(data stored in ACNUC7421 zone)

SWISSPROT: Q3IIH0_PSEHT

ID   Q3IIH0_PSEHT            Unreviewed;       281 AA.
AC   Q3IIH0;
DT   08-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   08-NOV-2005, sequence version 1.
DT   07-JUN-2017, entry version 82.
DE   SubName: Full=3-hydroxybutyryl-CoA dehydrogenase (Beta-hydroxybutyryl-CoA dehydrogenase) (BHBD) {ECO:0000313|EMBL:CAI85497.1};
DE            EC=1.1.1.157 {ECO:0000313|EMBL:CAI85497.1};
GN   Name=bhbD {ECO:0000313|EMBL:CAI85497.1};
GN   OrderedLocusNames=PSHAa0399 {ECO:0000313|EMBL:CAI85497.1};
OS   Pseudoalteromonas haloplanktis (strain TAC 125).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Pseudoalteromonadaceae; Pseudoalteromonas.
OX   NCBI_TaxID=326442 {ECO:0000313|EMBL:CAI85497.1, ECO:0000313|Proteomes:UP000006843};
RN   [1] {ECO:0000313|EMBL:CAI85497.1, ECO:0000313|Proteomes:UP000006843}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TAC 125 {ECO:0000313|Proteomes:UP000006843};
RX   PubMed=16169927; DOI=10.1101/gr.4126905;
RA   Medigue C., Krin E., Pascal G., Barbe V., Bernsel A., Bertin P.,
RA   Cheung F., Cruveiller S., Damico S., Duilio A., Fang G., Feller G.,
RA   Mangenot S., Marino G., Nilsson J., Parilli E., Rocha E., Rouy Z.,
RA   Sekowska A., Tutino M.L., Vallenet D., von Heijne G., Danchin A.;
RT   "Coping with cold: the genome of the versatile marine Antarctica
RT   bacterium Pseudoalteromonas haloplanktis TAC125.";
RL   Genome Res. 15:1325-1335(2005).
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DR   EMBL; CR954246; CAI85497.1; -; Genomic_DNA.
DR   RefSeq; WP_011327110.1; NC_007481.1.
DR   ProteinModelPortal; Q3IIH0; -.
DR   STRING; 326442.PSHAa0399; -.
DR   EnsemblBacteria; CAI85497; CAI85497; PSHAa0399.
DR   KEGG; pha:PSHAa0399; -.
DR   PATRIC; fig|326442.8.peg.384; -.
DR   eggNOG; ENOG4105DYT; Bacteria.
DR   eggNOG; COG1250; LUCA.
DR   HOGENOM; HOG000141498; -.
DR   KO; K00074; -.
DR   OMA; MAHPMGP; -.
DR   OrthoDB; POG091H0NDD; -.
DR   Proteomes; UP000006843; Chromosome I.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0008691; F:3-hydroxybutyryl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.1040.10; -; 1.
DR   InterPro; IPR022694; 3-OHacyl-CoA_DH.
DR   InterPro; IPR006180; 3-OHacyl-CoA_DH_CS.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH_C-like.
DR   InterPro; IPR013328; 6PGD_dom_2.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   PIRSF; PIRSF000105; HCDH; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00067; 3HCDH; 1.
PE   4: Predicted;
DR   PRODOM; Q3IIH0.
DR   SWISS-2DPAGE; Q3IIH0.
KW   Complete proteome {ECO:0000313|Proteomes:UP000006843};
KW   Oxidoreductase {ECO:0000256|SAAS:SAAS00649305,
KW   ECO:0000313|EMBL:CAI85497.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006843}.
FT   DOMAIN        3    182       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      185    281       3HCDH. {ECO:0000259|Pfam:PF00725}.
FT   SITE        139    139       Important for catalytic activity.
FT                                {ECO:0000256|PIRSR:PIRSR000105-1}.
SQ   SEQUENCE   281 AA;  30333 MW;  1B09AD35492E88A4 CRC64;
     MEVSIIGSGT MATGITQVLC LSNEVSKVNL IARTEEKALA SKSTCAKNIS RLARKGKISD
     EQASFALEKL YCNAELVAVV NSDLIIEAIV EDFTAKMVLF SKLAEFINDS VIVASNTSSL
     SITAFASVLP NPQNVVGLHF FNPAPIMELV EIIVGHETAP AKIQLLQGLT KNLGKVPVVV
     QEAPGFVVNR MLIPMINEAV SILAEGVATA DDIDKAMKFG AHHPMGPLAL ADLIGNDVNL
     SIMETLYSET GDPKYRAHPL LRKMVRANHL GRKTKKGFFE Y
//

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