(data stored in ACNUC7421 zone)

SWISSPROT: A2Q823_ASPNC

ID   A2Q823_ASPNC            Unreviewed;       613 AA.
AC   A2Q823;
DT   06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2007, sequence version 1.
DT   11-DEC-2019, entry version 56.
DE   RecName: Full=Signal recognition particle subunit SRP68 {ECO:0000256|PIRNR:PIRNR038995};
DE            Short=SRP68 {ECO:0000256|PIRNR:PIRNR038995};
GN   ORFNames=An01g02800 {ECO:0000313|EMBL:CAK43646.1};
OS   Aspergillus niger (strain CBS 513.88 / FGSC A1513).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=425011 {ECO:0000313|Proteomes:UP000006706};
RN   [1] {ECO:0000313|EMBL:CAK43646.1, ECO:0000313|Proteomes:UP000006706}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 513.88 / FGSC A1513 {ECO:0000313|Proteomes:UP000006706};
RX   PubMed=17259976; DOI=10.1038/nbt1282;
RA   Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA   Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA   Bendtsen J.D., Benen J.A., van den Berg M., Breestraat S., Caddick M.X.,
RA   Contreras R., Cornell M., Coutinho P.M., Danchin E.G., Debets A.J.,
RA   Dekker P., van Dijck P.W., van Dijk A., Dijkhuizen L., Driessen A.J.,
RA   d'Enfert C., Geysens S., Goosen C., Groot G.S., de Groot P.W.,
RA   Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.,
RA   van den Hondel C.A., van der Heijden R.T., van der Kaaij R.M., Klis F.M.,
RA   Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA   van der Maarel M.J., Meulenberg R., Menke H., Mortimer M.A., Nielsen J.,
RA   Oliver S.G., Olsthoorn M., Pal K., van Peij N.N., Ram A.F., Rinas U.,
RA   Roubos J.A., Sagt C.M., Schmoll M., Sun J., Ussery D., Varga J.,
RA   Vervecken W., van de Vondervoort P.J., Wedler H., Wosten H.A., Zeng A.P.,
RA   van Ooyen A.J., Visser J., Stam H.;
RT   "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT   niger CBS 513.88.";
RL   Nat. Biotechnol. 25:221-231(2007).
CC   -!- FUNCTION: Signal-recognition-particle assembly has a crucial role in
CC       targeting secretory proteins to the rough endoplasmic reticulum
CC       membrane. {ECO:0000256|PIRNR:PIRNR038995}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR038995}.
CC   -!- SIMILARITY: Belongs to the SRP68 family.
CC       {ECO:0000256|PIRNR:PIRNR038995}.
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DR   EMBL; AM269955; CAK43646.1; -; Genomic_DNA.
DR   RefSeq; XP_001388714.1; XM_001388677.1.
DR   PaxDb; A2Q823; -.
DR   EnsemblFungi; CAK43646; CAK43646; An01g02800.
DR   GeneID; 4978210; -.
DR   KEGG; ang:ANI_1_348014; -.
DR   HOGENOM; HOG000211745; -.
DR   KO; K03107; -.
DR   Proteomes; UP000006706; Chromosome 2R.
DR   GO; GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IEA:UniProtKB-KW.
DR   GO; GO:0008312; F:7S RNA binding; IEA:InterPro.
DR   GO; GO:0030942; F:endoplasmic reticulum signal peptide binding; IEA:InterPro.
DR   GO; GO:0005047; F:signal recognition particle binding; IEA:InterPro.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro.
DR   CDD; cd15481; SRP68-RBD; 1.
DR   Gene3D; 1.10.3450.40; -; 1.
DR   InterPro; IPR026258; SRP68.
DR   InterPro; IPR034652; SRP68-RBD.
DR   InterPro; IPR038253; SRP68_N_sf.
DR   PANTHER; PTHR12860; PTHR12860; 1.
DR   Pfam; PF16969; SRP68; 1.
DR   PIRSF; PIRSF038995; SRP68; 1.
PE   3: Inferred from homology;
DR   PRODOM; A2Q823.
DR   SWISS-2DPAGE; A2Q823.
KW   Cytoplasm {ECO:0000256|PIRNR:PIRNR038995};
KW   Ribonucleoprotein {ECO:0000256|PIRNR:PIRNR038995};
KW   RNA-binding {ECO:0000256|PIRNR:PIRNR038995};
KW   Signal recognition particle {ECO:0000256|PIRNR:PIRNR038995}.
FT   REGION          583..613
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   613 AA;  67377 MW;  12CD254CE33B822B CRC64;
     MEITDFIFSQ REESLLTGNY NAYRAHTTRK LHSARLRLGQ TTPKRSKYIA KRPVTAEDVN
     SNVEYVHTLL ISAERAWANA MHMKTTHSAD PSAKGVSGTT RGHIISKLRK AVTFAKQLVH
     VLEDQETSGA ADTDVLEARA YLASLLGAYF LEKRNWEQCL QNYSVSRVIY AALGQQVKKD
     AFRDLLSGTV DPSIRYAAYQ LKLPRSKPIP SLALSYFPSD ATIRSEVEKL DPNCLKEDAA
     GTRRTADGEV QQLPGSVTWR SHTVGLEDAA ISQALASAAA AESRLTTWLA EGEGKNASSK
     DKAAAYDNVI IASQDAVDAT KTAIDDLAGE GVDPSDKRMQ ALQITRTAVN YDLVGWRIGR
     NRVLCGDNDG VSFESVSTKL PKSAKATAKQ DDATGKKLAR LRERVVLYDS TLQSIEFILE
     LPGVAADTAF VRELDAKRRY FRALRCLTIG RSHGILGKST NALALFAQAL ALVTETARSP
     QSLTETEGPP RLDISRSQVQ TLELTLKGLV AQYRGLVTLE KMSAEAQSKS VTQRPAVERL
     HDFAGDALDL TNIVPYPPQM QPIPVKPLFL DVAWNYIEYP RQSTPAADNS QAQPEPQPEE
     KKGGRRGWFG FGR
//

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