(data stored in SCRATCH zone)

SWISSPROT: NRDR_CHLAB

ID   NRDR_CHLAB              Reviewed;         152 AA.
AC   Q5L6Q6;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-JUN-2005, sequence version 1.
DT   11-DEC-2019, entry version 76.
DE   RecName: Full=Transcriptional repressor NrdR {ECO:0000255|HAMAP-Rule:MF_00440};
GN   Name=nrdR {ECO:0000255|HAMAP-Rule:MF_00440}; OrderedLocusNames=CAB207;
OS   Chlamydia abortus (strain DSM 27085 / S26/3) (Chlamydophila abortus).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=218497;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 27085 / S26/3;
RX   PubMed=15837807; DOI=10.1101/gr.3684805;
RA   Thomson N.R., Yeats C., Bell K., Holden M.T.G., Bentley S.D.,
RA   Livingstone M., Cerdeno-Tarraga A.-M., Harris B., Doggett J., Ormond D.,
RA   Mungall K., Clarke K., Feltwell T., Hance Z., Sanders M., Quail M.A.,
RA   Price C., Barrell B.G., Parkhill J., Longbottom D.;
RT   "The Chlamydophila abortus genome sequence reveals an array of variable
RT   proteins that contribute to interspecies variation.";
RL   Genome Res. 15:629-640(2005).
CC   -!- FUNCTION: Negatively regulates transcription of bacterial
CC       ribonucleotide reductase nrd genes and operons by binding to NrdR-
CC       boxes. {ECO:0000255|HAMAP-Rule:MF_00440}.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00440};
CC       Note=Binds 1 zinc ion. {ECO:0000255|HAMAP-Rule:MF_00440};
CC   -!- SIMILARITY: Belongs to the NrdR family. {ECO:0000255|HAMAP-
CC       Rule:MF_00440}.
DR   EMBL; CR848038; CAH63665.1; -; Genomic_DNA.
DR   RefSeq; WP_006342890.1; NC_004552.2.
DR   STRING; 218497.CAB207; -.
DR   PRIDE; Q5L6Q6; -.
DR   EnsemblBacteria; CAH63665; CAH63665; CAB207.
DR   GeneID; 12242669; -.
DR   KEGG; cab:CAB207; -.
DR   eggNOG; ENOG4108Z11; Bacteria.
DR   eggNOG; COG1327; LUCA.
DR   HOGENOM; HOG000097653; -.
DR   KO; K07738; -.
DR   OMA; RFTTYET; -.
DR   OrthoDB; 1551627at2; -.
DR   BioCyc; CABO218497:G1GI1-227-MONOMER; -.
DR   Proteomes; UP000001012; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00440; NrdR; 1.
DR   InterPro; IPR005144; ATP-cone_dom.
DR   InterPro; IPR003796; RNR_NrdR-like.
DR   PANTHER; PTHR30455; PTHR30455; 1.
DR   Pfam; PF03477; ATP-cone; 1.
DR   TIGRFAMs; TIGR00244; TIGR00244; 1.
DR   PROSITE; PS51161; ATP_CONE; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q5L6Q6.
DR   SWISS-2DPAGE; Q5L6Q6.
KW   ATP-binding; DNA-binding; Metal-binding; Nucleotide-binding; Repressor;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..152
FT                   /note="Transcriptional repressor NrdR"
FT                   /id="PRO_0000230862"
FT   DOMAIN          48..138
FT                   /note="ATP-cone"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00440"
FT   ZN_FING         3..34
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00440"
SQ   SEQUENCE   152 AA;  17400 MW;  9DCA02260375C505 CRC64;
     MQCPFCNHGE LKVIDSRNAP EANAIKRRRE CLNCGQRFTT FETVELTLQV LKRDGRYENF
     QESKLINGLN AASSHTRIGQ DQVHAIASNV KSELLGKQNR EISTKEIGEL VMKYLKKADM
     IAYIRFACVY RRFKDVGELM EVLLSATPDM EK
//

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