(data stored in ACNUC7421 zone)

SWISSPROT: Q3III3_PSEHT

ID   Q3III3_PSEHT            Unreviewed;       281 AA.
AC   Q3III3;
DT   08-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   08-NOV-2005, sequence version 1.
DT   07-JUN-2017, entry version 74.
DE   SubName: Full=Nicotinate-nucleotide pyrophosphorylase {ECO:0000313|EMBL:CAI85484.1};
DE            EC=2.4.2.19 {ECO:0000313|EMBL:CAI85484.1};
GN   Name=nadC {ECO:0000313|EMBL:CAI85484.1};
GN   OrderedLocusNames=PSHAa0386 {ECO:0000313|EMBL:CAI85484.1};
OS   Pseudoalteromonas haloplanktis (strain TAC 125).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Pseudoalteromonadaceae; Pseudoalteromonas.
OX   NCBI_TaxID=326442 {ECO:0000313|EMBL:CAI85484.1, ECO:0000313|Proteomes:UP000006843};
RN   [1] {ECO:0000313|EMBL:CAI85484.1, ECO:0000313|Proteomes:UP000006843}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TAC 125 {ECO:0000313|Proteomes:UP000006843};
RX   PubMed=16169927; DOI=10.1101/gr.4126905;
RA   Medigue C., Krin E., Pascal G., Barbe V., Bernsel A., Bertin P.,
RA   Cheung F., Cruveiller S., Damico S., Duilio A., Fang G., Feller G.,
RA   Mangenot S., Marino G., Nilsson J., Parilli E., Rocha E., Rouy Z.,
RA   Sekowska A., Tutino M.L., Vallenet D., von Heijne G., Danchin A.;
RT   "Coping with cold: the genome of the versatile marine Antarctica
RT   bacterium Pseudoalteromonas haloplanktis TAC125.";
RL   Genome Res. 15:1325-1335(2005).
CC   -!- SIMILARITY: Belongs to the NadC/ModD family.
CC       {ECO:0000256|PIRNR:PIRNR006250}.
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DR   EMBL; CR954246; CAI85484.1; -; Genomic_DNA.
DR   RefSeq; WP_011327097.1; NC_007481.1.
DR   ProteinModelPortal; Q3III3; -.
DR   STRING; 326442.PSHAa0386; -.
DR   EnsemblBacteria; CAI85484; CAI85484; PSHAa0386.
DR   KEGG; pha:PSHAa0386; -.
DR   PATRIC; fig|326442.8.peg.370; -.
DR   eggNOG; ENOG4105D18; Bacteria.
DR   eggNOG; COG0157; LUCA.
DR   HOGENOM; HOG000224022; -.
DR   KO; K00767; -.
DR   OMA; VIMLDNM; -.
DR   OrthoDB; POG091H05QJ; -.
DR   Proteomes; UP000006843; Chromosome I.
DR   GO; GO:0004514; F:nicotinate-nucleotide diphosphorylase (carboxylating) activity; IEA:UniProtKB-EC.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
DR   CDD; cd01572; QPRTase; 1.
DR   Gene3D; 3.20.20.70; -; 1.
DR   Gene3D; 3.90.1170.20; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR004393; NadC.
DR   InterPro; IPR027277; NadC/ModD.
DR   InterPro; IPR002638; Quinolinate_PRibosylTrfase_C.
DR   InterPro; IPR022412; Quinolinate_PRibosylTrfase_N.
DR   PANTHER; PTHR32179; PTHR32179; 1.
DR   Pfam; PF01729; QRPTase_C; 1.
DR   Pfam; PF02749; QRPTase_N; 1.
DR   PIRSF; PIRSF006250; NadC_ModD; 1.
DR   SUPFAM; SSF51690; SSF51690; 1.
DR   TIGRFAMs; TIGR00078; nadC; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q3III3.
DR   SWISS-2DPAGE; Q3III3.
KW   Complete proteome {ECO:0000313|Proteomes:UP000006843};
KW   Glycosyltransferase {ECO:0000256|PIRNR:PIRNR006250,
KW   ECO:0000313|EMBL:CAI85484.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006843};
KW   Transferase {ECO:0000256|PIRNR:PIRNR006250,
KW   ECO:0000313|EMBL:CAI85484.1}.
FT   DOMAIN       27    113       QRPTase_N. {ECO:0000259|Pfam:PF02749}.
FT   DOMAIN      116    279       QRPTase_C. {ECO:0000259|Pfam:PF01729}.
FT   REGION      136    138       Substrate binding. {ECO:0000256|PIRSR:
FT                                PIRSR006250-1}.
FT   REGION      243    245       Substrate binding. {ECO:0000256|PIRSR:
FT                                PIRSR006250-1}.
FT   REGION      264    266       Substrate binding. {ECO:0000256|PIRSR:
FT                                PIRSR006250-1}.
FT   BINDING     103    103       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR006250-1}.
FT   BINDING     160    160       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR006250-1}.
FT   BINDING     170    170       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR006250-1}.
FT   BINDING     199    199       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR006250-1}.
FT   BINDING     220    220       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR006250-1}.
SQ   SEQUENCE   281 AA;  30254 MW;  FC019DDD2099D517 CRC64;
     MPIPHTLVSQ LVTLALGEDL NYQSAENGDI TAQLIPVNEQ ANAKVITRED CIFCGKDLII
     EVFKQVDPSV VVNVLVNDGD AVKANSTLFT ATGSARAILT AERTALNFVQ TLSGTATTTA
     HYVKELAGTK TQLLDTRKTI PGLRILQKYA VKCGGGANHR IGLYDAFLIK ENHIAACGGI
     NKAVAQAKQN QPNKPIEVEV ESLVDLKQAL DAGADIIMLD NFNVEQIKQA VVVTNKRAKL
     EVSGNMTLQT LKTYSQAGVD FISSGALTKN LQSIDLSMRF D
//

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