(data stored in ACNUC7421 zone)

SWISSPROT: YACG_PSEHT

ID   YACG_PSEHT              Reviewed;          76 AA.
AC   Q3IID3;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   05-JUL-2017, entry version 77.
DE   RecName: Full=DNA gyrase inhibitor YacG {ECO:0000255|HAMAP-Rule:MF_00649};
GN   Name=yacG {ECO:0000255|HAMAP-Rule:MF_00649};
GN   OrderedLocusNames=PSHAa0377;
OS   Pseudoalteromonas haloplanktis (strain TAC 125).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Pseudoalteromonadaceae; Pseudoalteromonas.
OX   NCBI_TaxID=326442;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TAC 125;
RX   PubMed=16169927; DOI=10.1101/gr.4126905;
RA   Medigue C., Krin E., Pascal G., Barbe V., Bernsel A., Bertin P.N.,
RA   Cheung F., Cruveiller S., D'Amico S., Duilio A., Fang G., Feller G.,
RA   Ho C., Mangenot S., Marino G., Nilsson J., Parrilli E., Rocha E.P.C.,
RA   Rouy Z., Sekowska A., Tutino M.L., Vallenet D., von Heijne G.,
RA   Danchin A.;
RT   "Coping with cold: the genome of the versatile marine Antarctica
RT   bacterium Pseudoalteromonas haloplanktis TAC125.";
RL   Genome Res. 15:1325-1335(2005).
CC   -!- FUNCTION: Inhibits all the catalytic activities of DNA gyrase by
CC       preventing its interaction with DNA. Acts by binding directly to
CC       the C-terminal domain of GyrB, which probably disrupts DNA binding
CC       by the gyrase. {ECO:0000255|HAMAP-Rule:MF_00649}.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00649};
CC       Note=Binds 1 zinc ion. {ECO:0000255|HAMAP-Rule:MF_00649};
CC   -!- SUBUNIT: Interacts with GyrB. {ECO:0000255|HAMAP-Rule:MF_00649}.
CC   -!- SIMILARITY: Belongs to the DNA gyrase inhibitor YacG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00649}.
DR   EMBL; CR954246; CAI85475.1; -; Genomic_DNA.
DR   RefSeq; WP_011327088.1; NC_007481.1.
DR   ProteinModelPortal; Q3IID3; -.
DR   SMR; Q3IID3; -.
DR   STRING; 326442.PSHAa0377; -.
DR   EnsemblBacteria; CAI85475; CAI85475; PSHAa0377.
DR   GeneID; 32566154; -.
DR   KEGG; pha:PSHAa0377; -.
DR   eggNOG; ENOG41067SF; Bacteria.
DR   eggNOG; COG3024; LUCA.
DR   HOGENOM; HOG000255917; -.
DR   KO; K09862; -.
DR   OMA; WAAEEHK; -.
DR   OrthoDB; POG091H04DF; -.
DR   Proteomes; UP000006843; Chromosome I.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 3.30.50.10; -; 1.
DR   HAMAP; MF_00649; DNA_gyrase_inhibitor_YacG; 1.
DR   InterPro; IPR005584; DNA_gyrase_inhibitor_YacG.
DR   InterPro; IPR013088; Znf_NHR/GATA.
DR   Pfam; PF03884; YacG; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q3IID3.
DR   SWISS-2DPAGE; Q3IID3.
KW   Complete proteome; Metal-binding; Reference proteome; Zinc.
FT   CHAIN         1     76       DNA gyrase inhibitor YacG.
FT                                /FTId=PRO_1000056984.
FT   METAL         7      7       Zinc. {ECO:0000255|HAMAP-Rule:MF_00649}.
FT   METAL        10     10       Zinc. {ECO:0000255|HAMAP-Rule:MF_00649}.
FT   METAL        26     26       Zinc. {ECO:0000255|HAMAP-Rule:MF_00649}.
FT   METAL        30     30       Zinc. {ECO:0000255|HAMAP-Rule:MF_00649}.
SQ   SEQUENCE   76 AA;  8805 MW;  DC4DE8D46FE7CC17 CRC64;
     MPTIVNCPTC KSKVEWSEQS PHRPFCSKRC QLIDLGEWSF ENNRISAPIT SAEDFSQDMI
     EDIEAMMAKN EDDFFK
//

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