(data stored in ACNUC8465 zone)

SWISSPROT: CIAO1_CANGA

ID   CIAO1_CANGA             Reviewed;         337 AA.
AC   Q6FJ73;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   30-AUG-2017, entry version 91.
DE   RecName: Full=Probable cytosolic iron-sulfur protein assembly protein 1 {ECO:0000255|HAMAP-Rule:MF_03037};
GN   Name=CIA1 {ECO:0000255|HAMAP-Rule:MF_03037};
GN   OrderedLocusNames=CAGL0M08646g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 /
OS   NRRL Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S.,
RA   Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E.,
RA   Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V.,
RA   Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C.,
RA   Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A.,
RA   Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A.,
RA   Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R.,
RA   Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H.,
RA   Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O.,
RA   Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A.,
RA   Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B.,
RA   Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A.,
RA   Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA   Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Essential component of the cytosolic iron-sulfur (Fe/S)
CC       protein assembly machinery. Required for the maturation of
CC       extramitochondrial Fe/S proteins. {ECO:0000255|HAMAP-
CC       Rule:MF_03037}.
CC   -!- SUBUNIT: Interacts with NAR1. {ECO:0000255|HAMAP-Rule:MF_03037}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03037}.
CC       Nucleus {ECO:0000255|HAMAP-Rule:MF_03037}. Note=Preferentially
CC       localized to the nucleus. {ECO:0000255|HAMAP-Rule:MF_03037}.
CC   -!- SIMILARITY: Belongs to the WD repeat CIA1 family.
CC       {ECO:0000255|HAMAP-Rule:MF_03037}.
DR   EMBL; CR380959; CAG62697.1; -; Genomic_DNA.
DR   RefSeq; XP_449721.1; XM_449721.1.
DR   ProteinModelPortal; Q6FJ73; -.
DR   SMR; Q6FJ73; -.
DR   STRING; 284593.XP_449721.1; -.
DR   EnsemblFungi; CAG62697; CAG62697; CAGL0M08646g.
DR   KEGG; cgr:CAGL0M08646g; -.
DR   CGD; CAL0136897; CAGL0M08646g.
DR   EuPathDB; FungiDB:CAGL0M08646g; -.
DR   eggNOG; KOG0645; Eukaryota.
DR   eggNOG; ENOG410XRMA; LUCA.
DR   HOGENOM; HOG000208901; -.
DR   InParanoid; Q6FJ73; -.
DR   OMA; VWKCVCT; -.
DR   OrthoDB; EOG092C4BLN; -.
DR   Proteomes; UP000002428; Chromosome M.
DR   GO; GO:0097361; C:CIA complex; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:EnsemblFungi.
DR   GO; GO:0002098; P:tRNA wobble uridine modification; IEA:EnsemblFungi.
DR   Gene3D; 2.130.10.10; -; 2.
DR   HAMAP; MF_03037; ciao1; 1.
DR   InterPro; IPR028608; CIAO1/Cia1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR017986; WD40_repeat_dom.
DR   Pfam; PF00400; WD40; 6.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 6.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q6FJ73.
DR   SWISS-2DPAGE; Q6FJ73.
KW   Complete proteome; Cytoplasm; Nucleus; Reference proteome; Repeat;
KW   WD repeat.
FT   CHAIN         1    337       Probable cytosolic iron-sulfur protein
FT                                assembly protein 1.
FT                                /FTId=PRO_0000382510.
FT   REPEAT       11     50       WD 1.
FT   REPEAT       57     96       WD 2.
FT   REPEAT      109    148       WD 3.
FT   REPEAT      155    194       WD 4.
FT   REPEAT      199    240       WD 5.
FT   REPEAT      252    290       WD 6.
FT   REPEAT      301    337       WD 7.
SQ   SEQUENCE   337 AA;  38019 MW;  E6767EE6E9C3DD7E CRC64;
     MPLQLAKSLK LHNDKVWSID FEPVRGLLAT GSTDRAIKVL QLKNGKENLL DVLDDTVHKK
     AVRSVAWRPH SDLLAAGSFD STISIWTQSD LDLEEGAKLE MELLAIIEGH ENEVKGISWS
     QDGCLLATCS RDKSVWIWET DEAGEEYECI SVLQEHSQDV KHVVWHTKHN LLASSSYDDT
     VRIWKDYDDD WECAAVLTGH EGTIWCSDFS KEEDPIRLCS GSDDSTVRVW KYIGDDEDDQ
     QEWVCESTLP NAHRSQIYGV AWSPSGRIAS VGADGVLAVY KEKQNDSEVS EWEISATYKA
     AHTVYEINTV KWVNIDGKEM LITAGDDGRV NLWNYQD
//

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