(data stored in ACNUC7421 zone)

SWISSPROT: TRMN6_PSEHT

ID   TRMN6_PSEHT             Reviewed;         232 AA.
AC   Q3IG80;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   07-JUN-2017, entry version 70.
DE   RecName: Full=tRNA1(Val) (adenine(37)-N6)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_01872};
DE            EC=2.1.1.223 {ECO:0000255|HAMAP-Rule:MF_01872};
DE   AltName: Full=tRNA m6A37 methyltransferase {ECO:0000255|HAMAP-Rule:MF_01872};
GN   OrderedLocusNames=PSHAa0511;
OS   Pseudoalteromonas haloplanktis (strain TAC 125).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Pseudoalteromonadaceae; Pseudoalteromonas.
OX   NCBI_TaxID=326442;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TAC 125;
RX   PubMed=16169927; DOI=10.1101/gr.4126905;
RA   Medigue C., Krin E., Pascal G., Barbe V., Bernsel A., Bertin P.N.,
RA   Cheung F., Cruveiller S., D'Amico S., Duilio A., Fang G., Feller G.,
RA   Ho C., Mangenot S., Marino G., Nilsson J., Parrilli E., Rocha E.P.C.,
RA   Rouy Z., Sekowska A., Tutino M.L., Vallenet D., von Heijne G.,
RA   Danchin A.;
RT   "Coping with cold: the genome of the versatile marine Antarctica
RT   bacterium Pseudoalteromonas haloplanktis TAC125.";
RL   Genome Res. 15:1325-1335(2005).
CC   -!- FUNCTION: Specifically methylates the adenine in position 37 of
CC       tRNA(1)(Val) (anticodon cmo5UAC). {ECO:0000255|HAMAP-
CC       Rule:MF_01872}.
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + adenine(37) in
CC       tRNA(1)(Val) = S-adenosyl-L-homocysteine + N(6)-methyladenine(37)
CC       in tRNA(1)(Val). {ECO:0000255|HAMAP-Rule:MF_01872}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01872}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. tRNA
CC       (adenine-N(6)-)-methyltransferase family. {ECO:0000255|HAMAP-
CC       Rule:MF_01872}.
DR   EMBL; CR954246; CAI85601.1; -; Genomic_DNA.
DR   RefSeq; WP_011327214.1; NC_007481.1.
DR   ProteinModelPortal; Q3IG80; -.
DR   SMR; Q3IG80; -.
DR   STRING; 326442.PSHAa0511; -.
DR   EnsemblBacteria; CAI85601; CAI85601; PSHAa0511.
DR   KEGG; pha:PSHAa0511; -.
DR   PATRIC; fig|326442.8.peg.480; -.
DR   eggNOG; ENOG4107S47; Bacteria.
DR   eggNOG; COG4123; LUCA.
DR   HOGENOM; HOG000283147; -.
DR   KO; K15460; -.
DR   OMA; DKCAMKV; -.
DR   OrthoDB; POG091H04RM; -.
DR   BioCyc; PHAL326442:GJIU-515-MONOMER; -.
DR   Proteomes; UP000006843; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0016430; F:tRNA (adenine-N6-)-methyltransferase activity; IEA:InterPro.
DR   HAMAP; MF_01872; tRNA_methyltr_YfiC; 1.
DR   InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR   InterPro; IPR029063; SAM-dependent_MTases.
DR   InterPro; IPR007848; Small_mtfrase_dom.
DR   InterPro; IPR022882; tRNA_adenine-N6_MeTrfase.
DR   Pfam; PF05175; MTS; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   PROSITE; PS00092; N6_MTASE; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q3IG80.
DR   SWISS-2DPAGE; Q3IG80.
KW   Complete proteome; Cytoplasm; Methyltransferase; Reference proteome;
KW   S-adenosyl-L-methionine; Transferase; tRNA processing.
FT   CHAIN         1    232       tRNA1(Val) (adenine(37)-N6)-
FT                                methyltransferase.
FT                                /FTId=PRO_0000387402.
SQ   SEQUENCE   232 AA;  25482 MW;  F1B621CB9B4CB2DA CRC64;
     MSGFAFKQFK VAHEQCAMKV STDGILLGAW ANLSNANSLL DIGTGTGLLA LMCKQRSPQL
     TITAVEVDKN AYQQALQNIA ASPWPNIEVH QQSIQTFNSA QPFDVVIANP PYFNHSLKGN
     NKARNIARHT DGLSFAELIS AFKKLSHAGS TFSLILPTTE VAVFIELATQ NGLFLNTHCQ
     VKATPNKAIS RSLMTFSYIN QSIVESALCI KDNENNYSED YIALCKAFYL KM
//

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