(data stored in ACNUC7421 zone)

SWISSPROT: A2Q8J8_ASPNC

ID   A2Q8J8_ASPNC            Unreviewed;       464 AA.
AC   A2Q8J8;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   11-DEC-2019, entry version 72.
DE   SubName: Full=PDI related protein A prpA-Aspergillus niger {ECO:0000313|EMBL:CAK36995.1};
DE            EC=5.3.4.1 {ECO:0000313|EMBL:CAK36995.1};
GN   Name=prpA {ECO:0000313|EMBL:CAK36995.1};
GN   ORFNames=An01g04600 {ECO:0000313|EMBL:CAK36995.1};
OS   Aspergillus niger (strain CBS 513.88 / FGSC A1513).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=425011 {ECO:0000313|Proteomes:UP000006706};
RN   [1] {ECO:0000313|EMBL:CAK36995.1, ECO:0000313|Proteomes:UP000006706}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 513.88 / FGSC A1513 {ECO:0000313|Proteomes:UP000006706};
RX   PubMed=17259976; DOI=10.1038/nbt1282;
RA   Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA   Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA   Bendtsen J.D., Benen J.A., van den Berg M., Breestraat S., Caddick M.X.,
RA   Contreras R., Cornell M., Coutinho P.M., Danchin E.G., Debets A.J.,
RA   Dekker P., van Dijck P.W., van Dijk A., Dijkhuizen L., Driessen A.J.,
RA   d'Enfert C., Geysens S., Goosen C., Groot G.S., de Groot P.W.,
RA   Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.,
RA   van den Hondel C.A., van der Heijden R.T., van der Kaaij R.M., Klis F.M.,
RA   Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA   van der Maarel M.J., Meulenberg R., Menke H., Mortimer M.A., Nielsen J.,
RA   Oliver S.G., Olsthoorn M., Pal K., van Peij N.N., Ram A.F., Rinas U.,
RA   Roubos J.A., Sagt C.M., Schmoll M., Sun J., Ussery D., Varga J.,
RA   Vervecken W., van de Vondervoort P.J., Wedler H., Wosten H.A., Zeng A.P.,
RA   van Ooyen A.J., Visser J., Stam H.;
RT   "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT   niger CBS 513.88.";
RL   Nat. Biotechnol. 25:221-231(2007).
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DR   EMBL; AM269963; CAK36995.1; -; Genomic_DNA.
DR   RefSeq; XP_001388887.1; XM_001388850.1.
DR   PaxDb; A2Q8J8; -.
DR   EnsemblFungi; CAK36995; CAK36995; An01g04600.
DR   GeneID; 4978424; -.
DR   KEGG; ang:ANI_1_2488014; -.
DR   HOGENOM; HOG000210812; -.
DR   KO; K09584; -.
DR   Proteomes; UP000006706; Chromosome 2R.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   Gene3D; 3.40.30.10; -; 2.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR017937; Thioredoxin_CS.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   Pfam; PF00085; Thioredoxin; 1.
DR   SUPFAM; SSF52833; SSF52833; 2.
DR   PROSITE; PS00194; THIOREDOXIN_1; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   4: Predicted;
DR   PRODOM; A2Q8J8.
DR   SWISS-2DPAGE; A2Q8J8.
KW   Isomerase {ECO:0000313|EMBL:CAK36995.1}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..464
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002644044"
FT   DOMAIN          14..144
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
FT   REGION          244..292
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        259..276
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   464 AA;  50261 MW;  67A3F9058908C8F1 CRC64;
     MLQPSSALLF VTSLLAALPV NADGLYTKKS PVLQVNQKNY DQLIANSNHT SIVEFYAPWC
     GHCQNLKPAY EKAATNLDGL AKVAAVNCDY DDNKPFCGRM GVQGFPTLKI VTPGKKPGKP
     RVEDYKGARS AKAIVEAVVD RIPNHVKRAT DKDLDTWLAQ DEESPKAILF TEKGTTSPLL
     RALAIDFLGS IQVAQVRNKE TEAVEKFGIT EFPTFVLLPG GGQDPIVYDG ELKKKPMVEF
     LSQAAAPNPD PAPKGSTAPR DNNKKKSTEP SPDSKIVSDE AKPASVPIPA PPIGTLPTAE
     ALEAACLMPK SGTCVLALLP EPSEPDAELP APAKDALLSL AEISHKHAVR KSKLFPFYSV
     PAINSGAKTL RAGLGLPEDN SVEIVAVNGR RGWWRRYDSV EGAEYGQERV EAWIDAIRLG
     EGEKQKLPDG VVVEEVVEEK VEEKVEEVVE EPVEEKPAVD HDEL
//

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