(data stored in ACNUC6288 zone)

SWISSPROT: SLT11_DEBHA

ID   SLT11_DEBHA             Reviewed;         359 AA.
AC   Q6BMD1;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 2.
DT   10-APR-2019, entry version 81.
DE   RecName: Full=Pre-mRNA-splicing factor SLT11;
GN   Name=SLT11; OrderedLocusNames=DEHA2F06490g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC
OS   0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S.,
RA   Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E.,
RA   Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V.,
RA   Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C.,
RA   Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A.,
RA   Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A.,
RA   Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R.,
RA   Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H.,
RA   Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O.,
RA   Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A.,
RA   Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B.,
RA   Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A.,
RA   Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA   Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in pre-mRNA splicing. Facilitates the
CC       cooperative formation of U2/U6 helix II in association with stem
CC       II in the spliceosome. Binds to RNA (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SLT11 family. {ECO:0000305}.
DR   EMBL; CR382138; CAG88972.2; -; Genomic_DNA.
DR   RefSeq; XP_460640.2; XM_460640.1.
DR   SMR; Q6BMD1; -.
DR   STRING; 4959.XP_460640.2; -.
DR   PRIDE; Q6BMD1; -.
DR   EnsemblFungi; CAG88972; CAG88972; DEHA2F06490g.
DR   GeneID; 2903151; -.
DR   KEGG; dha:DEHA2F06490g; -.
DR   HOGENOM; HOG000093781; -.
DR   InParanoid; Q6BMD1; -.
DR   KO; K12872; -.
DR   OMA; VCSHMSH; -.
DR   OrthoDB; 1272857at2759; -.
DR   Proteomes; UP000000599; Chromosome F.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR   CDD; cd12265; RRM_SLT11; 1.
DR   Gene3D; 3.30.70.330; -; 1.
DR   InterPro; IPR039171; Cwc2/Slt11.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR034356; Slt11-like_RRM.
DR   PANTHER; PTHR14089; PTHR14089; 1.
DR   SUPFAM; SSF54928; SSF54928; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q6BMD1.
DR   SWISS-2DPAGE; Q6BMD1.
KW   Complete proteome; mRNA processing; mRNA splicing; Nucleus;
KW   Reference proteome; RNA-binding; Spliceosome.
FT   CHAIN         1    359       Pre-mRNA-splicing factor SLT11.
FT                                /FTId=PRO_0000212426.
SQ   SEQUENCE   359 AA;  40173 MW;  AA6E9506B99F5C3D CRC64;
     MSDEFPAICD SCCGPDKHIK MMRQANGEEC KVCTRPFTVF RWNPNNGTNK SKKTIICMTC
     ARARNCCQSC MLDITYGIPL EIRDTALKMA GLEHASQIKS SNTSQNREVK AIMADKQEAK
     YNNEDNDVNK SNDRSEMARD ILSKLSEKLN GNTNALIKKA PKNSKTTKKN EIINVKNADI
     SKILGKLPLG GSIVVPETTP ELSSFFLFGF SDDIPQYIIS DFCNKFGKIK SLSIVHRAKC
     GYVVFTTRKA AESFATTIME NGLNKNTATP GLLILNNKYP VRVSWGKQKP LVTTNEECHK
     LSLVITKVMR QLAEKDKIFE DQKITKKAKN HKTSSDANEH SSNTASTQHY KALRPDFEL
//

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