(data stored in ACNUC1104 zone)

SWISSPROT: A4F5Z8_SACEN

ID   A4F5Z8_SACEN            Unreviewed;       585 AA.
AC   A4F5Z8;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   08-MAY-2019, entry version 70.
DE   SubName: Full=Sodium:solute symporter family protein {ECO:0000313|EMBL:PFG93271.1};
DE   SubName: Full=Sodium:solute symporter, SSF {ECO:0000313|EMBL:CAL99472.1};
GN   OrderedLocusNames=SACE_0119 {ECO:0000313|EMBL:CAL99472.1};
GN   ORFNames=A8924_0505 {ECO:0000313|EMBL:PFG93271.1};
OS   Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748
OS   / NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
OC   Saccharopolyspora.
OX   NCBI_TaxID=405948 {ECO:0000313|EMBL:CAL99472.1, ECO:0000313|Proteomes:UP000006728};
RN   [1] {ECO:0000313|EMBL:CAL99472.1, ECO:0000313|Proteomes:UP000006728}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC   NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC   {ECO:0000313|EMBL:CAL99472.1};
RX   PubMed=17369815; DOI=10.1038/nbt1297;
RA   Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N.,
RA   Dickens S., Haydock S.F., Leadlay P.F.;
RT   "Complete genome sequence of the erythromycin-producing bacterium
RT   Saccharopolyspora erythraea NRRL23338.";
RL   Nat. Biotechnol. 25:447-453(2007).
RN   [2] {ECO:0000313|EMBL:PFG93271.1, ECO:0000313|Proteomes:UP000225825}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG93271.1,
RC   ECO:0000313|Proteomes:UP000225825};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the sodium:solute symporter (SSF)
CC       (TC 2.A.21) family. {ECO:0000256|RuleBase:RU362091}.
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DR   EMBL; AM420293; CAL99472.1; -; Genomic_DNA.
DR   EMBL; PDBV01000001; PFG93271.1; -; Genomic_DNA.
DR   RefSeq; WP_009949295.1; NZ_PDBV01000001.1.
DR   STRING; 405948.SACE_0119; -.
DR   EnsemblBacteria; CAL99472; CAL99472; SACE_0119.
DR   KEGG; sen:SACE_0119; -.
DR   eggNOG; ENOG4107RZJ; Bacteria.
DR   eggNOG; COG4147; LUCA.
DR   HOGENOM; HOG000242184; -.
DR   OMA; WYPIGFT; -.
DR   OrthoDB; 278483at2; -.
DR   BioCyc; SERY405948:SACE_RS00570-MONOMER; -.
DR   Proteomes; UP000006728; Chromosome.
DR   Proteomes; UP000225825; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1730.10; -; 2.
DR   InterPro; IPR038377; Na/Glc_symporter_sf.
DR   InterPro; IPR001734; Na/solute_symporter.
DR   Pfam; PF00474; SSF; 2.
DR   PROSITE; PS50283; NA_SOLUT_SYMP_3; 1.
PE   3: Inferred from homology;
DR   PRODOM; A4F5Z8.
DR   SWISS-2DPAGE; A4F5Z8.
KW   Complete proteome {ECO:0000313|Proteomes:UP000006728,
KW   ECO:0000313|Proteomes:UP000225825};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006728};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM      6     26       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     47     69       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     75     95       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    116    133       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    153    172       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    184    203       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    304    325       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    337    357       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    386    418       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    430    446       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    458    478       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    485    506       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    518    536       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   585 AA;  62326 MW;  E31738E4998AC098 CRC64;
     MSSSIWALSG IGVIAAATFG IGFWGARNAR ATSDFLAARQ SVREERNAAA ISGEYLSAAS
     FLGIAGLVLK EGVDALWYPI GFAAGYLALM LFVAAPLRRS GAYTLPDFAE ERLDSLPLRW
     LSTALVVLIG WLYLVPQMQA AGLTLSSVTG HPYWVGVLAV TGLVLVSALS GGMRAVTLVQ
     AFQYWVKLFA ITLPAFVLFF VFMTGDAQHQ RALDSPAPPV FERDTAVHFE TDVRLRVDEP
     VWVQVVGAEH GTVYMRPGEH PVSTGVVLRF PAGSPVPVVD DAEPDNASWL RPQDGGIRGL
     VETYSVIMAT FLGTMGLPHV LARFYSNPNG QGARRTTLYV LALLGAFYLF PTVFGLLSRF
     YVPMLLVTGE TDAAVLLLPH LMLGNWLGGL LGAVTAAGAF AAFLSTSSGL LVSVAGVLSA
     DVLRGRAVDV RLVMVVSCVL PTLLALRMSD QDITQSVGLA FAMAASTFCP MLVLGIWWRG
     LTAAGAAAGL VTGGGLVLVA VVVSMLTGDD GSWVSALSWQ PAVVTVPVAF LVTWGVSRAT
     RRRVPAGVSR VMLRMHAPDR LGFIDDRTSV RGVPQEPKTG RHLRE
//

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