(data stored in ACNUC8465 zone)

SWISSPROT: IML2_CANGA

ID   IML2_CANGA              Reviewed;         743 AA.
AC   Q6FJV9;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   30-AUG-2017, entry version 74.
DE   RecName: Full=Mitochondrial outer membrane protein IML2;
GN   Name=IML2; OrderedLocusNames=CAGL0M03179g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 /
OS   NRRL Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S.,
RA   Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E.,
RA   Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V.,
RA   Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C.,
RA   Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A.,
RA   Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A.,
RA   Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R.,
RA   Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H.,
RA   Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O.,
RA   Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A.,
RA   Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B.,
RA   Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A.,
RA   Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA   Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: May be involved in mitochondrial DNA stability.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IML2 family. {ECO:0000305}.
DR   EMBL; CR380959; CAG62461.1; -; Genomic_DNA.
DR   RefSeq; XP_449485.1; XM_449485.1.
DR   SMR; Q6FJV9; -.
DR   STRING; 284593.XP_449485.1; -.
DR   EnsemblFungi; CAG62461; CAG62461; CAGL0M03179g.
DR   KEGG; cgr:CAGL0M03179g; -.
DR   CGD; CAL0136953; CAGL0M03179g.
DR   EuPathDB; FungiDB:CAGL0M03179g; -.
DR   eggNOG; ENOG410ITR2; Eukaryota.
DR   eggNOG; ENOG410Y5QW; LUCA.
DR   HOGENOM; HOG000066085; -.
DR   InParanoid; Q6FJV9; -.
DR   OMA; ALSESYM; -.
DR   OrthoDB; EOG092C0XWM; -.
DR   Proteomes; UP000002428; Chromosome M.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0071218; P:cellular response to misfolded protein; IEA:EnsemblFungi.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR019412; OMP_Iml2/TPR_39.
DR   InterPro; IPR011990; TPR-like_helical_dom.
DR   Pfam; PF10300; DUF3808; 1.
DR   SUPFAM; SSF48452; SSF48452; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q6FJV9.
DR   SWISS-2DPAGE; Q6FJV9.
KW   Complete proteome; Membrane; Mitochondrion;
KW   Mitochondrion outer membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN         1    743       Mitochondrial outer membrane protein
FT                                IML2.
FT                                /FTId=PRO_0000333345.
FT   TRANSMEM    305    325       Helical. {ECO:0000255}.
FT   TRANSMEM    347    367       Helical. {ECO:0000255}.
SQ   SEQUENCE   743 AA;  83498 MW;  9264820C0C2DD029 CRC64;
     MFKVFGALSG KGSSDSNGNS TRSSINEKRT KLILKEANDF EIALRAMDYV LDDRTEEGLA
     LLRENEKVNG QNQTITVLAR GVIEFLQATL SFEMEEIKNA SNTLAKAEQL SWKSRTEAQK
     SGIRNSSIYP PGTVYAVTYT ESCLLHALLM LFTESMMDAA KALLKLRKAY SMLHEIMEVV
     KKSELSRKVS SSSAVSIQSN GSFVSEEATF VSADIPYQLS ETESNDPELW AFAEKIYKMR
     KLRLSGAHIG NTPAISRLRS GLGLSASNKS EELANSEQSV LSDEAAERQA TIDEFIHSGV
     NLCYGILQVV LSLIPPAIGA VLSIVGFRGS REEGLRLIWK ATKDRNVHGC IGLLGLMFYY
     DGPFQFTDVD FDIPPALSNT KTSDSDTDRD GSISIDEMDG HALLHPGPIL EEALLHARAL
     FPNSALWLLN EARMLSSRGR LPEAIELLDS IDVESIHMRQ VKGLLVFDKA ITLVHMQEYE
     RAATNLLSLL KISDWSHAFY TYFAGCCYLE NWRMAQMGFI KDDKLEFYRE KAEELIFSAP
     KLLGKKTFKS KNLPLDRFML RKVEQFKATQ KKLGVKNILD AIGTSPIREI TYFYNGYNRM
     SKSDLEIAQK MLTSYHNPAI DQHDPDQELI KNLLLSLTMR RLGDVESGVK LLDEKVLPSI
     YYMQNGKVKY IKKTEDPWAY PTALYERALF TWKLDGVDNL SECRHWLVTA QNYAGDYELS
     TRVGMKIKAA LDRVEESLQH GTA
//

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