(data stored in ACNUC8465 zone)

SWISSPROT: MBF1_CANGA

ID   MBF1_CANGA              Reviewed;         151 AA.
AC   Q6FJN0;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   30-AUG-2017, entry version 81.
DE   RecName: Full=Multiprotein-bridging factor 1;
GN   Name=MBF1; OrderedLocusNames=CAGL0M04983g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 /
OS   NRRL Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S.,
RA   Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E.,
RA   Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V.,
RA   Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C.,
RA   Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A.,
RA   Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A.,
RA   Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R.,
RA   Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H.,
RA   Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O.,
RA   Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A.,
RA   Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B.,
RA   Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A.,
RA   Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA   Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Transcriptional coactivator that stimulates
CC       transcriptional activity by bridging regulatory proteins and TBP,
CC       thereby recruiting TBP to promoters occupied by DNA-binding
CC       regulators. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MBF1 family. {ECO:0000305}.
DR   EMBL; CR380959; CAG62540.1; -; Genomic_DNA.
DR   RefSeq; XP_449564.1; XM_449564.1.
DR   ProteinModelPortal; Q6FJN0; -.
DR   SMR; Q6FJN0; -.
DR   STRING; 284593.XP_449564.1; -.
DR   EnsemblFungi; CAG62540; CAG62540; CAGL0M04983g.
DR   KEGG; cgr:CAGL0M04983g; -.
DR   CGD; CAL0136719; CAGL0M04983g.
DR   EuPathDB; FungiDB:CAGL0M04983g; -.
DR   eggNOG; KOG3398; Eukaryota.
DR   eggNOG; COG1813; LUCA.
DR   HOGENOM; HOG000195726; -.
DR   InParanoid; Q6FJN0; -.
DR   KO; K03627; -.
DR   OMA; IADYECG; -.
DR   OrthoDB; EOG092C5XAS; -.
DR   Proteomes; UP000002428; Chromosome M.
DR   GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR   GO; GO:0005730; C:nucleolus; IEA:EnsemblFungi.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:EnsemblFungi.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:EnsemblFungi.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom.
DR   InterPro; IPR013729; MBF1_N.
DR   Pfam; PF01381; HTH_3; 1.
DR   Pfam; PF08523; MBF1; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q6FJN0.
DR   SWISS-2DPAGE; Q6FJN0.
KW   Activator; Complete proteome; DNA-binding; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN         1    151       Multiprotein-bridging factor 1.
FT                                /FTId=PRO_0000149804.
FT   DOMAIN       85    139       HTH cro/C1-type. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00257}.
FT   DNA_BIND     96    115       H-T-H motif. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00257}.
SQ   SEQUENCE   151 AA;  16356 MW;  67CC8BFD3C202D64 CRC64;
     MSDWESHTVI GQKARAGGSG PRANVARTQG QINAARRQGL VLSVDKKYGT ANTKGDAEGQ
     RLTKVDRETD IVKPKKLDAN VGKTIARVRT EKKMSQKDLA TKINEKPTVI NDYEAGRAIP
     NQQVLGKMER ALGVKLRGKA IGEPLGGPKK K
//

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