(data stored in ACNUC29543 zone)

SWISSPROT: A5GQ75_SYNR3

ID   A5GQ75_SYNR3            Unreviewed;       415 AA.
AC   A5GQ75;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   08-MAY-2019, entry version 78.
DE   RecName: Full=3-oxoacyl-[acyl-carrier-protein] synthase 2 {ECO:0000256|PIRNR:PIRNR000447};
DE            EC=2.3.1.179 {ECO:0000256|PIRNR:PIRNR000447};
GN   Name=fabF {ECO:0000313|EMBL:CAK27034.1};
GN   OrderedLocusNames=SynRCC307_0131 {ECO:0000313|EMBL:CAK27034.1};
OS   Synechococcus sp. (strain RCC307).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae;
OC   Synechococcus.
OX   NCBI_TaxID=316278 {ECO:0000313|EMBL:CAK27034.1, ECO:0000313|Proteomes:UP000001115};
RN   [1] {ECO:0000313|Proteomes:UP000001115}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RCC307 {ECO:0000313|Proteomes:UP000001115};
RG   Genoscope;
RL   Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the condensation reaction of fatty acid
CC       synthesis by the addition to an acyl acceptor of two carbons from
CC       malonyl-ACP. {ECO:0000256|PIRNR:PIRNR000447}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(11Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-
CC         (13Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP];
CC         Xref=Rhea:RHEA:14565, Rhea:RHEA-COMP:9623, Rhea:RHEA-COMP:9685,
CC         Rhea:RHEA-COMP:9921, Rhea:RHEA-COMP:9922, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:64479, ChEBI:CHEBI:78449,
CC         ChEBI:CHEBI:78778, ChEBI:CHEBI:78779; EC=2.3.1.179;
CC         Evidence={ECO:0000256|PIRNR:PIRNR000447};
CC   -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC       {ECO:0000256|PIRNR:PIRNR000447}.
CC   -!- SIMILARITY: Belongs to the beta-ketoacyl-ACP synthases family.
CC       {ECO:0000256|PIRNR:PIRNR000447, ECO:0000256|RuleBase:RU003694,
CC       ECO:0000256|SAAS:SAAS01172730}.
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DR   EMBL; CT978603; CAK27034.1; -; Genomic_DNA.
DR   RefSeq; WP_011934549.1; NC_009482.1.
DR   STRING; 316278.SynRCC307_0131; -.
DR   EnsemblBacteria; CAK27034; CAK27034; SynRCC307_0131.
DR   KEGG; syr:SynRCC307_0131; -.
DR   eggNOG; ENOG4105C0Q; Bacteria.
DR   eggNOG; COG0304; LUCA.
DR   HOGENOM; HOG000060166; -.
DR   KO; K09458; -.
DR   OMA; QIGHCLG; -.
DR   OrthoDB; 606297at2; -.
DR   BioCyc; SSP316278:G1GJL-131-MONOMER; -.
DR   UniPathway; UPA00094; -.
DR   Proteomes; UP000001115; Chromosome.
DR   GO; GO:0033817; F:beta-ketoacyl-acyl-carrier-protein synthase II activity; IEA:UniProtKB-EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR017568; 3-oxoacyl-ACP_synth-2.
DR   InterPro; IPR000794; Beta-ketoacyl_synthase.
DR   InterPro; IPR018201; Ketoacyl_synth_AS.
DR   InterPro; IPR014031; Ketoacyl_synth_C.
DR   InterPro; IPR014030; Ketoacyl_synth_N.
DR   InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11712; PTHR11712; 1.
DR   Pfam; PF00109; ketoacyl-synt; 1.
DR   Pfam; PF02801; Ketoacyl-synt_C; 1.
DR   PIRSF; PIRSF000447; KAS_II; 1.
DR   SMART; SM00825; PKS_KS; 1.
DR   SUPFAM; SSF53901; SSF53901; 2.
DR   TIGRFAMs; TIGR03150; fabF; 1.
DR   PROSITE; PS00606; B_KETOACYL_SYNTHASE; 1.
PE   3: Inferred from homology;
DR   PRODOM; A5GQ75.
DR   SWISS-2DPAGE; A5GQ75.
KW   Acyltransferase {ECO:0000256|PIRNR:PIRNR000447,
KW   ECO:0000313|EMBL:CAK27034.1};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001115};
KW   Fatty acid biosynthesis {ECO:0000256|PIRNR:PIRNR000447};
KW   Fatty acid metabolism {ECO:0000256|PIRNR:PIRNR000447};
KW   Lipid biosynthesis {ECO:0000256|PIRNR:PIRNR000447};
KW   Lipid metabolism {ECO:0000256|PIRNR:PIRNR000447};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001115};
KW   Transferase {ECO:0000256|PIRNR:PIRNR000447,
KW   ECO:0000256|RuleBase:RU003694, ECO:0000256|SAAS:SAAS01184688,
KW   ECO:0000313|EMBL:CAK27034.1}.
FT   DOMAIN        8    410       PKS_KS. {ECO:0000259|SMART:SM00825}.
FT   ACT_SITE    166    166       {ECO:0000256|PIRSR:PIRSR000447-1}.
SQ   SEQUENCE   415 AA;  42273 MW;  AC663A2E825B908C CRC64;
     MAESSRRVVI TGLGAVTPIG NTVATYWAGL QSGANGVAPI TLFDASKHAC RFAAEVKDFD
     PTGVLDPKET KRWDRFCQFG VVAAKEALAH SGLEITDANR QRIGVIIGSG VGGLLTMETQ
     AHVLEGKGPG RVSPFTVPMM IPNMATGLAA IALGAQGPSS AVATACAAGS NAIGDAFRLL
     QQGHADAMIC GGAESAITPL GVAGFASAKA LSFRNDDPAT ASRPFDAERD GFVIGEGAGI
     LVLETLDHAQ ARGAEILGEV VGYGMTCDAH HITSPIPGGL GGARAMSLAL SDAGLKADDI
     DYVNAHGTST PANDSNETAA IKTALGERAK AIPVSSTKSM TGHLLGGSGG IEAVAAVLAL
     QNGVVPPTIN HQNPDPACDL DVVPNQAREQ IISTALSNSF GFGGHNVCLA FRRYA
//

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