(data stored in ACNUC8465 zone)

SWISSPROT: PALB_CANGA

ID   PALB_CANGA              Reviewed;         713 AA.
AC   Q6FJ28;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   08-MAY-2019, entry version 71.
DE   RecName: Full=Calpain-like protease palB/RIM13;
DE            EC=3.4.22.-;
DE   AltName: Full=Cysteine protease RIM13;
GN   Name=RIM13; OrderedLocusNames=CAGL0M09669g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 /
OS   NRRL Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S.,
RA   Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E.,
RA   Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V.,
RA   Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C.,
RA   Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A.,
RA   Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A.,
RA   Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R.,
RA   Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H.,
RA   Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O.,
RA   Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A.,
RA   Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B.,
RA   Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A.,
RA   Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA   Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for the proteolytic cleavage of the
CC       transcription factor RIM101 in response to alkaline ambient pH.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the peptidase C2 family. PalB/RIM13
CC       subfamily. {ECO:0000305}.
DR   EMBL; CR380959; CAG62744.1; -; Genomic_DNA.
DR   RefSeq; XP_449766.1; XM_449766.1.
DR   STRING; 5478.XP_449766.1; -.
DR   PRIDE; Q6FJ28; -.
DR   EnsemblFungi; CAG62744; CAG62744; CAGL0M09669g.
DR   GeneID; 2891330; -.
DR   KEGG; cgr:CAGL0M09669g; -.
DR   CGD; CAL0136251; CAGL0M09669g.
DR   EuPathDB; FungiDB:CAGL0M09669g; -.
DR   eggNOG; KOG0045; Eukaryota.
DR   eggNOG; ENOG410XP0B; LUCA.
DR   InParanoid; Q6FJ28; -.
DR   OMA; WLLLESH; -.
DR   Proteomes; UP000002428; Chromosome M.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   SUPFAM; SSF54001; SSF54001; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q6FJ28.
DR   SWISS-2DPAGE; Q6FJ28.
KW   Complete proteome; Hydrolase; Protease; Reference proteome;
KW   Thiol protease.
FT   CHAIN         1    713       Calpain-like protease palB/RIM13.
FT                                /FTId=PRO_0000207739.
FT   DOMAIN       74    325       Calpain catalytic.
FT   ACT_SITE    131    131       {ECO:0000250}.
FT   ACT_SITE    279    279       {ECO:0000250}.
FT   ACT_SITE    308    308       {ECO:0000250}.
SQ   SEQUENCE   713 AA;  82519 MW;  F3D47DF1E0405685 CRC64;
     MNVDRCWEQY YKTLKLIYLE ENKETCQREI DHLVDTAIEL KEKTYSNAVL DLGRQFREVC
     PKARIMWKTS SIAGNFYPPI SISDIYSPVI ANVFDQTTRL ECRRQEYSLR MPLQEEPNFT
     GIQQHAQVSD CSLVVSLINI NRYKTTMPVV KQVAENLYAT NLYFNGAQRR LVLVSTENIP
     TMQDDPTKQM SVHSANKINK ILELGLLKLT SLSYHSEGSN TAIDTYRLCG WIPDISSINE
     FNFLKVHKAF SRGECLIAMG TGGFVPKENI FGVKLRKYHD YAVLDIDMIN EVVTLRDPLI
     SDTLLTINFD SIRKYFLQVY CNWDSSKLFM FTKDTQIFYS DKKFNPYQTL AGKPTFYLKN
     NSDRDEYAWV LLEFHLDKNN NTTAYLQEIP DRISTVRLGY NDNSAETGFQ LIKIRLKPKQ
     CIWYFCYSST DKMLTFHTYS TSSDVVFVRS KMPGCDFDVT ECAILPENIV PMQYPNHSET
     DIYYLASIDF SIEGEPGITI ITDMVVCLET DDDLVNFQMF HWDDLDFNSP IYDEFYMNER
     MFEKKDLPLT SGERYRIVAS TARPPISKGY QCAVSGINIH ADYPCSYKLR ESDVRYNSMM
     FKLPHVFTLA STGITKISLV NRNKYNKVFM RIYPQTQEDY RYNYRVISAD TGEDLVKPGN
     NIQKLYGGIV IKEFLVSDQT NLELHLSFQD NGRVPVELKC QLYVGSVKII TLS
//

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