(data stored in ACNUC1104 zone)

SWISSPROT: A4F609_SACEN

ID   A4F609_SACEN            Unreviewed;       186 AA.
AC   A4F609;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   08-MAY-2019, entry version 74.
DE   RecName: Full=Ferritin {ECO:0000256|RuleBase:RU361145};
DE            EC=1.16.3.2 {ECO:0000256|RuleBase:RU361145};
GN   OrderedLocusNames=SACE_0130 {ECO:0000313|EMBL:CAL99483.1};
GN   ORFNames=A8924_0516 {ECO:0000313|EMBL:PFG93282.1};
OS   Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748
OS   / NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
OC   Saccharopolyspora.
OX   NCBI_TaxID=405948 {ECO:0000313|EMBL:CAL99483.1, ECO:0000313|Proteomes:UP000006728};
RN   [1] {ECO:0000313|EMBL:CAL99483.1, ECO:0000313|Proteomes:UP000006728}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC   NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC   {ECO:0000313|EMBL:CAL99483.1};
RX   PubMed=17369815; DOI=10.1038/nbt1297;
RA   Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N.,
RA   Dickens S., Haydock S.F., Leadlay P.F.;
RT   "Complete genome sequence of the erythromycin-producing bacterium
RT   Saccharopolyspora erythraea NRRL23338.";
RL   Nat. Biotechnol. 25:447-453(2007).
RN   [2] {ECO:0000313|EMBL:PFG93282.1, ECO:0000313|Proteomes:UP000225825}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG93282.1,
RC   ECO:0000313|Proteomes:UP000225825};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Iron-storage protein. {ECO:0000256|RuleBase:RU361145}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=4 Fe(2+) + 6 H2O + O2 = 12 H(+) + 4 iron(III) oxide-
CC         hydroxide; Xref=Rhea:RHEA:11972, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:29033,
CC         ChEBI:CHEBI:78619; EC=1.16.3.2;
CC         Evidence={ECO:0000256|RuleBase:RU361145};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU361145}.
CC   -!- SIMILARITY: Belongs to the ferritin family. Prokaryotic subfamily.
CC       {ECO:0000256|RuleBase:RU361145}.
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DR   EMBL; AM420293; CAL99483.1; -; Genomic_DNA.
DR   EMBL; PDBV01000001; PFG93282.1; -; Genomic_DNA.
DR   RefSeq; WP_009949282.1; NZ_PDBV01000001.1.
DR   STRING; 405948.SACE_0130; -.
DR   EnsemblBacteria; CAL99483; CAL99483; SACE_0130.
DR   KEGG; sen:SACE_0130; -.
DR   eggNOG; ENOG4107YEV; Bacteria.
DR   eggNOG; COG1528; LUCA.
DR   HOGENOM; HOG000223382; -.
DR   KO; K22336; -.
DR   OMA; CEDKGFE; -.
DR   OrthoDB; 1890523at2; -.
DR   BioCyc; SERY405948:SACE_RS00620-MONOMER; -.
DR   Proteomes; UP000006728; Chromosome.
DR   Proteomes; UP000225825; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008199; F:ferric iron binding; IEA:InterPro.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IEA:UniProtKB-KW.
DR   GO; GO:0006826; P:iron ion transport; IEA:InterPro.
DR   CDD; cd01055; Nonheme_Ferritin; 1.
DR   Gene3D; 1.20.1260.10; -; 1.
DR   InterPro; IPR001519; Ferritin.
DR   InterPro; IPR012347; Ferritin-like.
DR   InterPro; IPR009040; Ferritin-like_diiron.
DR   InterPro; IPR009078; Ferritin-like_SF.
DR   InterPro; IPR008331; Ferritin_DPS_dom.
DR   InterPro; IPR041719; Ferritin_prok.
DR   PANTHER; PTHR11431; PTHR11431; 1.
DR   Pfam; PF00210; Ferritin; 1.
DR   SUPFAM; SSF47240; SSF47240; 1.
DR   PROSITE; PS50905; FERRITIN_LIKE; 1.
PE   3: Inferred from homology;
DR   PRODOM; A4F609.
DR   SWISS-2DPAGE; A4F609.
KW   Complete proteome {ECO:0000313|Proteomes:UP000006728,
KW   ECO:0000313|Proteomes:UP000225825};
KW   Cytoplasm {ECO:0000256|RuleBase:RU361145};
KW   Iron {ECO:0000256|RuleBase:RU361145};
KW   Iron storage {ECO:0000256|RuleBase:RU361145};
KW   Metal-binding {ECO:0000256|RuleBase:RU361145};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006728}.
FT   DOMAIN        9    154       Ferritin-like diiron.
FT                                {ECO:0000259|PROSITE:PS50905}.
SQ   SEQUENCE   186 AA;  21189 MW;  F82493DFBDE7519B CRC64;
     MAITAKKIER RESKFHQLLQ EQVHNEFTAS QQYIAVAVWF DNEDLPRLAS HFYKQALEER
     NHAMMIVQYL MDNNIKPNIP GVPDVRNDFS ETRELVALAL EQEREVTQEI VNLAKTAREE
     GDYLGEQFMQ WFLKEQVEEV SQMSTLLNVV DRSNGNLFDV ETFLARETVG DEGADSGAPP
     AAGGTL
//

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