(data stored in ACNUC29543 zone)

SWISSPROT: A5GPX2_SYNR3

ID   A5GPX2_SYNR3            Unreviewed;       341 AA.
AC   A5GPX2;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   08-MAY-2019, entry version 84.
DE   RecName: Full=Glyceraldehyde-3-phosphate dehydrogenase {ECO:0000256|RuleBase:RU361160};
DE            EC=1.2.1.- {ECO:0000256|RuleBase:RU361160};
GN   Name=gap1 {ECO:0000313|EMBL:CAK26931.1};
GN   OrderedLocusNames=SynRCC307_0028 {ECO:0000313|EMBL:CAK26931.1};
OS   Synechococcus sp. (strain RCC307).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae;
OC   Synechococcus.
OX   NCBI_TaxID=316278 {ECO:0000313|EMBL:CAK26931.1, ECO:0000313|Proteomes:UP000001115};
RN   [1] {ECO:0000313|EMBL:CAK26931.1, ECO:0000313|Proteomes:UP000001115}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RCC307 {ECO:0000313|Proteomes:UP000001115};
RA   Genoscope;
RL   Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glyceraldehyde-3-phosphate
CC       dehydrogenase family. {ECO:0000256|RuleBase:RU000397}.
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DR   EMBL; CT978603; CAK26931.1; -; Genomic_DNA.
DR   RefSeq; WP_011934446.1; NC_009482.1.
DR   STRING; 316278.SynRCC307_0028; -.
DR   EnsemblBacteria; CAK26931; CAK26931; SynRCC307_0028.
DR   KEGG; syr:SynRCC307_0028; -.
DR   eggNOG; ENOG4105C17; Bacteria.
DR   eggNOG; COG0057; LUCA.
DR   HOGENOM; HOG000071679; -.
DR   KO; K00150; -.
DR   OMA; NAKVLAW; -.
DR   OrthoDB; 944149at2; -.
DR   BioCyc; SSP316278:G1GJL-28-MONOMER; -.
DR   Proteomes; UP000001115; Chromosome.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:InterPro.
DR   InterPro; IPR020831; GlycerAld/Erythrose_P_DH.
DR   InterPro; IPR020830; GlycerAld_3-P_DH_AS.
DR   InterPro; IPR020829; GlycerAld_3-P_DH_cat.
DR   InterPro; IPR020828; GlycerAld_3-P_DH_NAD(P)-bd.
DR   InterPro; IPR006424; Glyceraldehyde-3-P_DH_1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF02800; Gp_dh_C; 1.
DR   Pfam; PF00044; Gp_dh_N; 1.
DR   PIRSF; PIRSF000149; GAP_DH; 1.
DR   PRINTS; PR00078; G3PDHDRGNASE.
DR   SMART; SM00846; Gp_dh_N; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR01534; GAPDH-I; 1.
DR   PROSITE; PS00071; GAPDH; 1.
PE   3: Inferred from homology;
DR   PRODOM; A5GPX2.
DR   SWISS-2DPAGE; A5GPX2.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001115};
KW   NAD {ECO:0000256|PIRSR:PIRSR000149-3};
KW   Nucleotide-binding {ECO:0000256|PIRSR:PIRSR000149-3};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU361160,
KW   ECO:0000313|EMBL:CAK26931.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001115}.
FT   DOMAIN        3    157       Gp_dh_N. {ECO:0000259|SMART:SM00846}.
FT   NP_BIND      12     13       NAD. {ECO:0000256|PIRSR:PIRSR000149-3}.
FT   REGION      156    158       Glyceraldehyde 3-phosphate binding.
FT                                {ECO:0000256|PIRSR:PIRSR000149-2}.
FT   REGION      215    216       Glyceraldehyde 3-phosphate binding.
FT                                {ECO:0000256|PIRSR:PIRSR000149-2}.
FT   ACT_SITE    157    157       Nucleophile. {ECO:0000256|PIRSR:
FT                                PIRSR000149-1}.
FT   BINDING      37     37       NAD. {ECO:0000256|PIRSR:PIRSR000149-3}.
FT   BINDING      82     82       NAD; via carbonyl oxygen.
FT                                {ECO:0000256|PIRSR:PIRSR000149-3}.
FT   BINDING     124    124       NAD. {ECO:0000256|PIRSR:PIRSR000149-3}.
FT   BINDING     187    187       Glyceraldehyde 3-phosphate.
FT                                {ECO:0000256|PIRSR:PIRSR000149-2}.
FT   BINDING     238    238       Glyceraldehyde 3-phosphate.
FT                                {ECO:0000256|PIRSR:PIRSR000149-2}.
FT   BINDING     320    320       NAD. {ECO:0000256|PIRSR:PIRSR000149-3}.
FT   SITE        184    184       Activates thiol group during catalysis.
FT                                {ECO:0000256|PIRSR:PIRSR000149-4}.
SQ   SEQUENCE   341 AA;  37047 MW;  4B1731E27A5AFFED CRC64;
     MTLRVAINGF GRIGRNFMRC WLSRGANTGI EVVGLNDTSD PATNSHLLTY DTMLGRIRDA
     EISHTENTII ANGHEIKCFS DRNPLNLPWK EWGIDLVIES TGVFNTDEKA SMHIQAGAKK
     VILTAPGKGD GVGTFVVGVN ADQYRHEDFD ILSNASCTTN CMAPIVKVID QEFGIVKGSM
     TTVHSYTGDQ RILDASHRDL RRARAAAMNI VPTTTGAAKA VALVYPEVKG KLDGLALRVP
     TPNVSLVDMV FNVSKDTSRE EVNAVLKAAS EGAYKGIIKY STLPLVSSDL AGTDDSTIVD
     AELTKVMGGD QVKILSWYDN EWGYSQRVVD LAEIVAQRWA A
//

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