(data stored in SCRATCH zone)

SWISSPROT: A4F5V8_SACEN

ID   A4F5V8_SACEN            Unreviewed;       255 AA.
AC   A4F5V8;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   11-DEC-2019, entry version 75.
DE   SubName: Full=Osmoprotectant transport system permease protein {ECO:0000313|EMBL:PFG93231.1};
DE   SubName: Full=Probable ABC quaternary amine transporter,permease component {ECO:0000313|EMBL:CAL99432.1};
GN   OrderedLocusNames=SACE_0079 {ECO:0000313|EMBL:CAL99432.1};
GN   ORFNames=A8924_0464 {ECO:0000313|EMBL:PFG93231.1};
OS   Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS   NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
OC   Saccharopolyspora.
OX   NCBI_TaxID=405948 {ECO:0000313|EMBL:CAL99432.1, ECO:0000313|Proteomes:UP000006728};
RN   [1] {ECO:0000313|EMBL:CAL99432.1, ECO:0000313|Proteomes:UP000006728}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC   NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC   {ECO:0000313|EMBL:CAL99432.1};
RX   PubMed=17369815; DOI=10.1038/nbt1297;
RA   Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA   Haydock S.F., Leadlay P.F.;
RT   "Complete genome sequence of the erythromycin-producing bacterium
RT   Saccharopolyspora erythraea NRRL23338.";
RL   Nat. Biotechnol. 25:447-453(2007).
RN   [2] {ECO:0000313|EMBL:PFG93231.1, ECO:0000313|Proteomes:UP000225825}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG93231.1,
RC   ECO:0000313|Proteomes:UP000225825};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363032};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363032}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. {ECO:0000256|RuleBase:RU363032}.
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DR   EMBL; AM420293; CAL99432.1; -; Genomic_DNA.
DR   EMBL; PDBV01000001; PFG93231.1; -; Genomic_DNA.
DR   RefSeq; WP_009949864.1; NZ_PDBV01000001.1.
DR   STRING; 405948.SACE_0079; -.
DR   EnsemblBacteria; CAL99432; CAL99432; SACE_0079.
DR   KEGG; sen:SACE_0079; -.
DR   eggNOG; ENOG4108UCZ; Bacteria.
DR   eggNOG; COG1174; LUCA.
DR   HOGENOM; HOG000012907; -.
DR   KO; K05846; -.
DR   OMA; WQHVLIT; -.
DR   OrthoDB; 1233189at2; -.
DR   BioCyc; SERY405948:SACE_RS00370-MONOMER; -.
DR   Proteomes; UP000006728; Chromosome.
DR   Proteomes; UP000225825; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
DR   PRODOM; A4F5V8.
DR   SWISS-2DPAGE; A4F5V8.
KW   Cell membrane {ECO:0000256|SAAS:SAAS01214637};
KW   Membrane {ECO:0000256|RuleBase:RU363032, ECO:0000256|SAAS:SAAS00819239};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006728};
KW   Transmembrane {ECO:0000256|RuleBase:RU363032,
KW   ECO:0000256|SAAS:SAAS00984863};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU363032,
KW   ECO:0000256|SAAS:SAAS00985050}; Transport {ECO:0000256|RuleBase:RU363032}.
FT   TRANSMEM        20..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363032"
FT   TRANSMEM        59..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363032"
FT   TRANSMEM        95..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363032"
FT   TRANSMEM        124..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363032"
FT   TRANSMEM        189..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363032"
FT   TRANSMEM        221..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363032"
FT   DOMAIN          59..242
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000259|PROSITE:PS50928"
SQ   SEQUENCE   255 AA;  26924 MW;  F19DD34740DB679D CRC64;
     MSSQYASDSG SRRAERLRLL LQPVAVLAIV GSVLGWAFSQ DLDEVTARSI NATNIVSLTW
     QHFLLSLAVA VIVVVVAVPM GVLLSRPWAR RVSPVVIGIA NVGQAAPSVG LLVLFFLATK
     GSTGFWIAVL PIAVYALLPV LRNTMVGLQQ VDRSLVDAGR GIGMSAVKVL LRIELPLSVP
     YILAGLRTAL VLAVGTATLA LFVGAGGLGE LIDTGYKLNN WTVMCVGSVL AMALALLVDW
     LAALAEEYLS PRGLR
//

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