(data stored in ACNUC1104 zone)

SWISSPROT: A4F5S4_SACEN

ID   A4F5S4_SACEN            Unreviewed;       436 AA.
AC   A4F5S4;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   08-MAY-2019, entry version 66.
DE   SubName: Full=Putative serine/threonine protein kinase {ECO:0000313|EMBL:CAL99398.1};
DE            EC=2.7.11.1 {ECO:0000313|EMBL:CAL99398.1};
DE   SubName: Full=Serine/threonine-protein kinase {ECO:0000313|EMBL:PFG93198.1};
GN   Name=pknA {ECO:0000313|EMBL:CAL99398.1};
GN   OrderedLocusNames=SACE_0045 {ECO:0000313|EMBL:CAL99398.1};
GN   ORFNames=A8924_0429 {ECO:0000313|EMBL:PFG93198.1};
OS   Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748
OS   / NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
OC   Saccharopolyspora.
OX   NCBI_TaxID=405948 {ECO:0000313|EMBL:CAL99398.1, ECO:0000313|Proteomes:UP000006728};
RN   [1] {ECO:0000313|EMBL:CAL99398.1, ECO:0000313|Proteomes:UP000006728}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC   NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC   {ECO:0000313|EMBL:CAL99398.1};
RX   PubMed=17369815; DOI=10.1038/nbt1297;
RA   Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N.,
RA   Dickens S., Haydock S.F., Leadlay P.F.;
RT   "Complete genome sequence of the erythromycin-producing bacterium
RT   Saccharopolyspora erythraea NRRL23338.";
RL   Nat. Biotechnol. 25:447-453(2007).
RN   [2] {ECO:0000313|EMBL:PFG93198.1, ECO:0000313|Proteomes:UP000225825}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG93198.1,
RC   ECO:0000313|Proteomes:UP000225825};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AM420293; CAL99398.1; -; Genomic_DNA.
DR   EMBL; PDBV01000001; PFG93198.1; -; Genomic_DNA.
DR   RefSeq; WP_009950431.1; NZ_PDBV01000001.1.
DR   STRING; 405948.SACE_0045; -.
DR   EnsemblBacteria; CAL99398; CAL99398; SACE_0045.
DR   KEGG; sen:SACE_0045; -.
DR   eggNOG; ENOG4107TPY; Bacteria.
DR   eggNOG; COG0515; LUCA.
DR   HOGENOM; HOG000037187; -.
DR   KO; K12132; -.
DR   OMA; KHPWVVS; -.
DR   OrthoDB; 1377603at2; -.
DR   BioCyc; SERY405948:SACE_RS00210-MONOMER; -.
DR   Proteomes; UP000006728; Chromosome.
DR   Proteomes; UP000225825; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; SSF56112; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
DR   PRODOM; A4F5S4.
DR   SWISS-2DPAGE; A4F5S4.
KW   Complete proteome {ECO:0000313|Proteomes:UP000006728,
KW   ECO:0000313|Proteomes:UP000225825};
KW   Kinase {ECO:0000313|EMBL:CAL99398.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006728};
KW   Serine/threonine-protein kinase {ECO:0000313|EMBL:CAL99398.1};
KW   Transferase {ECO:0000313|EMBL:CAL99398.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    346    368       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       12    273       Protein kinase. {ECO:0000259|PROSITE:
FT                                PS50011}.
SQ   SEQUENCE   436 AA;  46123 MW;  86AB41854B55BD41 CRC64;
     MLTTGQLLAE RYRLGQRIAV GGMGEVWKAT DVRLDRTVAI KVLKAELCGN AEFLHRFRTE
     ARTTASLNHP GIAAVHDYGE TAAIPDGPED TAYLVMELVE GEPLAATLAR EGRIKAEHAL
     DMLEQAGHAL QAAHERGLVH RDVKPGNILI TPNGKVKLTD FGIAKAADAA PVTRSGMVMG
     TAHYIAPEQA LGSEATPASD VYSLAVVGYE CLKGHRPFLS DNAVTVAMMH IREVAPPLPP
     DVPPGARALI EATLVKDPRR RYATGGEFAN AVAAVRAGLP LPTPAALAVP QQRQQMGTPV
     PGTGVHQLPP AMPPMQNTYP PGLIPPQAAA PQPPPPAPRP RYSRTMIWVA VSVVVVVALT
     AIGIAVALRT TNGQGVPHND PERTRQVAAG AATNHLDSAD RFDQTALRPV RGTNRTNTHQ
     STEVGGTAHG VQRGTS
//

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