(data stored in ACNUC7421 zone)

SWISSPROT: A2Q8G2_ASPNC

ID   A2Q8G2_ASPNC            Unreviewed;       481 AA.
AC   A2Q8G2;
DT   06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2007, sequence version 1.
DT   11-DEC-2019, entry version 79.
DE   RecName: Full=tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82 {ECO:0000256|HAMAP-Rule:MF_03056};
DE   AltName: Full=Transfer RNA methyltransferase 82 {ECO:0000256|HAMAP-Rule:MF_03056};
GN   Name=TRM82 {ECO:0000256|HAMAP-Rule:MF_03056};
GN   ORFNames=An01g04230 {ECO:0000313|EMBL:CAK36959.1};
OS   Aspergillus niger (strain CBS 513.88 / FGSC A1513).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=425011 {ECO:0000313|Proteomes:UP000006706};
RN   [1] {ECO:0000313|EMBL:CAK36959.1, ECO:0000313|Proteomes:UP000006706}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 513.88 / FGSC A1513 {ECO:0000313|Proteomes:UP000006706};
RX   PubMed=17259976; DOI=10.1038/nbt1282;
RA   Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA   Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA   Bendtsen J.D., Benen J.A., van den Berg M., Breestraat S., Caddick M.X.,
RA   Contreras R., Cornell M., Coutinho P.M., Danchin E.G., Debets A.J.,
RA   Dekker P., van Dijck P.W., van Dijk A., Dijkhuizen L., Driessen A.J.,
RA   d'Enfert C., Geysens S., Goosen C., Groot G.S., de Groot P.W.,
RA   Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.,
RA   van den Hondel C.A., van der Heijden R.T., van der Kaaij R.M., Klis F.M.,
RA   Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA   van der Maarel M.J., Meulenberg R., Menke H., Mortimer M.A., Nielsen J.,
RA   Oliver S.G., Olsthoorn M., Pal K., van Peij N.N., Ram A.F., Rinas U.,
RA   Roubos J.A., Sagt C.M., Schmoll M., Sun J., Ussery D., Varga J.,
RA   Vervecken W., van de Vondervoort P.J., Wedler H., Wosten H.A., Zeng A.P.,
RA   van Ooyen A.J., Visser J., Stam H.;
RT   "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT   niger CBS 513.88.";
RL   Nat. Biotechnol. 25:221-231(2007).
CC   -!- FUNCTION: Required for the formation of N(7)-methylguanine at position
CC       46 (m7G46) in tRNA. In the complex, it is required to stabilize and
CC       induce conformational changes of the catalytic subunit.
CC       {ECO:0000256|HAMAP-Rule:MF_03056}.
CC   -!- PATHWAY: tRNA modification; N(7)-methylguanine-tRNA biosynthesis.
CC       {ECO:0000256|HAMAP-Rule:MF_03056}.
CC   -!- SUBUNIT: Forms a heterodimer with the catalytic subunit TRM8.
CC       {ECO:0000256|HAMAP-Rule:MF_03056}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|HAMAP-Rule:MF_03056}.
CC   -!- SIMILARITY: Belongs to the WD repeat TRM82 family. {ECO:0000256|HAMAP-
CC       Rule:MF_03056}.
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DR   EMBL; AM269962; CAK36959.1; -; Genomic_DNA.
DR   RefSeq; XP_001388851.1; XM_001388814.2.
DR   PaxDb; A2Q8G2; -.
DR   EnsemblFungi; CAK36959; CAK36959; An01g04230.
DR   GeneID; 4978154; -.
DR   KEGG; ang:ANI_1_538014; -.
DR   HOGENOM; HOG000217089; -.
DR   KO; K15443; -.
DR   UniPathway; UPA00989; -.
DR   Proteomes; UP000006706; Chromosome 2R.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0036265; P:RNA (guanine-N7)-methylation; IEA:InterPro.
DR   GO; GO:0030488; P:tRNA methylation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_03056; TRM82; 1.
DR   InterPro; IPR028884; Trm82.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR16288; PTHR16288; 1.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
DR   PRODOM; A2Q8G2.
DR   SWISS-2DPAGE; A2Q8G2.
KW   Nucleus {ECO:0000256|HAMAP-Rule:MF_03056};
KW   Repeat {ECO:0000256|HAMAP-Rule:MF_03056};
KW   tRNA processing {ECO:0000256|HAMAP-Rule:MF_03056};
KW   WD repeat {ECO:0000256|HAMAP-Rule:MF_03056}.
FT   REGION          47..87
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          439..481
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        64..78
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        453..481
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   481 AA;  52721 MW;  6D44718728B0D4F7 CRC64;
     MSAHFQHPLQ CLRLVQRSTA NLLIGSAGSK LYSYSAETGQ RLAVWPEDVA SSETKPVDAE
     SAPEQGPPEK KRKVSSSDSP TIEKPAWSNI PIVTGTASGE HIIALTAEDK CVRVFQLQED
     GSFVQLSQRV MPKRPSAITL TDDDDTILCG DKFGDVYSLP LIPSDKLPAI TKSLRSAKLS
     HPAATNLTVH TKGNRRALEQ QLRLASEGKR DEKSSGPTFE HKILLGHVSL LTDMAYVSLP
     VDENKKRSYI LTADRDEHIR VSRGPPQAHV IENYCLGHTA FISKLCVPQW APQYLVSGGG
     DNYLLVWKWA EGRILQKVSL VDEASESTEV AVQGIWATSL GNLRIILVAL HGSSRLQCFT
     LESDGSLKTQ ASIQLSGNVL DLTPVEKDNT ILVSVDSIRQ PDSTQEWRTS PSSPSTLIEA
     FHIKSGTDSL EWEPTAASVT DKINSTGTEE VPATTEEKQR KELNDSLYGL GHLRKRKGED
     E
//

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