(data stored in ACNUC8465 zone)

SWISSPROT: VAC8_CANGA

ID   VAC8_CANGA              Reviewed;         582 AA.
AC   Q6FJV1;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   30-AUG-2017, entry version 81.
DE   RecName: Full=Vacuolar protein 8;
GN   Name=VAC8; OrderedLocusNames=CAGL0M03355g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 /
OS   NRRL Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S.,
RA   Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E.,
RA   Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V.,
RA   Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C.,
RA   Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A.,
RA   Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A.,
RA   Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R.,
RA   Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H.,
RA   Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O.,
RA   Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A.,
RA   Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B.,
RA   Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A.,
RA   Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA   Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Functions in both vacuole inheritance and protein
CC       targeting from the cytoplasm to vacuole. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000250}; Lipid-anchor
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the beta-catenin family. {ECO:0000305}.
DR   EMBL; CR380959; CAG62469.1; -; Genomic_DNA.
DR   RefSeq; XP_449493.1; XM_449493.1.
DR   ProteinModelPortal; Q6FJV1; -.
DR   STRING; 284593.XP_449493.1; -.
DR   EnsemblFungi; CAG62469; CAG62469; CAGL0M03355g.
DR   KEGG; cgr:CAGL0M03355g; -.
DR   CGD; CAL0137157; CAGL0M03355g.
DR   EuPathDB; FungiDB:CAGL0M03355g; -.
DR   eggNOG; KOG0167; Eukaryota.
DR   eggNOG; ENOG410XRTN; LUCA.
DR   HOGENOM; HOG000177331; -.
DR   InParanoid; Q6FJV1; -.
DR   KO; K08332; -.
DR   OMA; ATFQHIA; -.
DR   OrthoDB; EOG092C1KQT; -.
DR   Proteomes; UP000002428; Chromosome M.
DR   GO; GO:0000329; C:fungal-type vacuole membrane; IEA:EnsemblFungi.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:EnsemblFungi.
DR   GO; GO:0071563; C:Myo2p-Vac17p-Vac8p transport complex; IEA:EnsemblFungi.
DR   GO; GO:0071561; C:nucleus-vacuole junction; IEA:EnsemblFungi.
DR   GO; GO:0043495; F:protein anchor; IEA:EnsemblFungi.
DR   GO; GO:0071255; P:CVT vesicle assembly; IEA:EnsemblFungi.
DR   GO; GO:0016236; P:macroautophagy; IEA:EnsemblFungi.
DR   GO; GO:0071562; P:nucleus-vacuole junction assembly; IEA:EnsemblFungi.
DR   GO; GO:0042144; P:vacuole fusion, non-autophagic; IEA:EnsemblFungi.
DR   GO; GO:0000011; P:vacuole inheritance; IEA:EnsemblFungi.
DR   Gene3D; 1.25.10.10; -; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000225; Armadillo.
DR   Pfam; PF00514; Arm; 8.
DR   SMART; SM00185; ARM; 9.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   PROSITE; PS50176; ARM_REPEAT; 7.
PE   3: Inferred from homology;
DR   PRODOM; Q6FJV1.
DR   SWISS-2DPAGE; Q6FJV1.
KW   Complete proteome; Lipoprotein; Membrane; Myristate; Palmitate;
KW   Reference proteome; Repeat; Vacuole.
FT   INIT_MET      1      1       Removed. {ECO:0000250}.
FT   CHAIN         2    582       Vacuolar protein 8.
FT                                /FTId=PRO_0000256209.
FT   REPEAT       37     74       ARM 1.
FT   REPEAT       75    114       ARM 2.
FT   REPEAT      116    155       ARM 3.
FT   REPEAT      157    196       ARM 4.
FT   REPEAT      198    237       ARM 5.
FT   REPEAT      239    280       ARM 6.
FT   REPEAT      282    321       ARM 7.
FT   REPEAT      323    363       ARM 8.
FT   REPEAT      407    446       ARM 9.
FT   LIPID         2      2       N-myristoyl glycine. {ECO:0000250}.
FT   LIPID         4      4       S-palmitoyl cysteine. {ECO:0000255}.
FT   LIPID         5      5       S-palmitoyl cysteine. {ECO:0000255}.
FT   LIPID         7      7       S-palmitoyl cysteine. {ECO:0000255}.
SQ   SEQUENCE   582 AA;  63901 MW;  CD39E0C773D870E3 CRC64;
     MGGCCSCFRD SSDDVSVLPI TDNEREAVTL LLGYLEDKDR LDFYSGGPLK ALTTLVYSDN
     LNLQRSAALA FAEVTEKYVR QVSRDVLEPI LILLQSQDPQ IQVAACAALG NLAVNNENKL
     LIVDMGGLEP LINQMMGTNV EVQCNAVGCI TNLATRDDNK HKIATSGALV PLTKLAKSKH
     IRVQRNATGA LLNMTHSEEN RRELVNAGAV PVLVSLLSSN DPDVQYYCTT ALSNIAVDEA
     NRKKLAQTEP RLVSKLVSLM DSPSSRVKCQ ATLALRNLAS DTSYQLEIVR AGGLPHLVNL
     IQSESVPLIL ASVACIRNIS IHPLNEGLIV DAGFLPPLVK LLDYRDSEEI QCHAVSTLRN
     LAASSEKNRK EFFESGAVKK CKELALDSPV SVQSEISACF AILALADVSK QDLLDADILQ
     ALIPMTFSTN QEVSGNAAAA LANLCSRIDN YSKIISSWDQ PKEGIRGFLK RFLQSNYATF
     EHIALWAILQ LSESHNDKVI YLIKNDKEII NSVRKMADVT YDRLQKSGVD VNKNGNSEER
     GDNEDHQSNN DRNLANSTSS DQYEDASMEL YNITQQILQF LD
//

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