(data stored in ACNUC8465 zone)

SWISSPROT: EXO70_CANGA

ID   EXO70_CANGA             Reviewed;         623 AA.
AC   Q6FJW2;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   30-AUG-2017, entry version 74.
DE   RecName: Full=Exocyst complex protein EXO70;
GN   Name=EXO70; OrderedLocusNames=CAGL0M03113g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 /
OS   NRRL Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S.,
RA   Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E.,
RA   Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V.,
RA   Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C.,
RA   Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A.,
RA   Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A.,
RA   Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R.,
RA   Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H.,
RA   Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O.,
RA   Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A.,
RA   Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B.,
RA   Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A.,
RA   Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA   Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in the secretory pathway as part of the exocyst
CC       complex which tethers secretory vesicles to the sites of
CC       exocytosis. Also plays a role in the assembly of the exocyst (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Bud {ECO:0000250}. Bud neck {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EXO70 family. {ECO:0000305}.
DR   EMBL; CR380959; CAG62458.1; -; Genomic_DNA.
DR   RefSeq; XP_449482.1; XM_449482.1.
DR   ProteinModelPortal; Q6FJW2; -.
DR   SMR; Q6FJW2; -.
DR   STRING; 284593.XP_449482.1; -.
DR   EnsemblFungi; CAG62458; CAG62458; CAGL0M03113g.
DR   KEGG; cgr:CAGL0M03113g; -.
DR   CGD; CAL0136511; CAGL0M03113g.
DR   EuPathDB; FungiDB:CAGL0M03113g; -.
DR   eggNOG; KOG2344; Eukaryota.
DR   eggNOG; ENOG410YIGI; LUCA.
DR   HOGENOM; HOG000000807; -.
DR   InParanoid; Q6FJW2; -.
DR   KO; K07195; -.
DR   OMA; PRKHIKY; -.
DR   OrthoDB; EOG092C0ZIR; -.
DR   Proteomes; UP000002428; Chromosome M.
DR   GO; GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.
DR   GO; GO:0005934; C:cellular bud tip; IEA:EnsemblFungi.
DR   GO; GO:0000145; C:exocyst; IEA:EnsemblFungi.
DR   GO; GO:0000131; C:incipient cellular bud site; IEA:EnsemblFungi.
DR   GO; GO:0005886; C:plasma membrane; IEA:EnsemblFungi.
DR   GO; GO:0017049; F:GTP-Rho binding; IEA:EnsemblFungi.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:EnsemblFungi.
DR   GO; GO:0001927; P:exocyst assembly; IEA:EnsemblFungi.
DR   GO; GO:0051601; P:exocyst localization; IEA:EnsemblFungi.
DR   GO; GO:0006893; P:Golgi to plasma membrane transport; IEA:EnsemblFungi.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007266; P:Rho protein signal transduction; IEA:EnsemblFungi.
DR   InterPro; IPR016159; Cullin_repeat-like_dom.
DR   InterPro; IPR004140; Exo70.
DR   PANTHER; PTHR12542; PTHR12542; 1.
DR   Pfam; PF03081; Exo70; 1.
DR   SUPFAM; SSF74788; SSF74788; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q6FJW2.
DR   SWISS-2DPAGE; Q6FJW2.
KW   Complete proteome; Exocytosis; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN         1    623       Exocyst complex protein EXO70.
FT                                /FTId=PRO_0000118967.
SQ   SEQUENCE   623 AA;  71155 MW;  A66E02D0846BB80E CRC64;
     MNEIDVDEAD ILVLSQGLEK TSRLTHQVNK SLAKISKTSA QSSQLFGPIL ARNNVLKTLQ
     RNIDSTLNSV ASVKDLANEA SKHEVLLRKG IASLGLKPFT VELHKLEDMY QDMSVGNSRH
     TENAEFHGIL KHLKEMITSS EEQLELEFIQ ILKRIEPFDP QINMEKKIPF PYYSDEDISQ
     MLIIFNYFYV KSEDSRMQDI FIRERGDQML KSMAFMEPFA KKVTSSKNAP YEKGSSGFIN
     YTEAVLGFIA NERSLIDDVF SQFAEIKPRV LRNILDPIVA AFCKVLMSDL IFVKSNIDNA
     GLFSFELTEC ISGVQKSVKG MNLKNQMQLI DADKQVKDVT RSLFKDTVDR IKSKTNQMTT
     IPSDNGVTEA TVDTMSRLRK FSEYKTGCLA AMESISRDVW LSKSFREKEY TIQSAAIADN
     ETAASLLSCF LSDCIDTLVA NLERRAQTIL MPNQEPDVAN PNSARNKFKQ RIGFLVLMNM
     TLVEQIVEKS ELSVMLGNLG KARIEKLKKR YVNYLVADWK DLTVNLMDTV VIDSVGKKSK
     DKEQIKEKFR RFNEGFEDLI SRTKQYKLSD PALKRLLKSE IVALLMPMYD RFYGRYKDSF
     KNPRKHIKYT PDDITNVISQ TLR
//

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