL DSLQETLFTA TKALNDVTGY SSIQKLKNSI NLINEKLDAT
     RKARTDLKLQ YTKAIESRTL SQKQLNELLQ RKSSWSPSDL ENFTKLYKDD AINQQTEKEL
     KEKVRDIEKK EEQLTDDLYR AILTRYHEEQ IWSDKIRRTS TWGTFILMGF NLVLFIIFQL
     LLEPWKRRRL TGSFEGKVRH ALELHSQEQE TKIRDFLEEI KTKESNNIAN EQKTITKLSF
     WDKLRNTFQN STGLSLTQFN MLELTVTAIN SFLVGILFTL LLHAL
//

If you have problems or comments...

PBIL Back to PBIL home page